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Spatially controlled hydrogel mechanics to modulate stem cell interactions

Soft matter, 2010-01, Vol.6 (1), p.136-143

2010

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Functionally-Relevant Morphological Profiling: A Tool to Assess Cellular Heterogeneity

Trends in biotechnology (Regular ed.), 2018-01, Vol.36 (1), p.105-118

2018

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The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers

Biomaterials, 2008-05, Vol.29 (15), p.2348-2358

2008

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High Content Imaging of Early Morphological Signatures Predicts Long Term Mineralization Capacity of Human Mesenchymal Stem Cells upon Osteogenic Induction

Stem cells (Dayton, Ohio), 2016-04, Vol.34 (4), p.935-947

2016

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Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness

Clinical autonomic research, 2022-02, Vol.32 (1), p.59-63

2022

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Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules

Biomaterials, 2009-05, Vol.30 (13), p.2507-2515

2009

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Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity

Stem cells translational medicine, 2018-09, Vol.7 (9), p.664-675

2018

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High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

Bioactive materials, 2024-07, Vol.37, p.153-171

2024

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Controlling Stem Cell Fate with Material Design

Advanced materials (Weinheim), 2010-01, Vol.22 (2), p.175-189

2010

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Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (13), p.E2598-E2607

2017

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Morphological landscapes from high content imaging reveal cytokine priming strategies that enhance mesenchymal stromal cell immunosuppression

Biotechnology and bioengineering, 2022-02, Vol.119 (2), p.361-375

2022

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Morphological profiling using machine learning reveals emergent subpopulations of interferon-γ–stimulated mesenchymal stromal cells that predict immunosuppression

Cytotherapy (Oxford, England), 2019-01, Vol.21 (1), p.17-31

2019

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Development of a Robust Consensus Modeling Approach for Identifying Cellular and Media Metabolites Predictive of Mesenchymal Stromal Cell Potency

Stem cells (Dayton, Ohio), 2023-08, Vol.41 (8), p.792-808

2023

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Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression

Cytotherapy (Oxford, England), 2022-02, Vol.24 (2), p.137-148

2022

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Identification of Predictive Gene Markers for Multipotent Stromal Cell Proliferation

Stem cells and development, 2016-06, Vol.25 (11), p.861-873

2016

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Adaptation of a Simple Microfluidic Platform for High-Dimensional Quantitative Morphological Analysis of Human Mesenchymal Stromal Cells on Polystyrene-Based Substrates

SLAS technology, 2017-12, Vol.22 (6), p.646-661

2017

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Photocleavable side groups to spatially alter hydrogel properties and cellular interactions

Journal of materials chemistry, 2010-10, Vol.2 (4), p.892-8926

2010

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Morphological landscapes from high content imaging reveal cytokine priming strategies that enhance mesenchymal stromal cell immunosuppression

Biotechnology and bioengineering, 2021-11, Vol.119 (2)

2021

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Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels

Soft matter, 2012-01, Vol.8 (31), p.8113

2012

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Morphological features of IFN-[gamma]-stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (13), p.E2598

2017

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Shape up before you ship out: morphology as a potential critical quality attribute for cellular therapies

Current opinion in biomedical engineering, 2021-12, Vol.20, p.100352, Article 100352

2021

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Engineering the 3D microenvironment of embryonic stem cells undergoing differentiation

Bio-medical materials and engineering, 2008, Vol.18 (4-5), p.179-181

2008

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Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogelsElectronic Supplementary Information (ESI) available: values for secretory profile raw data. See DOI: 10.1039/c2sm25501d

2012-07

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Spatially and temporally controlled mechanical signals to direct human mesenchymal stem cell behavior

Marklein, Ross A

2012

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Biomanufacturing of Mesenchymal Stromal Cells for Therapeutic Applications

Cell Culture Engineering and Technology, p.267-306

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Spatially controlled hydrogel mechanics to modulate stem cell interactions

Functionally-Relevant Morphological Profiling: A Tool to Assess Cellular Heterogeneity

The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers

High Content Imaging of Early Morphological Signatures Predicts Long Term Mineralization Capacity of Human Mesenchymal Stem Cells upon Osteogenic Induction

Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness

Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules

Functional Profiling of Chondrogenically Induced Multipotent Stromal Cell Aggregates Reveals Transcriptomic and Emergent Morphological Phenotypes Predictive of Differentiation Capacity

High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

Controlling Stem Cell Fate with Material Design

Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

Morphological landscapes from high content imaging reveal cytokine priming strategies that enhance mesenchymal stromal cell immunosuppression

Morphological profiling using machine learning reveals emergent subpopulations of interferon-γ–stimulated mesenchymal stromal cells that predict immunosuppression

Development of a Robust Consensus Modeling Approach for Identifying Cellular and Media Metabolites Predictive of Mesenchymal Stromal Cell Potency

Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression

Identification of Predictive Gene Markers for Multipotent Stromal Cell Proliferation

Adaptation of a Simple Microfluidic Platform for High-Dimensional Quantitative Morphological Analysis of Human Mesenchymal Stromal Cells on Polystyrene-Based Substrates

Photocleavable side groups to spatially alter hydrogel properties and cellular interactions

Morphological landscapes from high content imaging reveal cytokine priming strategies that enhance mesenchymal stromal cell immunosuppression

Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels

Morphological features of IFN-[gamma]-stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

Shape up before you ship out: morphology as a potential critical quality attribute for cellular therapies

Engineering the 3D microenvironment of embryonic stem cells undergoing differentiation

Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogelsElectronic Supplementary Information (ESI) available: values for secretory profile raw data. See DOI: 10.1039/c2sm25501d

Spatially and temporally controlled mechanical signals to direct human mesenchymal stem cell behavior

Biomanufacturing of Mesenchymal Stromal Cells for Therapeutic Applications

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