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Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators

Cell, 2018-06, Vol.173 (7), p.1650-1662.e14

2018

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An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options

Proceedings of the National Academy of Sciences - PNAS, 2023-02, Vol.120 (8), p.e2215945120-e2215945120

2023

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Transient Kinetic Analysis of Hydrogen Sulfide Oxidation Catalyzed by Human Sulfide Quinone Oxidoreductase

The Journal of biological chemistry, 2015-10, Vol.290 (41), p.25072-25080

2015

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Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

Journal of molecular biology, 2009-01, Vol.385 (4), p.1127-1141

2009

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The elemental mechanism of transcriptional pausing

eLife, 2019-01, Vol.8

2019

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Alkaline pH has an unexpected effect on transcriptional pausing during synthesis of the Escherichia coli pH-responsive riboswitch

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102302-102302, Article 102302

2022

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Phosphorylation and acetylation of mitochondrial transcription factor A promote transcription processivity without compromising initiation or DNA compaction

The Journal of biological chemistry, 2022-04, Vol.298 (4), p.101815-101815, Article 101815

2022

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Expression and Purification of Recombinant Human Mitochondrial RNA Polymerase (POLRMT) and the Initiation Factors TFAM and TFB2M

Bio-protocol, 2023-12, Vol.13 (23), p.e4892-e4892

2023

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Mechanisms of Transcriptional Pausing in Bacteria

Journal of molecular biology, 2019-09, Vol.431 (20), p.4007-4029

2019

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RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing

Molecular cell, 2018-03, Vol.69 (5), p.802-815.e5

2018

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Synthesis and application of isotopically labeled flavin nucleotides

Journal of labelled compounds & radiopharmaceuticals, 2015-07, Vol.58 (9), p.370-375

2015

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Acetylation and phosphorylation of mitochondrial transcription factor a promote mitochondrial transcription processivity

Biophysical journal, 2023-02, Vol.122 (3), p.492a-492a

2023

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Exploring the mechanisms behind the E. coli pH-responsive riboswitch

Biophysical journal, 2023-02, Vol.122 (3), p.149a-149a

2023

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Conserved Trigger Loop Histidine of RNA Polymerase II Functions as a Positional Catalyst Primarily through Steric Effects

Biochemistry (Easton), 2021-11, Vol.60 (44), p.3323-3336

2021

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Trigger loop of RNA polymerase is a positional, not acid–base, catalyst for both transcription and proofreading

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (26), p.E5103-E5112

2017

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Mechanisms and inhibition of uracil methylating enzymes

Bioorganic chemistry, 2012-08, Vol.43, p.37-43

2012

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An unprecedented mechanism of nucleotide methylation in organisms containing thyX

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6272), p.507-510

2016

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Substrate Activation in Flavin-Dependent Thymidylate Synthase

Journal of the American Chemical Society, 2014-07, Vol.136 (30), p.10597-10600

2014

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Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

Nature chemical biology, 2015-07, Vol.11 (7), p.457

2015

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Chemical quenching and identification of intermediates in flavoenzyme-catalyzed reactions

Methods in enzymology, 2019, Vol.620, p.89

2019

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Trapping of an Intermediate in the Reaction Catalyzed by Flavin-Dependent Thymidylate Synthase

Journal of the American Chemical Society, 2012-03, Vol.134 (9), p.4442-4448

2012

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Structural and mechanistic study of a pH-responsive riboswitch

Biophysical journal, 2022-02, Vol.121 (3), p.205a-205a

2022

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Conserved mechanisms of transcriptional pausing regulate diverse RNA polymerases

The FASEB journal, 2019-04, Vol.33 (S1), p.624.2-624.2

2019

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Accurate Measurement of Methyl 13C Chemical Shifts by Solid-State NMR for the Determination of Protein Side Chain Conformation: The Influenza A M2 Transmembrane Peptide as an Example

Journal of the American Chemical Society, 2009-06, Vol.131 (22), p.7806-7816

2009

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Accurate Measurement of Methyl 13C Chemical Shifts by Solid-State NMR for the Determination of Protein Sidechain Conformation: the Influenza A M2 Transmembrane Peptide as an Example

Journal of the American Chemical Society, 2009-06, Vol.131 (22), p.7806-7816

2009

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Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators

An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options

Transient Kinetic Analysis of Hydrogen Sulfide Oxidation Catalyzed by Human Sulfide Quinone Oxidoreductase

Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: The Role of Ser31 in Amantadine Binding

The elemental mechanism of transcriptional pausing

Alkaline pH has an unexpected effect on transcriptional pausing during synthesis of the Escherichia coli pH-responsive riboswitch

Phosphorylation and acetylation of mitochondrial transcription factor A promote transcription processivity without compromising initiation or DNA compaction

Expression and Purification of Recombinant Human Mitochondrial RNA Polymerase (POLRMT) and the Initiation Factors TFAM and TFB2M

Mechanisms of Transcriptional Pausing in Bacteria

RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing

Synthesis and application of isotopically labeled flavin nucleotides

Acetylation and phosphorylation of mitochondrial transcription factor a promote mitochondrial transcription processivity

Exploring the mechanisms behind the E. coli pH-responsive riboswitch

Conserved Trigger Loop Histidine of RNA Polymerase II Functions as a Positional Catalyst Primarily through Steric Effects

Trigger loop of RNA polymerase is a positional, not acid–base, catalyst for both transcription and proofreading

Mechanisms and inhibition of uracil methylating enzymes

An unprecedented mechanism of nucleotide methylation in organisms containing thyX

Substrate Activation in Flavin-Dependent Thymidylate Synthase

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

Chemical quenching and identification of intermediates in flavoenzyme-catalyzed reactions

Trapping of an Intermediate in the Reaction Catalyzed by Flavin-Dependent Thymidylate Synthase

Structural and mechanistic study of a pH-responsive riboswitch

Conserved mechanisms of transcriptional pausing regulate diverse RNA polymerases

Accurate Measurement of Methyl 13C Chemical Shifts by Solid-State NMR for the Determination of Protein Side Chain Conformation: The Influenza A M2 Transmembrane Peptide as an Example

Accurate Measurement of Methyl 13C Chemical Shifts by Solid-State NMR for the Determination of Protein Sidechain Conformation: the Influenza A M2 Transmembrane Peptide as an Example

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