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Clinical Drug–Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib

Clinical pharmacology in drug development, 2017-05, Vol.6 (3), p.280-291

2017

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Effect of the Wetting Agent Sodium Lauryl Sulfate on the Pharmacokinetics of Alectinib: Results From a Bioequivalence Study in Healthy Subjects

Clinical pharmacology in drug development, 2017-05, Vol.6 (3), p.266-279

2017

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Evaluation of the Effects of Bitopertin (RG1678) on Cardiac Repolarization: A Thorough Corrected QT Study in Healthy Male Volunteers

Clinical therapeutics, 2012-10, Vol.34 (10), p.2061-2071

2012

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CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials

Nature communications, 2024-05, Vol.15 (1), p.4091-14, Article 4091

2024

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Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure

Frontiers in immunology, 2024-05, Vol.15, p.1406353-1406353

2024

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Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example

Clinical pharmacokinetics, 2016-07, Vol.55 (7), p.823-832

2016

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Dose‐dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

British journal of clinical pharmacology, 2002-06, Vol.53 (6), p.576-581

2002

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Drug Dosage in Patients with Renal Failure Optimized by Immediate Concurrent Feedback

Journal of general internal medicine : JGIM, 2001-06, Vol.16 (6), p.369-375

2001

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Undeclared exposure to St. John's Wort in hospitalized patients

British journal of clinical pharmacology, 2004-10, Vol.58 (4), p.437-441

2004

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Inhibition of P-glycoprotein by newer antidepressants

The Journal of pharmacology and experimental therapeutics, 2003-04, Vol.305 (1), p.197-204

2003

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Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects

Clinical pharmacology in drug development, 2017-07, Vol.6 (4), p.388-397

2017

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Poster #226 SAFETY, TOLERABILITY AND PHARMACOKINETICS OF RG1678, A NOVEL GLYCINE REUPTAKE INHIBITOR, AFTER MULTIPLE DOSES IN HEALTHY VOLUNTEERS

Schizophrenia research, 2012-04, Vol.136, p.S267-S267

2012

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Quality of drug information on the World Wide Web and strategies to improve pages with poor information quality. An intervention study on pages about sildenafil

British journal of clinical pharmacology, 2004-01, Vol.57 (1), p.80-85

2004

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Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study

JAMA psychiatry (Chicago, Ill.), 2014-06, Vol.71 (6), p.637

2014

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Oral Contraception Does Not Alter Single Dose Saquinavir Pharmacokinetics in Women

British journal of clinical pharmacology, 2004-03, Vol.57 (3), p.244-252

2004

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Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-12, Vol.813 (1), p.27-33

2004

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Physiologically Based Absorption Modelling to Predict the Impact of Drug Properties on Pharmacokinetics of Bitopertin

The AAPS journal, 2014-09, Vol.16 (5), p.1077-1084

2014

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Human activity recognition from sensor-based large-scale continuous monitoring of Parkinson's disease patients

2017 IEEE/ACM International Conference on Connected Health: Applications, Systems and Engineering Technologies (CHASE), 2017, p.249-250

2017

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Highly sensitive determination of saquinavir in biological samples using liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-02, Vol.784 (2), p.233-242

2003

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Unexplained decrease of cyclosporin trough levels in a compliant renal transplant patient

Nephrology, dialysis, transplantation, 2000-09, Vol.15 (9), p.1473-1474

2000

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Managing the Impact of Immunogenicity in an Era of Immunotherapy: From Bench to Bedside

Journal of pharmaceutical sciences, 2021-07, Vol.110 (7), p.2575-2584

2021

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Absorption, distribution, metabolism and excretion (ADME) of the ALK inhibitor alectinib: results from an absolute bioavailability and mass balance study in healthy subjects

Xenobiotica, 2017-03, Vol.47 (3), p.217-229

2017

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Arzneimittel-Interaktionen am Cytochrom-P450-System

Deutsche medizinische Wochenschrift, 2008-03, Vol.125 (3), p.63-67

2008

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Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers

Psychopharmacology, 2016-07, Vol.233 (13), p.2429-2439

2016

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Effects of Cytochrome P450 3A4 Inhibitors—Ketoconazole and Erythromycin—on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions

Clinical pharmacokinetics, 2016-02, Vol.55 (2), p.237-247

2016

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Clinical Drug–Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib

Effect of the Wetting Agent Sodium Lauryl Sulfate on the Pharmacokinetics of Alectinib: Results From a Bioequivalence Study in Healthy Subjects

Evaluation of the Effects of Bitopertin (RG1678) on Cardiac Repolarization: A Thorough Corrected QT Study in Healthy Male Volunteers

CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials

Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure

Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example

Dose‐dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

Drug Dosage in Patients with Renal Failure Optimized by Immediate Concurrent Feedback

Undeclared exposure to St. John's Wort in hospitalized patients

Inhibition of P-glycoprotein by newer antidepressants

Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects

Poster #226 SAFETY, TOLERABILITY AND PHARMACOKINETICS OF RG1678, A NOVEL GLYCINE REUPTAKE INHIBITOR, AFTER MULTIPLE DOSES IN HEALTHY VOLUNTEERS

Quality of drug information on the World Wide Web and strategies to improve pages with poor information quality. An intervention study on pages about sildenafil

Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study

Oral Contraception Does Not Alter Single Dose Saquinavir Pharmacokinetics in Women

Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography–tandem mass spectrometry

Physiologically Based Absorption Modelling to Predict the Impact of Drug Properties on Pharmacokinetics of Bitopertin

Human activity recognition from sensor-based large-scale continuous monitoring of Parkinson's disease patients

Highly sensitive determination of saquinavir in biological samples using liquid chromatography–tandem mass spectrometry

Unexplained decrease of cyclosporin trough levels in a compliant renal transplant patient

Managing the Impact of Immunogenicity in an Era of Immunotherapy: From Bench to Bedside

Absorption, distribution, metabolism and excretion (ADME) of the ALK inhibitor alectinib: results from an absolute bioavailability and mass balance study in healthy subjects

Arzneimittel-Interaktionen am Cytochrom-P450-System

Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers

Effects of Cytochrome P450 3A4 Inhibitors—Ketoconazole and Erythromycin—on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions

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