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Basal insulin peglispro increases lipid oxidation, metabolic flexibility, thermogenesis and ketone bodies compared to insulin glargine in subjects with type 1 diabetes mellitus

Diabetes, obesity & metabolism, 2018-05, Vol.20 (5), p.1193-1201

2018

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Bedtime Administration of NN2211, a Long-Acting GLP-1 Derivative, Substantially Reduces Fasting and Postprandial Glycemia in Type 2 Diabetes

Diabetes (New York, N.Y.), 2002-02, Vol.51 (2), p.424-429

2002

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Mathematical models of diabetes progression

American journal of physiology: endocrinology and metabolism, 2008-12, Vol.295 (6), p.E1462-E1479

2008

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Pulsatile Insulin Secretion: Detection, Regulation, and Role in Diabetes

Diabetes (New York, N.Y.), 2002-02, Vol.51 (suppl 1), p.S245-S254

2002

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Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

The Journal of clinical investigation, 2004-06, Vol.113 (11), p.1571-1581

2004

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Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes

American journal of physiology: endocrinology and metabolism, 2000-09, Vol.279 (3), p.E520-E528

2000

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Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Gottingen minipigs in vivo

American journal of physiology: endocrinology and metabolism, 2006-04, Vol.290 (4), p.E670-E677

2006

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Acute Insulin Response and β-Cell Compensation in Normal Subjects Treated With Olanzapine or Risperidone for 2 Weeks

Diabetes care, 2007, Vol.30 (1), p.157-158

2007

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Individuelle Wege ins Arbeitsleben: Abschlussbericht zum Projekt "Bestandsaufnahme zur Rehabilitation psychisch Kranker"

Aktion Psychisch Kranke, Vereinigung zur Reform der Versorgung Psychisch Kranker

2004

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Glucagon-Like Peptide 1 Increases Secretory Burst Mass of Pulsatile Insulin Secretion in Patients With Type 2 Diabetes and Impaired Glucose Tolerance

Diabetes (New York, N.Y.), 2001-04, Vol.50 (4), p.776-784

2001

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In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts

American journal of physiology: endocrinology and metabolism, 1997-11, Vol.273 (5), p.E908-E914

1997

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Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein

Diabetes/metabolism research and reviews, 2010-05, Vol.26 (4), p.287-296

2010

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Evaluation of a mathematical model of diabetes progression against observations in the Diabetes Prevention Program

American journal of physiology: endocrinology and metabolism, 2012-07, Vol.303 (2), p.E200-E212

2012

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Therapy targeting β-cell survival and function in type 2 diabetes mellitus

Diabetes research and clinical practice, 2006-11, Vol.74 (2), p.S63-S69

Porksen, Niels

2006

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Acute and Short-Term Administration of a Sulfonylurea (Gliclazide) Increases Pulsatile Insulin Secretion in Type 2 Diabetes

Diabetes (New York, N.Y.), 2001-08, Vol.50 (8), p.1778-1784

2001

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Basal Insulin Peglispro Demonstrates Preferential Hepatic Versus Peripheral Action Relative to Insulin Glargine in Healthy Subjects

Diabetes care, 2014-09, Vol.37 (9), p.2609-2615

2014

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Human insulin release processes measured by intraportal sampling

American journal of physiology: endocrinology and metabolism, 2002-03, Vol.282 (3), p.E695-E702

2002

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Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass

Diabetes (New York, N.Y.), 1996-10, Vol.45 (10), p.1317

1996

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Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions

American journal of physiology: endocrinology and metabolism, 2000-01, Vol.278 (1), p.E162-E170

2000

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Attenuated suppression of lipolysis explains the increases in triglyceride secretion and concentration associated with basal insulin peglispro relative to insulin glargine treatment in patients with type 1 diabetes

Diabetes, obesity & metabolism, 2018-02, Vol.20 (2), p.419-426

2018

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Hypoglycemia Risk Related to Double Dose Is Markedly Reduced with Basal Insulin Peglispro Versus Insulin Glargine in Patients with Type 2 Diabetes Mellitus in a Randomized Trial: IMAGINE 8

Diabetes technology & therapeutics, 2017-08, Vol.19 (8), p.463

2017

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High-frequency oscillations in circulating amylin concentrations in healthy humans

American journal of physiology: endocrinology and metabolism, 2000-03, Vol.278 (3), p.E484-E490

2000

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Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion

Diabetes technology & therapeutics, 2017-05, Vol.19 (5), p.305

2017

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Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

The Journal of clinical investigation, 2004-06, Vol.113 (11), p.1571-1581

2004

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Basal insulin peglispro increases lipid oxidation, metabolic flexibility, thermogenesis and ketone bodies compared to insulin glargine in subjects with type 1 diabetes mellitus

Bedtime Administration of NN2211, a Long-Acting GLP-1 Derivative, Substantially Reduces Fasting and Postprandial Glycemia in Type 2 Diabetes

Mathematical models of diabetes progression

Pulsatile Insulin Secretion: Detection, Regulation, and Role in Diabetes

Hepatic and glucagon-like peptide-1–mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

Overnight inhibition of insulin secretion restores pulsatility and proinsulin/insulin ratio in type 2 diabetes

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Gottingen minipigs in vivo

Acute Insulin Response and β-Cell Compensation in Normal Subjects Treated With Olanzapine or Risperidone for 2 Weeks

Individuelle Wege ins Arbeitsleben: Abschlussbericht zum Projekt "Bestandsaufnahme zur Rehabilitation psychisch Kranker"

Glucagon-Like Peptide 1 Increases Secretory Burst Mass of Pulsatile Insulin Secretion in Patients With Type 2 Diabetes and Impaired Glucose Tolerance

In humans at least 75% of insulin secretion arises from punctuated insulin secretory bursts

Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein

Evaluation of a mathematical model of diabetes progression against observations in the Diabetes Prevention Program

Therapy targeting β-cell survival and function in type 2 diabetes mellitus

Acute and Short-Term Administration of a Sulfonylurea (Gliclazide) Increases Pulsatile Insulin Secretion in Type 2 Diabetes

Basal Insulin Peglispro Demonstrates Preferential Hepatic Versus Peripheral Action Relative to Insulin Glargine in Healthy Subjects

Human insulin release processes measured by intraportal sampling

Effects of glucose ingestion versus infusion on pulsatile insulin secretion. The incretin effect is achieved by amplification of insulin secretory burst mass

Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions

Attenuated suppression of lipolysis explains the increases in triglyceride secretion and concentration associated with basal insulin peglispro relative to insulin glargine treatment in patients with type 1 diabetes

Hypoglycemia Risk Related to Double Dose Is Markedly Reduced with Basal Insulin Peglispro Versus Insulin Glargine in Patients with Type 2 Diabetes Mellitus in a Randomized Trial: IMAGINE 8

High-frequency oscillations in circulating amylin concentrations in healthy humans

Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

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