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The dual PI3 kinase mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML

Leukemia, 2008-09, Vol.22 (9), p.1728-1736

2008

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Eμ miR-125b transgenic mice develop lethal B-cell malignancies

Leukemia, 2011-12, Vol.25 (12), p.1849-1856

2011

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Pretreatment of leukemic cells with low-dose decitabine markedly enhances the cytotoxicity of gemtuzumab ozogamicin

Leukemia, 2013-01, Vol.27 (1), p.233-235

2013

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Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1 Noxa axis

Leukemia, 2010-01, Vol.24 (1), p.33-43

2010

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Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan

Medicine (Baltimore), 2004-05, Vol.83 (3), p.193-207

2004

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Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP

Blood, 2006-02, Vol.107 (3), p.1184-1191

2006

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PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor

Molecular biology of the cell, 2003-10, Vol.14 (10), p.4285-4295

2003

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Impaired Glycosylation of Glycosylphosphatidylinositol-Anchor Synthesis in Paroxysmal Nocturnal Hemoglobinuria Leukocytes

Biochemical and biophysical research communications, 1993-03, Vol.191 (2), p.571-579

1993

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Paroxysmal nocturnal hemoglobinuria--pathophysiological implication of altered glycosylation

Seikagaku. The Journal of Japanese Biochemical Society, 1994-02, Vol.66 (2), p.137

Nakakuma, H

1994

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Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1

Leukemia, 2010-01, Vol.24 (1), p.33

2010

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E[mu]/miR-125b transgenic mice develop lethal B-cell malignancies

Leukemia, 2011-12, Vol.25 (12), p.1849

2011

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Catalase (CAT)

Nihon rinshō, 1999-08, Vol.57 Suppl, p.496

1999

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Plasma protein

Nihon rinshō, 1999-08, Vol.57 Suppl, p.183

1999

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Apoptosis resistance of blood cells from patients with paroxysmal nocturnal hemoglobinuria, aplastic anemia, and myelodysplastic syndrome

Blood, 1997-10, Vol.90 (7), p.2716-2722

1997

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Pathogenesis of selective expansion of PNH clones

International journal of hematology, 2003-02, Vol.77 (2), p.121-124

2003

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Apoptosis Resistance of Blood Cells From Patients With Paroxysmal Nocturnal Hemoglobinuria, Aplastic Anemia, and Myelodysplastic Syndrome

Blood, 1997-10, Vol.90 (7), p.2716-2722

1997

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Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro

Blood, 2002-08, Vol.100 (3), p.1031-1037

2002

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Sequential development of myelodysplasia and paroxysmal nocturnal hemoglobinuria in a patient with preceding aplastic anemia

International journal of hematology, 1997-02, Vol.65 (2), p.187

1997

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Rarity of microsatellite alterations in patients with paroxysmal nocturnal haemoglobinuria

European journal of haematology, 2000-06, Vol.64 (6), p.430-432

2000

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Proposal for a classification of the clinical stages of paroxysmal nocturnal hemoglobinuria

Blood, 1995-09, Vol.86 (5), p.2051-2052

1995

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Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes

British journal of haematology, 1998-07, Vol.102 (2), p.465-474

1998

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Positivity of the sugar-water test in the screening for paroxysmal nocturnal hemoglobinuria

Blood, 1994-08, Vol.84 (4), p.1349-1349

1994

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Glycosylphosphatidylinositol-anchored proteins with complement-regulatory activity on erythrocytes

Nihon rinshō, 1996-09, Vol.54 (9), p.2370

1996

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The dual Pl3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML

Leukemia, 2008, Vol.22 (9), p.1728-1736

2008

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Mechanism of intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH)

American journal of hematology, 1996-09, Vol.53 (1), p.22-29

Nakakuma, Hideki

1996

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The dual PI3 kinase mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML

Eμ miR-125b transgenic mice develop lethal B-cell malignancies

Pretreatment of leukemic cells with low-dose decitabine markedly enhances the cytotoxicity of gemtuzumab ozogamicin

Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1 Noxa axis

Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan

Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP

PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor

Impaired Glycosylation of Glycosylphosphatidylinositol-Anchor Synthesis in Paroxysmal Nocturnal Hemoglobinuria Leukocytes

Paroxysmal nocturnal hemoglobinuria--pathophysiological implication of altered glycosylation

Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1

E[mu]/miR-125b transgenic mice develop lethal B-cell malignancies

Catalase (CAT)

Plasma protein

Apoptosis resistance of blood cells from patients with paroxysmal nocturnal hemoglobinuria, aplastic anemia, and myelodysplastic syndrome

Pathogenesis of selective expansion of PNH clones

Apoptosis Resistance of Blood Cells From Patients With Paroxysmal Nocturnal Hemoglobinuria, Aplastic Anemia, and Myelodysplastic Syndrome

Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro

Sequential development of myelodysplasia and paroxysmal nocturnal hemoglobinuria in a patient with preceding aplastic anemia

Rarity of microsatellite alterations in patients with paroxysmal nocturnal haemoglobinuria

Proposal for a classification of the clinical stages of paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes

Positivity of the sugar-water test in the screening for paroxysmal nocturnal hemoglobinuria

Glycosylphosphatidylinositol-anchored proteins with complement-regulatory activity on erythrocytes

The dual Pl3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML

Mechanism of intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH)

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