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A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

Nature communications, 2022-04, Vol.13 (1), p.2206-2206, Article 2206

2022

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Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Nature cell biology, 2020-04, Vol.22 (4), p.476

2020

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Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite

PLoS pathogens, 2010-10, Vol.6 (10), p.e1001165-e1001165

2010

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Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism

PLoS genetics, 2014-01, Vol.10 (1), p.e1004085-e1004085

2014

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NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation

Genes & diseases, 2021-11, Vol.8 (6), p.731-745

2021

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Central carbon metabolism of Plasmodium parasites

Molecular and biochemical parasitology, 2011-02, Vol.175 (2), p.95-103

2011

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Host-parasite interactions revealed by Plasmodium falciparum metabolomics

Cell host & microbe, 2009-02, Vol.5 (2), p.191-199

2009

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Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii

International journal for parasitology, 2018-10, Vol.48 (12), p.955-968

2018

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Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network

Molecular systems biology, 2010-09, Vol.6 (1), p.408-n/a

2010

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SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells

Nature communications, 2023-06, Vol.14 (1), p.3673-3673, Article 3673

2023

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Branched tricarboxylic acid metabolism in Plasmodium falciparum

Nature, 2010-08, Vol.466 (7307), p.774-778

2010

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Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance

Nature communications, 2024-01, Vol.15 (1), p.79-79, Article 79

2024

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Specific DNA-binding by Apicomplexan AP2 transcription factors

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (24), p.8393-8398

2008

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Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system

Genome biology, 2007-07, Vol.8 (7), p.R135-R135, Article R135

2007

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Thiol profiling in cancer cell lines by HPLC-mass spectrometry

STAR protocols, 2021-12, Vol.2 (4), p.100977-100977, Article 100977

2021

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Nearest Neighbor Networks: clustering expression data based on gene neighborhoods

BMC bioinformatics, 2007-07, Vol.8 (1), p.250-250, Article 250

2007

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Co-inhibition of Plasmodium falciparum S-Adenosylmethionine Decarboxylase/Ornithine Decarboxylase Reveals Perturbation-specific Compensatory Mechanisms by Transcriptome, Proteome, and Metabolome Analyses

The Journal of biological chemistry, 2009-02, Vol.284 (7), p.4635-4646

2009

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A gene expression fingerprint of C. elegans embryonic motor neurons

BMC genomics, 2005-03, Vol.6 (1), p.42-42, Article 42

2005

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KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition

iScience, 2021-06, Vol.24 (6), p.102649, Article 102649

2021

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Crystal Structure of Arginase from Plasmodium falciparum and Implications for l-Arginine Depletion in Malarial Infection

Biochemistry (Easton), 2010-07, Vol.49 (26), p.5600-5608

2010

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Extraction of hydrophilic metabolites from Plasmodium falciparum-infected erythrocytes for metabolomic analysis

Methods in molecular biology (Clifton, N.J.), 2013, Vol.923, p.259

2013

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Quantitative determination of urea concentrations in cell culture medium

Biochemistry and cell biology, 2009-06, Vol.87 (3), p.541

2009

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DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Nature (London), 2021-05, Vol.593 (7860), p.586-590

2021

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Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum

Nature (London), 2013-05, Vol.497 (7451), p.652-652

2013

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Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition

Nature (London), 2023-07, Vol.619 (7968), p.E19-E23

2023

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A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite

Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism

NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation

Central carbon metabolism of Plasmodium parasites

Host-parasite interactions revealed by Plasmodium falciparum metabolomics

Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii

Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network

SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells

Branched tricarboxylic acid metabolism in Plasmodium falciparum

Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance

Specific DNA-binding by Apicomplexan AP2 transcription factors

Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system

Thiol profiling in cancer cell lines by HPLC-mass spectrometry

Nearest Neighbor Networks: clustering expression data based on gene neighborhoods

Co-inhibition of Plasmodium falciparum S-Adenosylmethionine Decarboxylase/Ornithine Decarboxylase Reveals Perturbation-specific Compensatory Mechanisms by Transcriptome, Proteome, and Metabolome Analyses

A gene expression fingerprint of C. elegans embryonic motor neurons

KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition

Crystal Structure of Arginase from Plasmodium falciparum and Implications for l-Arginine Depletion in Malarial Infection

Extraction of hydrophilic metabolites from Plasmodium falciparum-infected erythrocytes for metabolomic analysis

Quantitative determination of urea concentrations in cell culture medium

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum

Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition

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