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Group sequential designs for pragmatic clinical trials with early outcomes: methods and guidance for planning and implementation

BMC medical research methodology, 2024-02, Vol.24 (1), p.42-42

2024

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Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs

BMC medical research methodology, 2022-10, Vol.22 (1), p.256-256, Article 256

2022

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UK DRAFFT: a randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius

Health technology assessment (Winchester, England), 2015-02, Vol.19 (17), p.1-124

2015

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Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT

Health technology assessment (Winchester, England), 2018-05, Vol.22 (25), p.1-148

2018

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Plaster cast versus functional bracing for Achilles tendon rupture: the UKSTAR RCT

Health technology assessment (Winchester, England), 2020-02, Vol.24 (8), p.1-86

2020

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Unit of analysis issues in laboratory-based research

eLife, 2018-01, Vol.7

2018

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An evaluation of the quality of statistical design and analysis of published medical research: results from a systematic survey of general orthopaedic journals

BMC medical research methodology, 2012-04, Vol.12 (1), p.60-60, Article 60

2012

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Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2017-11, Vol.318 (18), p.1767

2017

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Five-year outcomes for patients sustaining severe fractures of the lower limb : mid-term results from the Wound management for Open Lower Limb Fracture (WOLLF) trial

The bone & joint journal, 2022-05, Vol.104-B (5), p.633

2022

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Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2018-06, Vol.319 (22), p.2280

2018

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Interventions for treating fractures of the distal femur in adults

Cochrane database of systematic reviews, 2022-10, Vol.10 (10), p.CD010606-CD010606

2022

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Differences in Microbial Activity and Microbial Populations of Peat Associated with Suppression of Damping-Off Disease Caused by Pythium sylvaticum

Applied and Environmental Microbiology, 2006-10, Vol.72 (10), p.6452-6460

2006

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Proportional-odds models for repeated composite and long ordinal outcome scales

Statistics in medicine, 2013-08, Vol.32 (18), p.3181-3191

Parsons, Nick R.

2013

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The comprehensive cohort model in a pilot trial in orthopaedic trauma

BMC medical research methodology, 2011-04, Vol.11 (1), p.39-39, Article 39

2011

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UK DRAFFT - a randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius

BMC musculoskeletal disorders, 2011-09, Vol.12 (1), p.201-201, Article 201

2011

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A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint

BMC musculoskeletal disorders, 2010-01, Vol.11 (1), p.8-8, Article 8

2010

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Percutaneous fixation with Kirschner wires versus volar locking plate fixation in adults with dorsally displaced fracture of distal radius: randomised controlled trial

BMJ (Online), 2014-08, Vol.349, p.g4807

2014

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Interpreting and reporting fracture classification and operation type in hip fracture: implications for research studies and routine national audits

The bone & joint journal, 2019-10, Vol.101-B (10), p.1292

2019

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Protocol for a randomised controlled trial of standard wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb: UK Wound management of Open Lower Limb Fractures (UK WOLFF)

BMJ open, 2015-01, Vol.5 (9), p.e009087

2015

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Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R

Computational statistics & data analysis, 2009-01, Vol.53 (3), p.632-641

2009

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A Comparison of Harris and Oxford Hip Scores for Assessing Outcome after Resurfacing Arthroplasty of the Hip: Can the Patient Tell us Everything we Need to Know?

Hip international, 2010-10, Vol.20 (4), p.453-459

2010

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Cast versus functional brace in the rehabilitation of patients treated non-operatively for a rupture of the Achilles tendon: protocol for the UK study of tendo achilles rehabilitation (UK STAR) multi-centre randomised trial

BMJ open, 2017-10, Vol.7 (10), p.e019628-e019628

2017

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Variation in microbial communities colonizing horticultural slow sand filter beds: implications for filter function

Irrigation science, 2013-07, Vol.31 (4), p.631-642

2013

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The PAT randomized clinical trial

The bone & joint journal, 2020-03, Vol.102-B (3), p.310

2020

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Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial

The Lancet (British edition), 2018-06, Vol.391 (10136), p.2225-2235

2018

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Group sequential designs for pragmatic clinical trials with early outcomes: methods and guidance for planning and implementation

Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs

UK DRAFFT: a randomised controlled trial of percutaneous fixation with Kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius

Intramedullary nail fixation versus locking plate fixation for adults with a fracture of the distal tibia: the UK FixDT RCT

Plaster cast versus functional bracing for Achilles tendon rupture: the UKSTAR RCT

Unit of analysis issues in laboratory-based research

An evaluation of the quality of statistical design and analysis of published medical research: results from a systematic survey of general orthopaedic journals

Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Trial

Five-year outcomes for patients sustaining severe fractures of the lower limb : mid-term results from the Wound management for Open Lower Limb Fracture (WOLLF) trial

Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial

Interventions for treating fractures of the distal femur in adults

Differences in Microbial Activity and Microbial Populations of Peat Associated with Suppression of Damping-Off Disease Caused by Pythium sylvaticum

Proportional-odds models for repeated composite and long ordinal outcome scales

The comprehensive cohort model in a pilot trial in orthopaedic trauma

UK DRAFFT - a randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius

A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint

Percutaneous fixation with Kirschner wires versus volar locking plate fixation in adults with dorsally displaced fracture of distal radius: randomised controlled trial

Interpreting and reporting fracture classification and operation type in hip fracture: implications for research studies and routine national audits

Protocol for a randomised controlled trial of standard wound management versus negative pressure wound therapy in the treatment of adult patients with an open fracture of the lower limb: UK Wound management of Open Lower Limb Fractures (UK WOLFF)

Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R

A Comparison of Harris and Oxford Hip Scores for Assessing Outcome after Resurfacing Arthroplasty of the Hip: Can the Patient Tell us Everything we Need to Know?

Cast versus functional brace in the rehabilitation of patients treated non-operatively for a rupture of the Achilles tendon: protocol for the UK study of tendo achilles rehabilitation (UK STAR) multi-centre randomised trial

Variation in microbial communities colonizing horticultural slow sand filter beds: implications for filter function

The PAT randomized clinical trial

Hip arthroscopy versus best conservative care for the treatment of femoroacetabular impingement syndrome (UK FASHIoN): a multicentre randomised controlled trial

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