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From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta

Cardiovascular research, 2018-03, Vol.114 (4), p.578-589

2018

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Asprosin, a Fasting-Induced Glucogenic Protein Hormone

Cell, 2016-04, Vol.165 (3), p.566-579

2016

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Structure of the Elastin-Contractile Units in the Thoracic Aorta and How Genes That Cause Thoracic Aortic Aneurysms and Dissections Disrupt This Structure

Canadian journal of cardiology, 2016-01, Vol.32 (1), p.26-34

2016

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Rescuing the physician-scientist workforce: the time for action is now

The Journal of clinical investigation, 2015-10, Vol.125 (10), p.3742-3747

2015

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Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models

Annual review of medicine, 2017-01, Vol.68 (1), p.51-67

2017

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Altered Smooth Muscle Cell Force Generation as a Driver of Thoracic Aortic Aneurysms and Dissections

Arteriosclerosis, thrombosis, and vascular biology, 2017-01, Vol.37 (1), p.26-34

2017

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Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response

Arteriosclerosis, thrombosis, and vascular biology, 2021-01, Vol.41 (1), p.302-316

2021

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Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture

Circulation (New York, N.Y.), 2020-01, Vol.141 (1), p.42-66

2020

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Asprosin is a centrally acting orexigenic hormone

Nature medicine, 2017-12, Vol.23 (12), p.1444-1453

2017

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Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Journal of the American College of Cardiology, 2018-08, Vol.72 (6), p.605-615

2018

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Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections

American journal of human genetics, 2013-08, Vol.93 (2), p.398-404

2013

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Dysfunctional Mechanosensing in Aneurysms

Science (American Association for the Advancement of Science), 2014-05, Vol.344 (6183), p.477-479

2014

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MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections

American journal of human genetics, 2014-12, Vol.95 (6), p.736-743

2014

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International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes

European journal of cardio-thoracic surgery, 2021-09, Vol.60 (3), p.448-476

2021

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Molecular diagnosis in vascular Ehlers-Danlos syndrome predicts pattern of arterial involvement and outcomes

Journal of vascular surgery, 2014-07, Vol.60 (1), p.160-169

2014

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Endovascular thoracic aortic repair in confirmed or suspected genetically triggered thoracic aortic dissection

Journal of vascular surgery, 2018-08, Vol.68 (2), p.364-371

2018

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MicroRNAs, fibrotic remodeling, and aortic aneurysms

The Journal of clinical investigation, 2012-02, Vol.122 (2), p.490-493

Milewicz, Dianna M

2012

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Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development

Arteriosclerosis, thrombosis, and vascular biology, 2020-12, Vol.40 (12), p.e322

2020

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Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

American journal of human genetics, 2016-09, Vol.99 (3), p.762-769

2016

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Risk Factors for Thoracic Aortic Dissection

Genes, 2022-10, Vol.13 (10), p.1814

2022

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MAT2A Mutations Predispose Individuals to Thoracic Aortic Aneurysms

American journal of human genetics, 2015-01, Vol.96 (1), p.170-177

2015

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Genetics of Thoracic and Abdominal Aortic Diseases: Aneurysms, Dissections, and Ruptures

Circulation research, 2019-02, Vol.124 (4), p.588-606

2019

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Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

Scientific reports, 2017-09, Vol.7 (1), p.12351-14, Article 12351

2017

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Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice

Journal of the American Heart Association, 2020-04, Vol.9 (7), p.e014044-e014044

2020

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Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

American journal of human genetics, 2010-11, Vol.87 (5), p.701-707

2010

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From genetics to response to injury: vascular smooth muscle cells in aneurysms and dissections of the ascending aorta

Asprosin, a Fasting-Induced Glucogenic Protein Hormone

Structure of the Elastin-Contractile Units in the Thoracic Aorta and How Genes That Cause Thoracic Aortic Aneurysms and Dissections Disrupt This Structure

Rescuing the physician-scientist workforce: the time for action is now

Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models

Altered Smooth Muscle Cell Force Generation as a Driver of Thoracic Aortic Aneurysms and Dissections

Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response

Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture

Asprosin is a centrally acting orexigenic hormone

Clinical Validity of Genes for Heritable Thoracic Aortic Aneurysm and Dissection

Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections

Dysfunctional Mechanosensing in Aneurysms

MFAP5 Loss-of-Function Mutations Underscore the Involvement of Matrix Alteration in the Pathogenesis of Familial Thoracic Aortic Aneurysms and Dissections

International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes

Molecular diagnosis in vascular Ehlers-Danlos syndrome predicts pattern of arterial involvement and outcomes

Endovascular thoracic aortic repair in confirmed or suspected genetically triggered thoracic aortic dissection

MicroRNAs, fibrotic remodeling, and aortic aneurysms

Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

Risk Factors for Thoracic Aortic Dissection

MAT2A Mutations Predispose Individuals to Thoracic Aortic Aneurysms

Genetics of Thoracic and Abdominal Aortic Diseases: Aneurysms, Dissections, and Ruptures

Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice

Mutations in Myosin Light Chain Kinase Cause Familial Aortic Dissections

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