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Self-assembling protein nanoparticles in the design of vaccines

Computational and structural biotechnology journal, 2016-01, Vol.14 (C), p.58-68

2016

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Protein Crystallography in Vaccine Research and Development

International Journal of Molecular Sciences, 2015-06, Vol.16 (6), p.13106-13140

2015

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Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5229-5234

2012

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Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

Journal of Immunology Research, 2015-01, Vol.2015, p.156241-17

2015

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Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6183

2023

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Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (9), p.3304-3309

2013

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Crystal Structure of a Baeyer-Villiger Monooxygenase

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (36), p.13157-13162

2004

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Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein

mAbs, 2021-01, Vol.13 (1), p.1955812-1955812

2021

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Structural basis for potent antibody-mediated neutralization of human cytomegalovirus

Science immunology, 2017-06, Vol.2 (12)

2017

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Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.17128-17133

2014

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Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F

PLoS pathogens, 2020-11, Vol.16 (11), p.e1008943-e1008943

2020

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Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

PloS one, 2018-08, Vol.13 (8), p.e0201922-e0201922

2018

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Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

PLoS pathogens, 2016-04, Vol.12 (4), p.e1005557

2016

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NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies

mBio, 2018-10, Vol.9 (5)

2018

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Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

The Journal of biological chemistry, 2009-05, Vol.284 (21), p.14177-14188

2009

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Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius

Bioscience reports, 2014-11, Vol.34 (6), p.e00154

2014

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Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis

The Journal of biological chemistry, 2009-05, Vol.284 (21), p.14645-14656

2009

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Structure and assembly of group B streptococcus pilus 2b backbone protein

PloS one, 2015-05, Vol.10 (5), p.e0125875

2015

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Structure of Substrate-free Human Insulin-degrading Enzyme (IDE) and Biophysical Analysis of ATP-induced Conformational Switch of IDE

The Journal of biological chemistry, 2007-08, Vol.282 (35), p.25453-25463

2007

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Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

PloS one, 2010-05, Vol.5 (5), p.e10504

2010

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Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096

Computational and structural biotechnology journal, 2022-01, Vol.20, p.2070-2081

2022

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Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes

Computational and structural biotechnology journal, 2020-01, Vol.18, p.650-660

2020

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Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus

PloS one, 2010-06, Vol.5 (6), p.e10919-e10919

2010

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Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus

Biochemical journal, 2013-11, Vol.455 (3), p.273-284

2013

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Modular Total Chemical Synthesis of a Human Immunodeficiency Virus Type 1 Protease

Journal of the American Chemical Society, 2007-09, Vol.129 (37), p.11480-11490

2007

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Self-assembling protein nanoparticles in the design of vaccines

Protein Crystallography in Vaccine Research and Development

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197

Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

Crystal Structure of a Baeyer-Villiger Monooxygenase

Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein

Structural basis for potent antibody-mediated neutralization of human cytomegalovirus

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F

Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody

Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies

Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius

Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis

Structure and assembly of group B streptococcus pilus 2b backbone protein

Structure of Substrate-free Human Insulin-degrading Enzyme (IDE) and Biophysical Analysis of ATP-induced Conformational Switch of IDE

Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin

Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096

Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes

Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus

Modular Total Chemical Synthesis of a Human Immunodeficiency Virus Type 1 Protease

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