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Delivering genes with human immunodeficiency virus-derived vehicles: still state-of-the-art after 25 years

Journal of biomedical science, 2022-10, Vol.29 (1), p.1-79, Article 79

2022

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Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering

Circulation research, 2014-05, Vol.114 (11), p.1684-1689

2014

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Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Hepatology (Baltimore, Md.), 2016-09, Vol.64 (3), p.746-759

2016

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Targeted Knockout of the Vegfa Gene in the Retina by Subretinal Injection of RNP Complexes Containing Cas9 Protein and Modified sgRNAs

Molecular therapy, 2021-01, Vol.29 (1), p.191-207

2021

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Prime editing in hematopoietic stem cells-From ex vivo to in vivo CRISPR-based treatment of blood disorders

Frontiers in genome editing, 2023-03, Vol.5, p.1148650-1148650

2023

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Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema

The Journal of clinical investigation, 2019-01, Vol.129 (1), p.388-405

2019

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Sustained transgene expression from sleeping beauty DNA transposons containing a core fragment of the HNRPA2B1-CBX3 ubiquitous chromatin opening element (UCOE)

BMC biotechnology, 2019-11, Vol.19 (1), p.75-75, Article 75

2019

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DNA transposon-based gene vehicles - scenes from an evolutionary drive

Journal of biomedical science, 2013-12, Vol.20 (1), p.92-92, Article 92

2013

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Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

Arthritis research & therapy, 2015-06, Vol.17 (1), p.154-154, Article 154

2015

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Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

Molecular therapy. Nucleic acids, 2019-06, Vol.16, p.38-50

2019

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In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells

Molecular therapy. Nucleic acids, 2017-12, Vol.9 (C), p.89-99

2017

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Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma

Molecular oncology, 2020-09, Vol.14 (9), p.1978-1997

2020

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CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch

Molecular therapy. Nucleic acids, 2022-09, Vol.29, p.563-576

2022

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piggyPrime: High-Efficacy Prime Editing in Human Cells Using piggyBac-Based DNA Transposition

Frontiers in genome editing, 2021-11, Vol.3, p.786893-786893

2021

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Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression

Frontiers in cellular and infection microbiology, 2022-01, Vol.11, p.784762-784762

2022

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Time-Restricted PiggyBac DNA Transposition by Transposase Protein Delivery Using Lentivirus-Derived Nanoparticles

Molecular therapy. Nucleic acids, 2018-06, Vol.11 (C), p.253-262

2018

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Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein

Molecular therapy. Nucleic acids, 2018-09, Vol.12, p.672-683

2018

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Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin

PloS one, 2012-05, Vol.7 (5), p.e36658-e36658

2012

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Postintegrative Gene Silencing within the Sleeping Beauty Transposition System

Molecular and Cellular Biology, 2007-12, Vol.27 (24), p.8824-8833

2007

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The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells

PloS one, 2012-10, Vol.7 (10), p.e48421-e48421

2012

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Mutational Analysis of the N-Terminal DNA-Binding Domain of Sleeping Beauty Transposase: Critical Residues for DNA Binding and Hyperactivity in Mammalian Cells

Molecular and Cellular Biology, 2004-10, Vol.24 (20), p.9239-9247

2004

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Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

Nature biotechnology, 2002-10, Vol.20 (10), p.999-1005

2002

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Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs

Molecular therapy. Nucleic acids, 2018-12, Vol.13, p.365-375

2018

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Viral delivery of genome-modifying proteins for cellular reprogramming

Current opinion in genetics & development, 2018-10, Vol.52, p.92-99

Mikkelsen, Jacob Giehm

2018

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Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA

The journal of gene medicine, 2012-11, Vol.14 (11), p.632-641

2012

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Delivering genes with human immunodeficiency virus-derived vehicles: still state-of-the-art after 25 years

Induction of Atherosclerosis in Mice and Hamsters Without Germline Genetic Engineering

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection

Targeted Knockout of the Vegfa Gene in the Retina by Subretinal Injection of RNP Complexes Containing Cas9 Protein and Modified sgRNAs

Prime editing in hematopoietic stem cells-From ex vivo to in vivo CRISPR-based treatment of blood disorders

Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema

Sustained transgene expression from sleeping beauty DNA transposons containing a core fragment of the HNRPA2B1-CBX3 ubiquitous chromatin opening element (UCOE)

DNA transposon-based gene vehicles - scenes from an evolutionary drive

Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells

Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma

CRISPR-Cas9-directed gene tagging using a single integrase-defective lentiviral vector carrying a transposase-based Cas9 off switch

piggyPrime: High-Efficacy Prime Editing in Human Cells Using piggyBac-Based DNA Transposition

Single-Cell Monitoring of Activated Innate Immune Signaling by a d2eGFP-Based Reporter Mimicking Time-Restricted Activation of IFNB1 Expression

Time-Restricted PiggyBac DNA Transposition by Transposase Protein Delivery Using Lentivirus-Derived Nanoparticles

Improved Lentiviral Gene Delivery to Mouse Liver by Hydrodynamic Vector Injection through Tail Vein

Development of transgenic cloned pig models of skin inflammation by DNA transposon-directed ectopic expression of human β1 and α2 integrin

Postintegrative Gene Silencing within the Sleeping Beauty Transposition System

The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells

Mutational Analysis of the N-Terminal DNA-Binding Domain of Sleeping Beauty Transposase: Critical Residues for DNA Binding and Hyperactivity in Mammalian Cells

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

Enhanced Tailored MicroRNA Sponge Activity of RNA Pol II-Transcribed TuD Hairpins Relative to Ectopically Expressed ciRS7-Derived circRNAs

Viral delivery of genome-modifying proteins for cellular reprogramming

Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA

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