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Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

The Journal of immunology (1950), 2014-03, Vol.192 (6), p.2837-2845

2014

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Complement receptor CD46 co-stimulates optimal human CD8 + T cell effector function via fatty acid metabolism

Nature communications, 2018-10, Vol.9 (1), p.4186-15, Article 4186

2018

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Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation

The Journal of immunology (1950), 2017-10, Vol.199 (8), p.2910-2920

2017

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Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

The Journal of immunology (1950), 2016-06, Vol.196 (12), p.5064-5074

2016

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Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis

EBioMedicine, 2020-10, Vol.60, p.102985-102985, Article 102985

2020

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Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation

The Journal of immunology (1950), 2015-07, Vol.195 (1), p.257-264

2015

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Complement's favourite organelle—Mitochondria?

British journal of pharmacology, 2021-07, Vol.178 (14), p.2771-2785

2021

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Complement activation by cholesterol crystals triggers a subsequent cytokine response

Molecular immunology, 2017-04, Vol.84, p.43-50

2017

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Cholesterol crystals use both extracellular and intracellular complement to increase NLRP3 signalling pathways in atherosclerosis

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.146-146.4

2020

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T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.150-150.23

2020

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Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF

Immunobiology (1979), 2014-10, Vol.219 (10), p.786-792

2014

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SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.125-125.39

2022

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The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.75-75.8

2017

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The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Molecular immunology, 2017-09, Vol.89, p.131-131

2017

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Complement receptor CD46 is a key co-stimulator for optimal human CD8+ T cell effector function

Molecular immunology, 2018-10, Vol.102, p.172-172

2018

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Auto-regulation of Th1 responses requires intracellular carboxypeptidase M-mediated complement regulation

Molecular immunology, 2018-10, Vol.102, p.228-228

2018

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Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

Molecular immunology, 2017-09, Vol.89, p.135-135

2017

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Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis

Molecular immunology, 2017-09, Vol.89, p.125-126

2017

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Cyclodextrin inhibits CC-induced complement activation

Molecular immunology, 2017-09, Vol.89, p.167-168

2017

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The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Immunobiology (1979), 2016-10, Vol.221 (10), p.1179-1179

2016

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Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

Immunobiology (1979), 2016-10, Vol.221 (10), p.1178-1178

2016

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Cholesterol crystals activate the lectin complement pathway via ficolin-2 and MBL – Implications for the progression of atherosclerosis

Immunobiology (1979), 2016-10, Vol.221 (10), p.1138-1138

2016

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Complement dependency of cholesterol crystal-induced inflammation – II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP)

Immunobiology (1979), 2012-11, Vol.217 (11), p.1157-1157

2012

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Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

Complement receptor CD46 co-stimulates optimal human CD8 + T cell effector function via fatty acid metabolism

Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis

Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis

Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation

Complement's favourite organelle—Mitochondria?

Complement activation by cholesterol crystals triggers a subsequent cytokine response

Cholesterol crystals use both extracellular and intracellular complement to increase NLRP3 signalling pathways in atherosclerosis

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

T cell-intrinsic C5L2 activation protects against uncontrolled inflammatory Th responses and autoimmunity

Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation

Complement receptor CD46 is a key co-stimulator for optimal human CD8+ T cell effector function

Auto-regulation of Th1 responses requires intracellular carboxypeptidase M-mediated complement regulation

Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis

Cyclodextrin inhibits CC-induced complement activation

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

Cholesterol crystals activate the lectin complement pathway via ficolin-2 and MBL – Implications for the progression of atherosclerosis

Complement dependency of cholesterol crystal-induced inflammation – II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP)

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