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Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms

Frontiers in oncology, 2023-10, Vol.13, p.1223199-1223199

2023

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BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas

Clinical cancer research, 2016-11, Vol.22 (21), p.5312-5321

2016

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Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Nature communications, 2018-08, Vol.9 (1), p.2862-15, Article 2862

2018

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Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (24), p.5355-5366

2015

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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Cell reports (Cambridge), 2022-02, Vol.38 (7), p.110375-110375, Article 110375

2022

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Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

Oncotarget, 2016-11, Vol.7 (46), p.75839-75853

2016

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Regulation of Asymmetric Cell Division in Mammalian Neural Stem and Cancer Precursor Cells

Asymmetric Cell Division in Development, Differentiation and Cancer, 2017-01, Vol.61, p.375-399

2017

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Abstract 916: Asymmetric cell division regulator prevents hyperproliferation in glioma cell-of-origin

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.916-916

2017

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LGG-05. GENERATION OF NOVEL MOUSE MODELS FOR BRAF V600E MUTANT GLIOMAGENESIS TO GAIN MECHANISTIC INSIGHTS INTO TUMOR FORMATION AND PROGRESSION

Neuro-oncology (Charlottesville, Va.), 2021-06, Vol.23 (Supplement_1), p.i32-i32

2021

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Successes and challenges in modeling heterogeneous BRAF V600E mutated central nervous system neoplasms

Frontiers in oncology, 2023, Vol.13, p.1223199

2023

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Abstract 3072: Clinically relevant MAPK pathway inhibition reverses stem cell fate defects and sensitize BRAF mutant glioma to immune modulatory therapies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.3072-3072

2021

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Abstract 149: Tumor suppression by regulator of asymmetric cell division in glioma

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.149-149

2018

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Abstract 143: MAPK pathway blockade effects on glioma stem cells and immunotherapy in BRAFV600E mutant gliomas

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.143-143

2018

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BIOL-20. BIOPROCESSING OF SURGICAL PEDIATRIC BRAIN TUMOR SPECIMENS FOR GENOME-GUIDED PERSONALIZED DRUG TESTING

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i10-i10

2023

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TMOD-04. DETERMINING THE NEUROANATOMICAL AND CELLULAR ORIGIN OF BRAFV600E MUTANT CDKN2A DELETED GLIOMAS AND MECHANISMS OF TRANSFORMATION BY BRAFV600E EXPRESSION IN TRANSGENIC MICE

Neuro-oncology (Charlottesville, Va.), 2019-04, Vol.21 (Supplement_2), p.ii122-ii122

2019

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BSBM-17 NOVEL VALIDATED PATIENT-DERIVED MODELS OF A RECTAL CANCER BRAIN METASTASIS

Neuro-oncology advances, 2023-08, Vol.5 (Supplement_3), p.iii4-iii4

2023

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IMST-20. MAPK PATHWAY BLOCKADE PRIMES BRAFV600E MUTANT GLIOMA FOR IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2016-11, Vol.18 (suppl_6), p.vi90-vi90

2016

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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

BMC medicine, 2008-06, Vol.6 (1), p.14-14, Article 14

2008

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HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

Cancer cell, 2008-03, Vol.13 (3), p.206-220

2008

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STEM- AND PROGENITOR-LIKE CELL CONTRIBUTION TO MALIGNANT ASTROCYTOMA HETEROGENEITY

Neuro-oncology (Charlottesville, Va.), 2014-07, Vol.16 (suppl 3), p.iii21-iii21

2014

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Cell Cycle Regulation of p70 S6 Kinase and p42/p44 Mitogen-activated Protein Kinases in Swiss Mouse 3T3 Fibroblasts (∗)

The Journal of biological chemistry, 1996-01, Vol.271 (2), p.963-971

1996

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The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals

Mechanisms of development, 2005-07, Vol.122 (7), p.914-927

2005

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High efficiency polymer photodiodes

Synthetic metals, 1999-06, Vol.102 (1), p.957-958

1999

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Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms

BRAF Status in Personalizing Treatment Approaches for Pediatric Gliomas

Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium

LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model

Regulation of Asymmetric Cell Division in Mammalian Neural Stem and Cancer Precursor Cells

Abstract 916: Asymmetric cell division regulator prevents hyperproliferation in glioma cell-of-origin

LGG-05. GENERATION OF NOVEL MOUSE MODELS FOR BRAF V600E MUTANT GLIOMAGENESIS TO GAIN MECHANISTIC INSIGHTS INTO TUMOR FORMATION AND PROGRESSION

Successes and challenges in modeling heterogeneous BRAF V600E mutated central nervous system neoplasms

Abstract 3072: Clinically relevant MAPK pathway inhibition reverses stem cell fate defects and sensitize BRAF mutant glioma to immune modulatory therapies

Abstract 149: Tumor suppression by regulator of asymmetric cell division in glioma

Abstract 143: MAPK pathway blockade effects on glioma stem cells and immunotherapy in BRAFV600E mutant gliomas

BIOL-20. BIOPROCESSING OF SURGICAL PEDIATRIC BRAIN TUMOR SPECIMENS FOR GENOME-GUIDED PERSONALIZED DRUG TESTING

TMOD-04. DETERMINING THE NEUROANATOMICAL AND CELLULAR ORIGIN OF BRAFV600E MUTANT CDKN2A DELETED GLIOMAS AND MECHANISMS OF TRANSFORMATION BY BRAFV600E EXPRESSION IN TRANSGENIC MICE

BSBM-17 NOVEL VALIDATED PATIENT-DERIVED MODELS OF A RECTAL CANCER BRAIN METASTASIS

IMST-20. MAPK PATHWAY BLOCKADE PRIMES BRAFV600E MUTANT GLIOMA FOR IMMUNOTHERAPY

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

STEM- AND PROGENITOR-LIKE CELL CONTRIBUTION TO MALIGNANT ASTROCYTOMA HETEROGENEITY

Cell Cycle Regulation of p70 S6 Kinase and p42/p44 Mitogen-activated Protein Kinases in Swiss Mouse 3T3 Fibroblasts (∗)

The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals

High efficiency polymer photodiodes

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