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A highly conserved δ‐opioid receptor region determines RGS4 interaction

The FEBS journal, 2020-02, Vol.287 (4), p.736-748

2020

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Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.629

2021

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Comprehensive identification of RNA-protein interactions in any organism using orthogonal organic phase separation (OOPS)

Nature biotechnology, 2019-02, Vol.37 (2), p.169-178

2019

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Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable

Neuron (Cambridge, Mass.), 2020-12, Vol.108 (6), p.1146-1162.e10

2020

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Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design

Current pharmaceutical design, 2013, Vol.19 (28), p.5156-5166

2013

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Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry

Drug discovery today, 2016-04, Vol.21 (4), p.625-631

2016

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Application of BRET for studying G protein-coupled receptors

Mini reviews in medicinal chemistry, 2014-05, Vol.14 (5), p.411-425

2014

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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

Nature communications, 2019-02, Vol.10 (1), p.667-12, Article 667

2019

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Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

Cell reports (Cambridge), 2021-03, Vol.34 (12), p.108862-108862, Article 108862

2021

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Membrane cholesterol access into a G-protein-coupled receptor

Nature communications, 2017-02, Vol.8 (1), p.14505-14505, Article 14505

2017

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Detection of new biased agonists for the serotonin 5-HT2A receptor: modeling and experimental validation

Molecular pharmacology, 2015-04, Vol.87 (4), p.740-746

2015

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Inversions and adaptation to the plant toxin ouabain shape DNA sequence variation within and between chromosomal inversions of Drosophila subobscura

Scientific reports, 2016-03, Vol.6 (1), p.23754, Article 23754

2016

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A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity

PloS one, 2014-10, Vol.9 (10), p.e109312

2014

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Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness

Scientific reports, 2016-06, Vol.6 (1), p.27546-27546, Article 27546

2016

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Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles

European journal of medicinal chemistry, 2014-04, Vol.77, p.91-95

2014

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A multi-dimensional view of context-dependent G protein-coupled receptor function

Biochemical Society transactions, 2023-02, Vol.51 (1), p.13-20

Marti-Solano, Maria

2023

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Mechanisms of signalling and biased agonism in G protein-coupled receptors

Nature reviews. Molecular cell biology, 2018-10, Vol.19 (10), p.638-653

2018

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Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization

European journal of pharmacology, 2017-11, Vol.815, p.138-146

2017

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Combinatorial expression of GPCR isoforms affects signalling and drug responses

Nature (London), 2020-11, Vol.587 (7835), p.650-656

2020

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Molecular determinants of ligand efficacy and potency in GPCR signaling

Science (American Association for the Advancement of Science), 2023-12, Vol.382 (6677), p.eadh1859-eadh1859

2023

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The allosteric site regulates the voltage sensitivity of muscarinic receptors

Cellular signalling, 2018-01, Vol.42, p.114-126

2018

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Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses

Nature (London), 2020-12, Vol.588 (7838), p.E24-E24

2020

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POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer

Oncotarget, 2017-04, Vol.8 (16), p.26732-26743

2017

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Integrative knowledge management to enhance pharmaceutical R&D

Nature reviews. Drug discovery, 2014-04, Vol.13 (4), p.239-240

2014

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Author Correction: Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)

Nature biotechnology, 2019-06, Vol.37 (6), p.692-692

2019

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A highly conserved δ‐opioid receptor region determines RGS4 interaction

Analyzing Kinase Similarity in Small Molecule and Protein Structural Space to Explore the Limits of Multi-Target Screening

Comprehensive identification of RNA-protein interactions in any organism using orthogonal organic phase separation (OOPS)

Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable

Novel insights into biased agonism at G protein-coupled receptors and their potential for drug design

Drugging specific conformational states of GPCRs: challenges and opportunities for computational chemistry

Application of BRET for studying G protein-coupled receptors

A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

Membrane cholesterol access into a G-protein-coupled receptor

Detection of new biased agonists for the serotonin 5-HT2A receptor: modeling and experimental validation

Inversions and adaptation to the plant toxin ouabain shape DNA sequence variation within and between chromosomal inversions of Drosophila subobscura

A dynamic view of molecular switch behavior at serotonin receptors: implications for functional selectivity

Codon optimization of the adenoviral fiber negatively impacts structural protein expression and viral fitness

Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profiles

A multi-dimensional view of context-dependent G protein-coupled receptor function

Mechanisms of signalling and biased agonism in G protein-coupled receptors

Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization

Combinatorial expression of GPCR isoforms affects signalling and drug responses

Molecular determinants of ligand efficacy and potency in GPCR signaling

The allosteric site regulates the voltage sensitivity of muscarinic receptors

Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses

POLE and POLD1 screening in 155 patients with multiple polyps and early-onset colorectal cancer

Integrative knowledge management to enhance pharmaceutical R&D

Author Correction: Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS)

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