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A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

The American heart journal, 2007, Vol.153 (1), p.66.e9-66.e16

2007

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Comparison of Speed of Onset of Platelet Inhibition After Loading Doses of Clopidogrel Versus Prasugrel in Healthy Volunteers and Correlation With Responder Status

The American journal of cardiology, 2007-07, Vol.100 (2), p.331-336

2007

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The Platelet Inhibitory Effects and Pharmacokinetics of Prasugrel After Administration of Loading and Maintenance Doses in Healthy Subjects

Journal of cardiovascular pharmacology, 2006-03, Vol.47 (3), p.377-384

2006

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Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A single ascending dose study in healthy humans

Platelets (Edinburgh), 2006-06, Vol.17 (4), p.209-217

2006

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Species differences in the transport activity for organic anions across the bile canalicular membrane

The Journal of pharmacology and experimental therapeutics, 1999-09, Vol.290 (3), p.1324

1999

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Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

European heart journal, 2006-05, Vol.27 (10), p.1166-1173

2006

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Panipenum, a carbapenem antibiotic, increases the level of hepatic UDP-glucuronic acid in rats

Drug metabolism and disposition, 2000-12, Vol.28 (12), p.1484

2000

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Panipenem, a carbapenem antibiotic, enhances the glucuronidation of intravenously administered valproic acid in rats

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.724

1999

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Prediction of Pharmacokinetics of Antibiotics in Patients with End-Stage Renal Disease

Biological and Pharmaceutical Bulletin, 2006, Vol.29(7), pp.1454-1459

2006

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Quantitative Evaluation of Effect of Renal Failure on the Pharmacokinetics of Panipenem in Rats

Biological and Pharmaceutical Bulletin, 2005, Vol.28(11), pp.2170-2172

2005

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Prasugrel: A Novel Thienopyridine Antiplatelet Agent. A Review of Preclinical and Clinical Studies and the Mechanistic Basis for Its Distinct Antiplatelet Profile

Cardiovascular drug reviews, 2007-12, Vol.25 (4), p.357-374

2007

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Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptide

The Journal of pharmacology and experimental therapeutics, 1998-10, Vol.287 (1), p.37

1998

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Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR)

The Journal of pharmacology and experimental therapeutics, 1997-03, Vol.280 (3), p.1304

1997

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A multiple dose study of prasugrel (CS‐747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans

British journal of clinical pharmacology, 2007-04, Vol.63 (4), p.421-430

2007

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Brain insulin impairs amyloid-beta(1-40) clearance from the brain

The Journal of neuroscience, 2004-10, Vol.24 (43), p.9632-9637

2004

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Trandolaprilat, an Angiotensin-Converting Enzyme Inhibitor, Is Not Excreted in Bile via an ATP-Dependent Active Transporter (cMOAT)

Hypertension Research, 2001, Vol.24(3), pp.235-240

2001

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Dose-Dependent Inhibition of Human Platelet Aggregation by Prasugrel and its Interaction With Aspirin in Healthy Subjects

Journal of cardiovascular pharmacology, 2007-03, Vol.49 (3), p.167-173

2007

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Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A multiple-dose study in healthy humans

Platelets (Edinburgh), 2006-06, Vol.17 (4), p.218-226

2006

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Population Pharmacokinetic Analysis of Panipenem/Betamipron in Patients with Various Degrees of Renal Function

Chemotherapy (Basel), 2006-01, Vol.52 (5), p.245-253

2006

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Greater Inhibition of Platelet Aggregation and Reduced Response Variability With Prasugrel Versus Clopidogrel: An Integrated Analysis

Journal of cardiovascular pharmacology and therapeutics, 2007-09, Vol.12 (3), p.205-212

2007

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A multiple dose study of prasugrel (CS‐747), a novel thienopyridine P2Y 12 inhibitor, compared with clopidogrel in healthy humans

British journal of clinical pharmacology, 2007-04, Vol.63 (4), p.421-430

2007

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Clopidogrel poor responders: An objective definition based on Bayesian classification

Platelets (Edinburgh), 2007-01, Vol.18 (6), p.428-435

2007

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3-Bromomethyl-7-methoxy-1,4-benzoxazin-2-one as a highly sensitive fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatography

Journal of Chromatography A, 1992-02, Vol.591 (1), p.159-164

1992

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Current status and issues of drug development strategy in Japan

Drug Delivery System, 2007, Vol.22(1), pp.65-72

2007

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Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y 12 inhibitor: A multiple-dose study in healthy humans

Platelets (Edinburgh), 2006-01, Vol.17 (4), p.218-226

2006

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A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

Comparison of Speed of Onset of Platelet Inhibition After Loading Doses of Clopidogrel Versus Prasugrel in Healthy Volunteers and Correlation With Responder Status

The Platelet Inhibitory Effects and Pharmacokinetics of Prasugrel After Administration of Loading and Maintenance Doses in Healthy Subjects

Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A single ascending dose study in healthy humans

Species differences in the transport activity for organic anions across the bile canalicular membrane

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Panipenum, a carbapenem antibiotic, increases the level of hepatic UDP-glucuronic acid in rats

Panipenem, a carbapenem antibiotic, enhances the glucuronidation of intravenously administered valproic acid in rats

Prediction of Pharmacokinetics of Antibiotics in Patients with End-Stage Renal Disease

Quantitative Evaluation of Effect of Renal Failure on the Pharmacokinetics of Panipenem in Rats

Prasugrel: A Novel Thienopyridine Antiplatelet Agent. A Review of Preclinical and Clinical Studies and the Mechanistic Basis for Its Distinct Antiplatelet Profile

Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptide

Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR)

A multiple dose study of prasugrel (CS‐747), a novel thienopyridine P2Y12 inhibitor, compared with clopidogrel in healthy humans

Brain insulin impairs amyloid-beta(1-40) clearance from the brain

Trandolaprilat, an Angiotensin-Converting Enzyme Inhibitor, Is Not Excreted in Bile via an ATP-Dependent Active Transporter (cMOAT)

Dose-Dependent Inhibition of Human Platelet Aggregation by Prasugrel and its Interaction With Aspirin in Healthy Subjects

Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y12 inhibitor: A multiple-dose study in healthy humans

Population Pharmacokinetic Analysis of Panipenem/Betamipron in Patients with Various Degrees of Renal Function

Greater Inhibition of Platelet Aggregation and Reduced Response Variability With Prasugrel Versus Clopidogrel: An Integrated Analysis

A multiple dose study of prasugrel (CS‐747), a novel thienopyridine P2Y 12 inhibitor, compared with clopidogrel in healthy humans

Clopidogrel poor responders: An objective definition based on Bayesian classification

3-Bromomethyl-7-methoxy-1,4-benzoxazin-2-one as a highly sensitive fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatography

Current status and issues of drug development strategy in Japan

Platelet inhibitory activity and pharmacokinetics of prasugrel (CS-747) a novel thienopyridine P2Y 12 inhibitor: A multiple-dose study in healthy humans

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