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Flavonoids and the CNS

Molecules, 2011-02, Vol.16 (2), p.1471-1485

2011

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Considerations regarding use of solvents in in vitro cell based assays

Cytotechnology (Dordrecht), 2013-10, Vol.65 (5), p.887-894

2013

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Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

Fluids and barriers of the CNS, 2024-01, Vol.21 (1), p.11-11, Article 11

2024

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Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

Scientific reports, 2024-04, Vol.14 (1), p.7665-7665

2024

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Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

Stem cell research, 2024-04, Vol.76, p.103348-103348, Article 103348

2024

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A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

PloS one, 2021-10, Vol.16 (10), p.e0258207-e0258207

2021

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Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates

European journal of pharmaceutical sciences, 2018-01, Vol.112, p.112-121

2018

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Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

Food science & technology, 2016-12, Vol.74, p.404-410

2016

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A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2257-2264

2017

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MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull

Journal of ethnopharmacology, 2009-01, Vol.121 (1), p.178-181

2009

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IPEC-J2 rMdr1a, a New Cell Line with Functional Expression of Rat P-glycoprotein Encoded by Rat Mdr1a for Drug Screening Purposes

Pharmaceutics, 2020-07, Vol.12 (7), p.673

2020

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Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

Current pharmaceutical design, 2015-01, Vol.21 (19), p.2611

2015

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Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration

Frontiers in microbiology, 2022-01, Vol.12, p.786173-786173

2022

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Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates

Data in brief, 2018-02, Vol.16, p.655-659

2018

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The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

Cells (Basel, Switzerland), 2020-03, Vol.9 (3), p.613

2020

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A Novel Derivative of Thioridazine Shows Low Toxicity and Efficient Activity against Gram-Positive Pathogens

Antibiotics (Basel), 2020-06, Vol.9 (6), p.327

2020

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Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease

Gastroenterology (New York, N.Y. 1943), 2021-07, Vol.161 (1), p.81-93.e3

2021

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Hydrolysed pea proteins mitigate in vitro wheat starch digestibility

Food hydrocolloids, 2018-06, Vol.79, p.117-126

2018

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SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

International journal of pharmaceutics, 2019-04, Vol.560, p.377-384

2019

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Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

European journal of pharmaceutics and biopharmaceutics, 2022-05, Vol.174, p.106-110

2022

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IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P‑glycoprotein (ABCB1) for Drug Screening Studies

Molecular pharmaceutics, 2016-02, Vol.13 (2), p.640-652

2016

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Abstract 6340: Re-sensitization of irinotecan/SN38 resistant colorectal cancer cells by SCO-101

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6340-6340

2020

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Drug Delivery Strategies to Overcome the Blood–Brain Barrier (BBB)

Physiology, Pharmacology and Pathology of the Blood-Brain Barrier, p.151-183

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Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

European journal of pharmaceutics and biopharmaceutics, 2021-12, Vol.169, p.211-219

2021

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Dark chocolate as a stable carrier of microencapsulated Akkermansia muciniphila and Lactobacillus casei

FEMS microbiology letters, 2019-01, Vol.366 (2), p.1

2019

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Flavonoids and the CNS

Considerations regarding use of solvents in in vitro cell based assays

Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates

Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics

MAO-A inhibitory activity of quercetin from Calluna vulgaris (L.) Hull

IPEC-J2 rMdr1a, a New Cell Line with Functional Expression of Rat P-glycoprotein Encoded by Rat Mdr1a for Drug Screening Purposes

Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration

Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates

The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

A Novel Derivative of Thioridazine Shows Low Toxicity and Efficient Activity against Gram-Positive Pathogens

Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease

Hydrolysed pea proteins mitigate in vitro wheat starch digestibility

SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P‑glycoprotein (ABCB1) for Drug Screening Studies

Abstract 6340: Re-sensitization of irinotecan/SN38 resistant colorectal cancer cells by SCO-101

Drug Delivery Strategies to Overcome the Blood–Brain Barrier (BBB)

Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

Dark chocolate as a stable carrier of microencapsulated Akkermansia muciniphila and Lactobacillus casei

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