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Metabolic Imaging of Glutamine in Cancer

Journal of Nuclear Medicine, 2017-04, Vol.58 (4), p.533-537

2017

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[ 18 F](2 S ,4 R )4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition

Cancer research (Chicago, Ill.), 2017-03, Vol.77 (6), p.1476-1484

2017

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Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

Science translational medicine, 2015-02, Vol.7 (274), p.274ra17

2015

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Enantioselective Radiosynthesis of Positron Emission Tomography (PET) Tracers Containing [18F]Fluorohydrins

Journal of the American Chemical Society, 2014-04, Vol.136 (14), p.5291-5294

2014

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Synthesis of Optically Pure 4-Fluoro-Glutamines as Potential Metabolic Imaging Agents for Tumors

Journal of the American Chemical Society, 2011-02, Vol.133 (4), p.1122-1133

2011

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Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors

Journal of Nuclear Medicine, 2012-01, Vol.53 (1), p.98-105

2012

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Biodistribution, dosimetry, and temporal signal-to-noise ratio analyses of normal and cancer uptake of [68Ga]Ga-P15-041, a gallium-68 labeled bisphosphonate, from first-in-human studies

Nuclear medicine and biology, 2020-07, Vol.86-87, p.1-8

2020

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Optimization and scale up of production of the PSMA imaging agent [18F]AlF-P16-093 on a custom automated radiosynthesis platform

EJNMMI radiopharmacy and chemistry, 2024-02, Vol.9 (1), p.15-15

2024

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PET/SPECT imaging agents for neurodegenerative diseases

Chemical Society reviews, 2014-10, Vol.43 (19), p.6683-6691

2014

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Comparative evaluation of 18F-labeled glutamic acid and glutamine as tumor metabolic imaging agents

The Journal of nuclear medicine (1978), 2012-10, Vol.53 (10), p.1616-1624

2012

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Facile Synthesis [5-13 C-4-2 H2 ]-L-Glutamine for Hyperpolarized MRS Imaging of Cancer Cell Metabolism

Academic radiology, 2011-08, Vol.18 (8), p.932-939

2011

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Synthesis and evaluation of 18F labeled FET prodrugs for tumor imaging

Nuclear medicine and biology, 2014-01, Vol.41 (1), p.58-67

2014

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Theranostic Agent Targeting Bone Metastasis: A Novel [68Ga]Ga/[177Lu]Lu-DOTA-HBED-bisphosphonate

Journal of medicinal chemistry, 2024-03, Vol.67 (6), p.4793-4803

2024

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Lu-177-Labeled Hetero-Bivalent Agents Targeting PSMA and Bone Metastases for Radionuclide Therapy

Journal of medicinal chemistry, 2023-09, Vol.66 (17), p.12602-12613

2023

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New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.13001-13012

2022

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Synthesis and Evaluation of 68Ga- and 177Lu-Labeled (R)- vs (S)‑DOTAGA Prostate-Specific Membrane Antigen-Targeting Derivatives

Molecular pharmaceutics, 2020-12, Vol.17 (12), p.4589-4602

2020

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Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093

Bioconjugate chemistry, 2021-05, Vol.32 (5), p.1017-1026

2021

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(68)Ga-Bivalent Polypegylated Styrylpyridine Conjugates for Imaging Aβ Plaques in Cerebral Amyloid Angiopathy

Bioconjugate chemistry, 2016-05, Vol.27 (5), p.1314-1323

2016

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Preclinical evaluation of [18F]D3FSP, deuterated AV-45, for imaging of β-amyloid in the brain

Nuclear medicine and biology, 2021-01, Vol.92, p.97-106

2021

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Synthesis and evaluation of a novel urea-based 68Ga-complex for imaging PSMA binding in tumor

Nuclear medicine and biology, 2018-04, Vol.59, p.36-47

2018

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A New [68Ga]Ga-HBED-CC-Bisphosphonate as a Bone Imaging Agent

Molecular pharmaceutics, 2020-05, Vol.17 (5), p.1674-1684

2020

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Expanding the Scope of Fluorine Tags for PET Imaging

Science (American Association for the Advancement of Science), 2013-10, Vol.342 (6157), p.429-430

2013

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[68Ga]Ga-HBED-CC-FAPI derivatives with improved radiolabeling and specific tumor uptake

Nuclear medicine and biology, 2023-11, Vol.126-127, p.108806, Article 108806

2023

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Optimization of solid phase extraction (SPE) in preparation of D3-[18F]FSP: A new PET imaging agent for mapping Aβ plaques

The Journal of nuclear medicine (1978), 2019-05, Vol.60

2019

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Kit-based preparation of [68Ga]Ga-P16-093 (PSMA-093) using different commercial 68Ge/68Ga generators

Nuclear medicine and biology, 2022-03, Vol.106-107, p.1-9

2022

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Metabolic Imaging of Glutamine in Cancer

[ 18 F](2 S ,4 R )4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition

Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo

Enantioselective Radiosynthesis of Positron Emission Tomography (PET) Tracers Containing [18F]Fluorohydrins

Synthesis of Optically Pure 4-Fluoro-Glutamines as Potential Metabolic Imaging Agents for Tumors

Preparation and characterization of L-[5-11C]-glutamine for metabolic imaging of tumors

Biodistribution, dosimetry, and temporal signal-to-noise ratio analyses of normal and cancer uptake of [68Ga]Ga-P15-041, a gallium-68 labeled bisphosphonate, from first-in-human studies

Optimization and scale up of production of the PSMA imaging agent [18F]AlF-P16-093 on a custom automated radiosynthesis platform

PET/SPECT imaging agents for neurodegenerative diseases

Comparative evaluation of 18F-labeled glutamic acid and glutamine as tumor metabolic imaging agents

Facile Synthesis [5-13 C-4-2 H2 ]-L-Glutamine for Hyperpolarized MRS Imaging of Cancer Cell Metabolism

Synthesis and evaluation of 18F labeled FET prodrugs for tumor imaging

Theranostic Agent Targeting Bone Metastasis: A Novel [68Ga]Ga/[177Lu]Lu-DOTA-HBED-bisphosphonate

Lu-177-Labeled Hetero-Bivalent Agents Targeting PSMA and Bone Metastases for Radionuclide Therapy

New PSMA-Targeting Ligands: Transformation from Diagnosis (Ga-68) to Radionuclide Therapy (Lu-177)

Synthesis and Evaluation of 68Ga- and 177Lu-Labeled (R)- vs (S)‑DOTAGA Prostate-Specific Membrane Antigen-Targeting Derivatives

Radiolabeling Optimization and Preclinical Evaluation of the New PSMA Imaging Agent [18F]AlF-P16-093

(68)Ga-Bivalent Polypegylated Styrylpyridine Conjugates for Imaging Aβ Plaques in Cerebral Amyloid Angiopathy

Preclinical evaluation of [18F]D3FSP, deuterated AV-45, for imaging of β-amyloid in the brain

Synthesis and evaluation of a novel urea-based 68Ga-complex for imaging PSMA binding in tumor

A New [68Ga]Ga-HBED-CC-Bisphosphonate as a Bone Imaging Agent

Expanding the Scope of Fluorine Tags for PET Imaging

[68Ga]Ga-HBED-CC-FAPI derivatives with improved radiolabeling and specific tumor uptake

Optimization of solid phase extraction (SPE) in preparation of D3-[18F]FSP: A new PET imaging agent for mapping Aβ plaques

Kit-based preparation of [68Ga]Ga-P16-093 (PSMA-093) using different commercial 68Ge/68Ga generators

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