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Genetics of Monogenic Diabetes: Present Clinical Challenges

Current diabetes reports, 2018-12, Vol.18 (12), p.141-11, Article 141

2018

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Monogenic diabetes in adults: what are the new developments?

Current opinion in genetics & development, 2018-06, Vol.50, p.103-110

Owen, Katharine R

2018

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Treating young adults with type 2 diabetes or monogenic diabetes

Best Practice & Research Clinical Endocrinology & Metabolism, 2016-06, Vol.30 (3), p.455-467

Owen, Katharine R., BSc, MD, FRCP

2016

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High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

Diabetes care, 2011-08, Vol.34 (8), p.1860-1862

2011

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Assessment of High-Sensitivity C-Reactive Protein Levels as Diagnostic Discriminator of Maturity-Onset Diabetes of the Young Due to HNF1A Mutations

Diabetes care, 2010-09, Vol.33 (9), p.1919-1924

2010

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First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

BMC medicine, 2023-05, Vol.21 (1), p.190-190

2023

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

PLoS medicine, 2006-10, Vol.3 (10), p.e374-e374

2006

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Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

Diabetes (New York, N.Y.), 2003-02, Vol.52 (2), p.568-572

2003

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Diagnosis and management of maturity onset diabetes of the young (MODY)

BMJ (Online), 2011-10, Vol.343 (7828), p.d6044

International edition, 2011

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Lipoprotein composition in HNF1A-MODY: Differentiating between HNF1A-MODY and Type 2 diabetes

Clinica chimica acta, 2012-05, Vol.413 (9-10), p.927-932

2012

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miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

Journal of molecular medicine (Berlin, Germany), 2015-10, Vol.93 (10), p.1159-1169

2015

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Traditional clinical criteria outperform high-sensitivity C-reactive protein for the screening of hepatic nuclear factor 1 alpha maturity-onset diabetes of the young among young Asians with diabetes

Therapeutic advances in endocrinology and metabolism, 2018-09, Vol.9 (9), p.271-282

2018

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Lixisenatide in type 1 diabetes: A randomised control trial of the effect of lixisenatide on post‐meal glucose excursions and glucagon in type 1 diabetes patients

Endocrinology, diabetes & metabolism, 2020-07, Vol.3 (3), p.e00130-n/a

2020

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Evaluation of Serum 1,5 Anhydroglucitol Levels as a Clinical Test to Differentiate Subtypes of Diabetes

Diabetes care, 2010-02, Vol.33 (2), p.252-257

2010

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Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers

PloS one, 2012-07, Vol.7 (7), p.e40962-e40962

2012

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Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in young adults

Diagnostic and prognostic research, 2020-06, Vol.4 (1), p.6-6, Article 6

2020

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Monogenic diabetes: old and new approaches to diagnosis

Clinical medicine (London, England), 2013-06, Vol.13 (3), p.278-281

Owen, Katharine R

2013

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Systematic Assessment of Etiology in Adults With a Clinical Diagnosis of Young-Onset Type 2 Diabetes Is a Successful Strategy for Identifying Maturity-Onset Diabetes of the Young

Diabetes care, 2012-06, Vol.35 (6), p.1206-1212

2012

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281-OR: Type 2 Diabetes Diagnosed between 16-30 Years in South Asian and White Individuals Is Phenotypically Similar

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes

Diabetes care, 2019-01, Vol.42 (1), p.17-26

2019

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When to consider a diagnosis of MODY at the presentation of diabetes: aetiology matters for correct management

British journal of general practice, 2016-06, Vol.66 (647), p.e457-e459

2016

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Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Science (American Association for the Advancement of Science), 2007-05, Vol.316 (5826), p.889-894

2007

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Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

Science (American Association for the Advancement of Science), 2007-06, Vol.316 (5829), p.1336-1341

2007

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Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population

Diabetes (New York, N.Y.), 2004-11, Vol.53 (11), p.3002-3006

2004

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Finding the needle in the haystack: how to identify monogenic diabetes in the paediatric clinic

Paediatrics and child health, 2022-01, Vol.32 (1), p.31-36

2022

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Genetics of Monogenic Diabetes: Present Clinical Challenges

Monogenic diabetes in adults: what are the new developments?

Treating young adults with type 2 diabetes or monogenic diabetes

High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes

Assessment of High-Sensitivity C-Reactive Protein Levels as Diagnostic Discriminator of Maturity-Onset Diabetes of the Young Due to HNF1A Mutations

First-in-human, double-blind, randomized phase 1b study of peptide immunotherapy IMCY-0098 in new-onset type 1 diabetes

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

Diagnosis and management of maturity onset diabetes of the young (MODY)

Lipoprotein composition in HNF1A-MODY: Differentiating between HNF1A-MODY and Type 2 diabetes

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

Traditional clinical criteria outperform high-sensitivity C-reactive protein for the screening of hepatic nuclear factor 1 alpha maturity-onset diabetes of the young among young Asians with diabetes

Lixisenatide in type 1 diabetes: A randomised control trial of the effect of lixisenatide on post‐meal glucose excursions and glucagon in type 1 diabetes patients

Evaluation of Serum 1,5 Anhydroglucitol Levels as a Clinical Test to Differentiate Subtypes of Diabetes

Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers

Logistic regression has similar performance to optimised machine learning algorithms in a clinical setting: application to the discrimination between type 1 and type 2 diabetes in young adults

Monogenic diabetes: old and new approaches to diagnosis

Systematic Assessment of Etiology in Adults With a Clinical Diagnosis of Young-Onset Type 2 Diabetes Is a Successful Strategy for Identifying Maturity-Onset Diabetes of the Young

281-OR: Type 2 Diabetes Diagnosed between 16-30 Years in South Asian and White Individuals Is Phenotypically Similar

Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes

When to consider a diagnosis of MODY at the presentation of diabetes: aetiology matters for correct management

Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes

Common Variants of the Hepatocyte Nuclear Factor-4α P2 Promoter Are Associated With Type 2 Diabetes in the U.K. Population

Finding the needle in the haystack: how to identify monogenic diabetes in the paediatric clinic

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