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Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Frontiers in aging neuroscience, 2018-07, Vol.10, p.199-199

2018

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Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

The Journal of neuroscience, 2012-11, Vol.32 (46), p.16129-16140

2012

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Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice

Neurobiology of disease, 2017-06, Vol.102, p.81-95

2017

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Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

The Journal of neuroscience, 2016-02, Vol.36 (5), p.1502-1515

2016

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Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease

Frontiers in aging neuroscience, 2018-09, Vol.10, p.287-287

2018

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The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss

PloS one, 2016-05, Vol.11 (5), p.e0154721-e0154721

2016

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Is It Time to Repurpose Calcineurin Inhibitors for the Treatment of Cognitive Impairment and Dementia?

Journal of Alzheimer's disease, 2023-01, Vol.95 (2), p.599-602

Norris, Christopher M

2023

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Alzheimer's diseases in America, Europe, and Asian regions: a global genetic variation

PeerJ (San Francisco, CA), 2024-05, Vol.12, p.e17339, Article e17339

2024

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Back Rehabilitation: Core Stability Re-examined

Norris, Christopher M.

3rd Edition, 2023

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Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer's disease mouse model

Frontiers in cellular neuroscience, 2023-03, Vol.17, p.895017-895017

2023

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Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer’s disease

Ageing research reviews, 2021-07, Vol.68, p.101335-101335, Article 101335

2021

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Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

PloS one, 2012-05, Vol.7 (5), p.e38170

2012

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Calcineurin Triggers Reactive/Inflammatory Processes in Astrocytes and Is Upregulated in Aging and Alzheimer's Models

The Journal of neuroscience, 2005-05, Vol.25 (18), p.4649-4658

2005

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Calcineurin: directing the damage in Alzheimer disease: An Editorial for 'Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain' on page 24

Journal of neurochemistry, 2018-10, Vol.147 (1), p.8-11

Norris, Christopher M

2018

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Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

Journal of visualized experiments, 2011-03 (49)

2011

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Brain–Blood Partition Coefficient and Cerebral Blood Flow in Canines Using Calibrated Short TR Recovery (CaSTRR) Correction Method

Frontiers in neuroscience, 2019-11, Vol.13, p.1189-1189

2019

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Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons

The Journal of neuroscience, 2011-02, Vol.31 (5), p.1693-1703

2011

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Calcineurin: directing the damage in Alzheimer disease

Journal of neurochemistry, 2018-10, Vol.147 (1), p.8-11

Norris, Christopher M.

2018

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Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia

ASN neuro, 2019-07, Vol.11, p.1759091419865788-1759091419865788

2019

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An emerging role of astrocytes in vascular contributions to cognitive impairment and dementia

Journal of neurochemistry, 2018-03, Vol.144 (5), p.644-650

2018

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Calcineurin and glial signaling: neuroinflammation and beyond

Journal of neuroinflammation, 2014-09, Vol.11 (1), p.158-158, Article 158

2014

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Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction

Ageing research reviews, 2013-09, Vol.12 (4), p.982-995

2013

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Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture

Aging cell, 2011-02, Vol.10 (1), p.103-113

2011

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Locomotor performance differs between foraging and predator escape but is not related to survival in hatchling lizards

Biological journal of the Linnean Society, 2024-01, Vol.141 (1), p.102-117

2024

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Elevated calcineurin activity in primary astrocytes leads to the dephosphorylation of connexin 43 in conjunction with increased membrane permeability

Neuroreport, 2024-07, Vol.35 (10), p.673-678

2024

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Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice

Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease

The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss

Is It Time to Repurpose Calcineurin Inhibitors for the Treatment of Cognitive Impairment and Dementia?

Alzheimer's diseases in America, Europe, and Asian regions: a global genetic variation

Back Rehabilitation: Core Stability Re-examined

Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer's disease mouse model

Reactive astrocytes: The nexus of pathological and clinical hallmarks of Alzheimer’s disease

Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

Calcineurin Triggers Reactive/Inflammatory Processes in Astrocytes and Is Upregulated in Aging and Alzheimer's Models

Calcineurin: directing the damage in Alzheimer disease: An Editorial for 'Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain' on page 24

Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

Brain–Blood Partition Coefficient and Cerebral Blood Flow in Canines Using Calibrated Short TR Recovery (CaSTRR) Correction Method

Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons

Calcineurin: directing the damage in Alzheimer disease

Blood Flow Deficits and Cerebrovascular Changes in a Dietary Model of Hyperhomocysteinemia

An emerging role of astrocytes in vascular contributions to cognitive impairment and dementia

Calcineurin and glial signaling: neuroinflammation and beyond

Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction

Proteolysis of calcineurin is increased in human hippocampus during mild cognitive impairment and is stimulated by oligomeric Abeta in primary cell culture

Locomotor performance differs between foraging and predator escape but is not related to survival in hatchling lizards

Elevated calcineurin activity in primary astrocytes leads to the dephosphorylation of connexin 43 in conjunction with increased membrane permeability

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