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Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury

Nature reviews. Nephrology, 2022-02, Vol.18 (2), p.95-112

2022

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Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design

Frontiers in immunology, 2022-05, Vol.13, p.867625-867625

2022

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Organotypic heterogeneity in microvascular endothelial cell responses in sepsis—a molecular treasure trove and pharmacological Gordian knot

Frontiers in medicine, 2023-11, Vol.10, p.1252021-1252021

2023

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Kidney histopathology in lethal human sepsis

Critical care (London, England), 2018-12, Vol.22 (1), p.359-359, Article 359

2018

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Identification of LPS-Activated Endothelial Subpopulations With Distinct Inflammatory Phenotypes and Regulatory Signaling Mechanisms

Frontiers in immunology, 2019-05, Vol.10, p.1169-1169

2019

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Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation

Pharmacological reviews, 2000-06, Vol.52 (2), p.237

2000

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Hyperglycaemic memory affects the neurovascular unit of the retina in a diabetic mouse model

Diabetologia, 2017-07, Vol.60 (7), p.1354-1358

2017

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Vascular Heterogeneity in the Kidney

Seminars in nephrology, 2012-03, Vol.32 (2), p.145-155

2012

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Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

The Journal of pathology, 2012-11, Vol.228 (3), p.378-390

2012

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A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

Nature communications, 2016-01, Vol.7 (1), p.10160-10160, Article 10160

2016

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Pharmacological inhibition of focal adhesion kinase 1 (FAK1) and anaplastic lymphoma kinase (ALK) identified via kinome profile analysis attenuates lipopolysaccharide-induced endothelial inflammatory activation

Biomedicine & pharmacotherapy, 2021-01, Vol.133, p.111073, Article 111073

2021

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Combining laser microdissection and microRNA expression profiling to unmask microRNA signatures in complex tissues

BioTechniques, 2019-12, Vol.67 (6), p.276-285

2019

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Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis

PloS one, 2013-07, Vol.8 (7), p.e68408-e68408

2013

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Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex

PloS one, 2023-11, Vol.18 (11), p.e0293673-e0293673

2023

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Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice

PloS one, 2022-06, Vol.17 (6), p.e0268986-e0268986

2022

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Streptococcus pneumoniae Interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor

PloS one, 2014-05, Vol.9 (5), p.e97914-e97914

2014

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Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass

PloS one, 2015-08, Vol.10 (8), p.e0136205-e0136205

2015

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Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System

PloS one, 2015-09, Vol.10 (9), p.e0138870-e0138870

2015

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Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro

Frontiers in pharmacology, 2022-12, Vol.13, p.992262-992262

2022

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Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia

PloS one, 2018-05, Vol.13 (5), p.e0196976-e0196976

2018

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Development of a Combined Lipid-Based Nanoparticle Formulation for Enhanced siRNA Delivery to Vascular Endothelial Cells

Pharmaceutics, 2022-09, Vol.14 (10), p.2086

2022

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Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

Cellular physiology and biochemistry, 2011, Vol.28 (1), p.125-136

2011

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Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia

Cells (Basel, Switzerland), 2023-07, Vol.12 (14), p.1850

2023

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Time course of the angiogenic response during normotrophic and hypertrophic scar formation in humans

Wound repair and regeneration, 2011-05, Vol.19 (3), p.292-301

2011

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Heterogeneity in endothelial responsiveness to cytokines, molecular causes, and pharmacological consequences

Seminars in thrombosis and hemostasis, 2010-04, Vol.36 (3), p.246

Molema, Grietje

2010

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Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury

Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design

Organotypic heterogeneity in microvascular endothelial cell responses in sepsis—a molecular treasure trove and pharmacological Gordian knot

Kidney histopathology in lethal human sepsis

Identification of LPS-Activated Endothelial Subpopulations With Distinct Inflammatory Phenotypes and Regulatory Signaling Mechanisms

Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation

Hyperglycaemic memory affects the neurovascular unit of the retina in a diabetic mouse model

Vascular Heterogeneity in the Kidney

Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization

A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

Pharmacological inhibition of focal adhesion kinase 1 (FAK1) and anaplastic lymphoma kinase (ALK) identified via kinome profile analysis attenuates lipopolysaccharide-induced endothelial inflammatory activation

Combining laser microdissection and microRNA expression profiling to unmask microRNA signatures in complex tissues

Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis

Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex

Pattern of tamoxifen-induced Tie2 deletion in endothelial cells in mature blood vessels using endo SCL-Cre-ERT transgenic mice

Streptococcus pneumoniae Interacts with pIgR expressed by the brain microvascular endothelium but does not co-localize with PAF receptor

Angiopoietin/Tie2 Dysbalance Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass

Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System

Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro

Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia

Development of a Combined Lipid-Based Nanoparticle Formulation for Enhanced siRNA Delivery to Vascular Endothelial Cells

Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

Reduced Tie2 in Microvascular Endothelial Cells Is Associated with Organ-Specific Adhesion Molecule Expression in Murine Health and Endotoxemia

Time course of the angiogenic response during normotrophic and hypertrophic scar formation in humans

Heterogeneity in endothelial responsiveness to cytokines, molecular causes, and pharmacological consequences

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