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Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.1517-1522

2015

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Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination

The Journal of immunology (1950), 2016-11, Vol.197 (10), p.4014-4020

2016

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Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research

BMC bioinformatics, 2008-12, Vol.9 Suppl 12 (S12), p.S22-S22, Article S22

2008

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Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.E2182-E2190

2014

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Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility

Nature communications, 2023-11, Vol.14 (1), p.7218-7218, Article 7218

2023

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Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

Nature communications, 2022-10, Vol.13 (1), p.6393-6393, Article 6393

2022

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HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane

Immunity (Cambridge, Mass.), 2008-01, Vol.28 (1), p.52-63

2008

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αβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapy

Cancer immunology research, 2015-04, Vol.3 (4), p.305-312

Reinherz, Ellis L

2015

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Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research

BMC immunology, 2008-03, Vol.9 (1), p.8-8, Article 8

2008

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Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.379-384

2014

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Topological analysis of the gp41 MPER on lipid bilayers relevant to the metastable HIV-1 envelope prefusion state

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (45), p.22556-22566

2019

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Asymmetric framework motion of TCRαβ controls load-dependent peptide discrimination

eLife, 2024-01, Vol.13

2024

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Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (7), p.2151-2156

2015

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Pre-TCR ligand binding impacts thymocyte development before αβTCR expression

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8373-8378

2015

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Sequence Variability Analysis of Human Class I and Class II MHC Molecules: Functional and Structural Correlates of Amino Acid Polymorphisms

Journal of molecular biology, 2003-08, Vol.331 (3), p.623-641

2003

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The structure of a T-cell mechanosensor

Nature (London), 2019-09, Vol.573 (7775), p.502-504

Reinherz, Ellis L

2019

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Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display

Frontiers in immunology, 2019-12, Vol.10, p.2766-2766

2019

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Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry

The Journal of biological chemistry, 2013-11, Vol.288 (44), p.31888-31901

2013

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Prediction of peptide-MHC binding using profiles

Methods in molecular biology (Clifton, N.J.), 2007, Vol.409, p.185

2007

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αβ T Cell Receptor Mechanosensing Forces out Serial Engagement

Trends in immunology, 2018-08, Vol.39 (8), p.596-609

2018

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Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (22), p.9057-9062

2009

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Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41

Journal of molecular biology, 2014-03, Vol.426 (5), p.1095-1108

2014

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Mechanosensing drives acuity of αβ T-cell recognition

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (39), p.E8204-E8213

2017

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Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity

Journal of virology, 2016-10, Vol.90 (19), p.8875-8890

2016

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Revisiting the Discovery of the αβ TCR Complex and Its Co-Receptors

Frontiers in immunology, 2014, Vol.5, p.583-583

Reinherz, Ellis L

2014

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Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime

Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination

Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research

Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells

Inadequate structural constraint on Fab approach rather than paratope elicitation limits HIV-1 MPER vaccine utility

Dynamic HIV-1 spike motion creates vulnerability for its membrane-bound tripod to antibody attack

HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane

αβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapy

Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research

Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis

Topological analysis of the gp41 MPER on lipid bilayers relevant to the metastable HIV-1 envelope prefusion state

Asymmetric framework motion of TCRαβ controls load-dependent peptide discrimination

Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity

Pre-TCR ligand binding impacts thymocyte development before αβTCR expression

Sequence Variability Analysis of Human Class I and Class II MHC Molecules: Functional and Structural Correlates of Amino Acid Polymorphisms

The structure of a T-cell mechanosensor

Cancer Neoepitopes for Immunotherapy: Discordance Between Tumor-Infiltrating T Cell Reactivity and Tumor MHC Peptidome Display

Immunogenicity of Membrane-bound HIV-1 gp41 Membrane-proximal External Region (MPER) Segments Is Dominated by Residue Accessibility and Modulated by Stereochemistry

Prediction of peptide-MHC binding using profiles

αβ T Cell Receptor Mechanosensing Forces out Serial Engagement

Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface

Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41

Mechanosensing drives acuity of αβ T-cell recognition

Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity

Revisiting the Discovery of the αβ TCR Complex and Its Co-Receptors

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