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Enlargement of a Modular System-Synthesis and Characterization of an s -Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3288

2019

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

Cancer research (Chicago, Ill.), 2004-10, Vol.64 (19), p.7099-7109

2004

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Combined Tyrosine and Serine/Threonine Kinase Inhibition by Sorafenib Prevents Progression of Experimental Pulmonary Hypertension and Myocardial Remodeling

Circulation (New York, N.Y.), 2008-11, Vol.118 (20), p.2081-2090

2008

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Design and discovery of small molecules targeting raf-1 kinase

Current pharmaceutical design, 2002-01, Vol.8 (25), p.2269

2002

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A Scaleable Synthesis of BAY 43-9006: A Potent Raf Kinase Inhibitor for the Treatment of Cancer

Organic process research & development, 2002-11, Vol.6 (6), p.777-781

2002

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Selective Neuropeptide Y Conjugates with Maximized Carborane Loading as Promising Boron Delivery Agents for Boron Neutron Capture Therapy

Journal of medicinal chemistry, 2020-03, Vol.63 (5), p.2358-2371

2020

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Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13693-13703

2021

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MO053INHIBITION OF SODIUM PHOSPHATE TRANSPORTER NPT2A IMPROVES EXPERIMENTAL VASCULAR CALCIFICATION AND PHOSPHATE HOMEOSTASIS IN RATS

Nephrology, dialysis, transplantation, 2020-06, Vol.35 (Supplement_3)

2020

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A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture Therapy

Journal of organic chemistry, 2020-02, Vol.85 (3), p.1446-1457

2020

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Von Steinkohlenteer bis zu Krebsmedikamenten

Chemie in unserer Zeit, 2014-04, Vol.48 (2), p.124-132

2014

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Modular triazine-based carborane-containing carboxylic acids - synthesis and characterisation of potential boron neutron capture therapy agents made of readily accessible building blocks

Dalton transactions : an international journal of inorganic chemistry, 2019-08, Vol.48 (29), p.1834-1844

2019

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Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist

Science China. Chemistry, 2019-10, Vol.62 (10), p.1371-1378

2019

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Tuning a modular system - synthesis and characterisation of a boron-rich s-triazine-based carboxylic acid and amine bearing a galactopyranosyl moiety

Dalton transactions : an international journal of inorganic chemistry, 2020-01, Vol.49 (1), p.57-69

2020

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Von Steinkohlenteer bis zu Krebsmedikamenten: 150 Jahre Bayer

Chemie in unserer Zeit, 2014-04, Vol.48 (2), p.124-132

2014

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Pinpointing the interaction site between semaphorin‐3A and its inhibitory peptide

Journal of peptide science, 2023-04, Vol.29 (4), p.e3460-n/a

2023

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Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interactionElectronic supplementary information (ESI) available: Experimental details and compound characterization. See DOI: 10.1039/c9cc00328b

2019-02

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Synthesis of bromodifluoromethyl(arylsulfonyl) compounds and microwave-assisted nickel catalyzed cross coupling with arylboronic acids

Tetrahedron letters, 2016-12, Vol.57 (49), p.5464-5468

2016

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Rational design of highly stabilized and selective adrenomedullin analogs

Journal of peptide science, 2023-12, Vol.29 (12), p.e3530-e3530

2023

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A stable meta‐carborane enables the generation of boron‐rich peptide agonists targeting the ghrelin receptor

Journal of peptide science, 2018-10, Vol.24 (10), p.e3119-n/a

2018

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Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5695-5705

2016

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Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential

ChemMedChem, 2016-11, Vol.11 (21), p.2378-2384

2016

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Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interaction

Chemical communications (Cambridge, England), 2019-02, Vol.55 (19), p.2821-2824

2019

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Adrenomedullin disulfide bond mimetics uncover structural requirements for AM 1 receptor activation

Journal of peptide science, 2019-03, Vol.25 (3), p.e3147

2019

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Diastereoselective Formation of (Z)-Didehydroamino Acid Esters

Synthesis (Stuttgart), 1992, Vol.1992 (5), p.487-490

1992

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Adrenomedullin disulfide bond mimetics uncover structural requirements for AM1 receptor activation

Journal of peptide science, 2019-03, Vol.25 (3), p.e3147-n/a

2019

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Enlargement of a Modular System-Synthesis and Characterization of an s -Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

Combined Tyrosine and Serine/Threonine Kinase Inhibition by Sorafenib Prevents Progression of Experimental Pulmonary Hypertension and Myocardial Remodeling

Design and discovery of small molecules targeting raf-1 kinase

A Scaleable Synthesis of BAY 43-9006: A Potent Raf Kinase Inhibitor for the Treatment of Cancer

Selective Neuropeptide Y Conjugates with Maximized Carborane Loading as Promising Boron Delivery Agents for Boron Neutron Capture Therapy

Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2

MO053INHIBITION OF SODIUM PHOSPHATE TRANSPORTER NPT2A IMPROVES EXPERIMENTAL VASCULAR CALCIFICATION AND PHOSPHATE HOMEOSTASIS IN RATS

A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture Therapy

Von Steinkohlenteer bis zu Krebsmedikamenten

Modular triazine-based carborane-containing carboxylic acids - synthesis and characterisation of potential boron neutron capture therapy agents made of readily accessible building blocks

Chimeric protein probes for C5a receptors through fusion of the anaphylatoxin C5a core region with a small-molecule antagonist

Tuning a modular system - synthesis and characterisation of a boron-rich s-triazine-based carboxylic acid and amine bearing a galactopyranosyl moiety

Von Steinkohlenteer bis zu Krebsmedikamenten: 150 Jahre Bayer

Pinpointing the interaction site between semaphorin‐3A and its inhibitory peptide

Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interactionElectronic supplementary information (ESI) available: Experimental details and compound characterization. See DOI: 10.1039/c9cc00328b

Synthesis of bromodifluoromethyl(arylsulfonyl) compounds and microwave-assisted nickel catalyzed cross coupling with arylboronic acids

Rational design of highly stabilized and selective adrenomedullin analogs

A stable meta‐carborane enables the generation of boron‐rich peptide agonists targeting the ghrelin receptor

Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability

Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential

Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interaction

Adrenomedullin disulfide bond mimetics uncover structural requirements for AM 1 receptor activation

Diastereoselective Formation of (Z)-Didehydroamino Acid Esters

Adrenomedullin disulfide bond mimetics uncover structural requirements for AM1 receptor activation

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