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Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

Science translational medicine, 2014-12, Vol.6 (265), p.265ra169

2014

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Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies

The Journal of infectious diseases, 2010-11, Vol.202 (10), p.1492-1499

2010

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Synergistic Efficacy of the Combination of ST-246 with CMX001 against Orthopoxviruses

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.4118-4124

2007

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CMX001 Potentiates the Efficacy of Acyclovir in Herpes Simplex Virus Infections

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4728-4734

2011

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Efficacy of Delayed Treatment with ST-246 Given Orally against Systemic Orthopoxvirus Infections in Mice

Antimicrobial Agents and Chemotherapy, 2007-02, Vol.51 (2), p.689-695

2007

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Preclinical Evaluation of a Genetically Engineered Herpes Simplex Virus Expressing Interleukin-12

Journal of Virology, 2012-05, Vol.86 (9), p.5304-5313

2012

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Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir

Antimicrobial Agents and Chemotherapy, 2004-02, Vol.48 (2), p.404-412

2004

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Inhibition of Herpesvirus Replication by 5-Substituted 4′-Thiopyrimidine Nucleosides

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5251-5258

2009

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Oral Activity of a Methylenecyclopropane Analog, Cyclopropavir, in Animal Models for Cytomegalovirus Infections

Antimicrobial Agents and Chemotherapy, 2004-12, Vol.48 (12), p.4745-4753

2004

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Activity and Mechanism of Action of N-Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections

Antimicrobial Agents and Chemotherapy, 2006-04, Vol.50 (4), p.1336-1341

2006

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Treatment of Vaccinia and Cowpox Virus Infections in Mice with CMX001 and ST-246

Viruses, 2010-12, Vol.2 (12), p.2681-2695

2010

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Oral Treatment of Murine Cytomegalovirus Infections with Ether Lipid Esters of Cidofovir

Antimicrobial Agents and Chemotherapy, 2004-09, Vol.48 (9), p.3516-3522

2004

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Effect of Oral Treatment with Hexadecyloxypropyl-[(S)-9-(3-Hydroxy-2- Phosphonylmethoxypropyl)Adenine] [(S)-HPMPA] or Octadecyloxyethyl-(S)-HPMPA on Cowpox or Vaccinia Virus Infections in Mice

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3940-3947

2007

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Efficacy of Multiple- or Single-Dose Cidofovir against Vaccinia and Cowpox Virus Infections in Mice

Antimicrobial Agents and Chemotherapy, 2003-10, Vol.47 (10), p.3275-3280

2003

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Activities of Certain 5-Substituted 4′-Thiopyrimidine Nucleosides against Orthopoxvirus Infections

Antimicrobial Agents and Chemotherapy, 2009-02, Vol.53 (2), p.572-579

2009

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Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis

Antiviral research, 2018-01, Vol.149, p.1-6

2018

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Isolation and characterization of cidofovir resistant vaccinia viruses

Virology journal, 2008-05, Vol.5 (1), p.58-58, Article 58

2008

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In vitro and in vivo evaluation of isatin-β-thiosemicarbazone and marboran against vaccinia and cowpox virus infections

Antiviral research, 2006-08, Vol.71 (1), p.24-30

2006

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Use of Microsphere Technology for Targeted Delivery of Rifampin to Mycobacterium tuberculosis-Infected Macrophages

Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2682-2689

1998

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Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

Virology journal, 2008-03, Vol.5 (1), p.39-39

2008

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Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice

Virology journal, 2006-03, Vol.3 (1), p.18-18

2006

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Treatment of Tuberculosis Using a Combination of Sustained-Release Rifampin-Loaded Microspheres and Oral Dosing with Isoniazid

Antimicrobial Agents and Chemotherapy, 2001-06, Vol.45 (6), p.1637-1644

2001

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Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir

Bioorganic & medicinal chemistry, 2012-04, Vol.20 (8), p.2669-2674

2012

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Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs

Vaccine, 2005-11, Vol.23 (46), p.5424-5431

2005

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Efficacy of Orally Administered Low Dose N-methanocarbathymidine against Lethal Herpes Simplex Virus Type-2 Infections of Mice

Antiviral chemistry & chemotherapy, 2011-12, Vol.22 (3), p.131-137

2011

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Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies

Synergistic Efficacy of the Combination of ST-246 with CMX001 against Orthopoxviruses

CMX001 Potentiates the Efficacy of Acyclovir in Herpes Simplex Virus Infections

Efficacy of Delayed Treatment with ST-246 Given Orally against Systemic Orthopoxvirus Infections in Mice

Preclinical Evaluation of a Genetically Engineered Herpes Simplex Virus Expressing Interleukin-12

Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir

Inhibition of Herpesvirus Replication by 5-Substituted 4′-Thiopyrimidine Nucleosides

Oral Activity of a Methylenecyclopropane Analog, Cyclopropavir, in Animal Models for Cytomegalovirus Infections

Activity and Mechanism of Action of N-Methanocarbathymidine against Herpesvirus and Orthopoxvirus Infections

Treatment of Vaccinia and Cowpox Virus Infections in Mice with CMX001 and ST-246

Oral Treatment of Murine Cytomegalovirus Infections with Ether Lipid Esters of Cidofovir

Effect of Oral Treatment with Hexadecyloxypropyl-[(S)-9-(3-Hydroxy-2- Phosphonylmethoxypropyl)Adenine] [(S)-HPMPA] or Octadecyloxyethyl-(S)-HPMPA on Cowpox or Vaccinia Virus Infections in Mice

Efficacy of Multiple- or Single-Dose Cidofovir against Vaccinia and Cowpox Virus Infections in Mice

Activities of Certain 5-Substituted 4′-Thiopyrimidine Nucleosides against Orthopoxvirus Infections

Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis

Isolation and characterization of cidofovir resistant vaccinia viruses

In vitro and in vivo evaluation of isatin-β-thiosemicarbazone and marboran against vaccinia and cowpox virus infections

Use of Microsphere Technology for Targeted Delivery of Rifampin to Mycobacterium tuberculosis-Infected Macrophages

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice

Treatment of Tuberculosis Using a Combination of Sustained-Release Rifampin-Loaded Microspheres and Oral Dosing with Isoniazid

Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir

Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs

Efficacy of Orally Administered Low Dose N-methanocarbathymidine against Lethal Herpes Simplex Virus Type-2 Infections of Mice

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