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Sensing herpes: more than toll

Reviews in medical virology, 2012-03, Vol.22 (2), p.106-121

Melchjorsen, Jesper

2012

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Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines

Viruses, 2013-01, Vol.5 (2), p.470-527

Melchjorsen, Jesper

2013

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Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

The Journal of immunology (1950), 2013-03, Vol.190 (5), p.2311-2319

2013

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Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF-κB than Type I IFNs

Journal of Virology, 2010-05, Vol.84 (9), p.4579-4586

2010

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Early Innate Recognition of Herpes Simplex Virus in Human Primary Macrophages Is Mediated via the MDA5/MAVS-Dependent and MDA5/MAVS/RNA Polymerase III-Independent Pathways

Journal of Virology, 2010-11, Vol.84 (21), p.11350-11358

2010

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Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

PloS one, 2012-01, Vol.7 (1), p.e29291-e29291

2012

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Innate immune recognition and activation during HIV infection

Retrovirology, 2010-06, Vol.7 (1), p.54-54, Article 54

2010

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Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients

PloS one, 2013-04, Vol.8 (4), p.e62074-e62074

2013

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Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner

Journal of Virology, 2005-10, Vol.79 (20), p.12944-12951

2005

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T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication

PloS one, 2014-01, Vol.9 (1), p.e84513-e84513

2014

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Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function

Journal of leukocyte biology, 2003-09, Vol.74 (3), p.331-343

2003

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Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals

PloS one, 2011-06, Vol.6 (6), p.e21275-e21275

2011

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Cytosolic RNA Recognition Pathway Activates 14-3-3 Protein Mediated Signaling and Caspase-Dependent Disruption of Cytokeratin Network in Human Keratinocytes

Journal of proteome research, 2010-03, Vol.9 (3), p.1549-1564

2010

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Activation and evasion of innate antiviral immunity by herpes simplex virus

Viruses, 2009-12, Vol.1 (3), p.737-759

2009

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Timing of Toll-Like Receptor 9 Agonist Administration in Pneumococcal Vaccination Impacts Both Humoral and Cellular Immune Responses as Well as Nasopharyngeal Colonization in Mice

Infection and Immunity, 2012-05, Vol.80 (5), p.1744-1752

2012

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Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy

BMC infectious diseases, 2011-10, Vol.11 (1), p.267-267, Article 267

2011

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Characterization of HIV-1 Infection and Innate Sensing in Different Types of Primary Human Monocyte-Derived Macrophages

Mediators of Inflammation, 2013-01, Vol.2013, p.208412-11

2013

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Suppression of Proinflammatory Cytokine Expression by Herpes Simplex Virus Type 1

Journal of Virology, 2004-06, Vol.78 (11), p.5883-5890

2004

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TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults

Human vaccines & immunotherapeutics, 2012-08, Vol.8 (8), p.1042-1047

2012

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Herpes Simplex Virus Selectively Induces Expression of the CC Chemokine RANTES/CCL5 in Macrophages through a Mechanism Dependent on PKR and ICP0

Journal of Virology, 2002-03, Vol.76 (6), p.2780-2788

2002

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RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells

The Journal of biological chemistry, 2009-04, Vol.284 (16), p.10774-10782

2009

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Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

Virology journal, 2011-08, Vol.8 (1), p.381-381, Article 381

2011

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Comparison of HDAC inhibitors in clinical development: Effect on HIV production in latently infected cells and T-cell activation

Human vaccines & immunotherapeutics, 2013-05, Vol.9 (5), p.993-1001

2013

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Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-κB and IRF-3

Journal of general virology, 2006-05, Vol.87 (5), p.1099-1108

2006

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RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells: DEPENDENCE ON TRAF2 AND TAK1

The Journal of biological chemistry, 2009-04, Vol.284 (16), p.10774-10782

2009

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Sensing herpes: more than toll

Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines

Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

Expression of Type III Interferon (IFN) in the Vaginal Mucosa Is Mediated Primarily by Dendritic Cells and Displays Stronger Dependence on NF-κB than Type I IFNs

Early Innate Recognition of Herpes Simplex Virus in Human Primary Macrophages Is Mediated via the MDA5/MAVS-Dependent and MDA5/MAVS/RNA Polymerase III-Independent Pathways

Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

Innate immune recognition and activation during HIV infection

Administration of a Toll-like receptor 9 agonist decreases the proviral reservoir in virologically suppressed HIV-infected patients

Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner

T cells detect intracellular DNA but fail to induce type I IFN responses: implications for restriction of HIV replication

Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function

Endotoxemia is associated with altered innate and adaptive immune responses in untreated HIV-1 infected individuals

Cytosolic RNA Recognition Pathway Activates 14-3-3 Protein Mediated Signaling and Caspase-Dependent Disruption of Cytokeratin Network in Human Keratinocytes

Activation and evasion of innate antiviral immunity by herpes simplex virus

Timing of Toll-Like Receptor 9 Agonist Administration in Pneumococcal Vaccination Impacts Both Humoral and Cellular Immune Responses as Well as Nasopharyngeal Colonization in Mice

Evaluation of cardiovascular biomarkers in HIV-infected patients switching to abacavir or tenofovir based therapy

Characterization of HIV-1 Infection and Innate Sensing in Different Types of Primary Human Monocyte-Derived Macrophages

Suppression of Proinflammatory Cytokine Expression by Herpes Simplex Virus Type 1

TLR9-adjuvanted pneumococcal conjugate vaccine induces antibody-independent memory responses in HIV-infected adults

Herpes Simplex Virus Selectively Induces Expression of the CC Chemokine RANTES/CCL5 in Macrophages through a Mechanism Dependent on PKR and ICP0

RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells

Induction of humoral and cellular immune responses against the HIV-1 envelope protein using γ-retroviral virus-like particles

Comparison of HDAC inhibitors in clinical development: Effect on HIV production in latently infected cells and T-cell activation

Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-κB and IRF-3

RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells: DEPENDENCE ON TRAF2 AND TAK1

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