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Physicochemical considerations in the formulation development of silicone elastomer vaginal rings releasing 5-nitroimidazole drugs for the treatment of bacterial vaginosis

International journal of pharmaceutics, 2023-09, Vol.644, p.123296-123296, Article 123296

2023

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Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques

Antimicrobial Agents and Chemotherapy, 2012-05, Vol.56 (5), p.2251-2258

2012

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Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations

Journal of controlled release, 2012-09, Vol.162 (3), p.529-537

2012

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First-in-human study to assess the pharmacokinetics, tolerability, and safety of single-dose oxybutynin hydrochloride administered via a microprocessor-controlled intravaginal ring

Drug delivery, 2023-12, Vol.30 (1), p.2180113-2180113

2023

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Dapivirine-releasing vaginal rings produced by plastic freeforming additive manufacturing

International journal of pharmaceutics, 2019-12, Vol.572, p.118725-118725, Article 118725

2019

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Editorial: Multipurpose prevention technologies for HIV, STIs and pregnancies

Frontiers in reproductive health, 2024, Vol.6, p.1384153-1384153

2024

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A temperature-monitoring vaginal ring for measuring adherence

PloS one, 2015-05, Vol.10 (5), p.e0125682

2015

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Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers

Green chemistry : an international journal and green chemistry resource : GC, , Vol.13 (6), p.1527-1535

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Vaginal rings for delivery of HIV microbicides

International journal of women's health, 2012-01, Vol.4 (default), p.595-605

2012

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Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc

Journal of controlled release, 2011-12, Vol.156 (2), p.161-169

2011

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Characterization of the Rheological, Mucoadhesive, and Drug Release Properties of Highly Structured Gel Platforms for Intravaginal Drug Delivery

Biomacromolecules, 2009-09, Vol.10 (9), p.2427-2435

2009

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Modified Silicone Elastomer Vaginal Gels for Sustained Release of Antiretroviral HIV Microbicides

Journal of pharmaceutical sciences, 2014-05, Vol.103 (5), p.1422-1432

2014

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Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel

International journal of pharmaceutics: X, 2021-12, Vol.3, p.100091-100091, Article 100091

2021

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Persistence of antimicrobial activity through sustained release of triclosan from pegylated silicone elastomers

Biomaterials, 2009-12, Vol.30 (35), p.6739-6747

2009

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Development of liposome gel based formulations for intravaginal delivery of the recombinant HIV-1 envelope protein CN54gp140

European journal of pharmaceutical sciences, 2012-08, Vol.46 (5), p.315-322

2012

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In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel

International journal of pharmaceutics: X, 2022-12, Vol.4, p.100112-100112, Article 100112

2022

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Microbicide vaginal rings: Technological challenges and clinical development

Advanced drug delivery reviews, 2016-08, Vol.103, p.33-56

2016

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Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings

International journal of pharmaceutics: X, 2021-12, Vol.3, p.100081-100081, Article 100081

2021

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The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans

iScience, 2022-06, Vol.25 (6), p.104409-104409, Article 104409

2022

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Rheological evaluation of the isothermal cure characteristics of medical grade silicone elastomers

Journal of applied polymer science, 2010-05, Vol.116 (4), p.2320-2327

2010

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Development of polylactide and polyethylene vinyl acetate blends for the manufacture of vaginal rings

Journal of biomedical materials research. Part B, Applied biomaterials, 2012-05, Vol.100B (4), p.891-895

2012

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The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals

Expert opinion on drug delivery, 2020-11, Vol.17 (11), p.1519-1540

2020

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Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

Vaccine, 2011-06, Vol.29 (27), p.4512-4520

2011

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Effect of the incorporation of hydroxy-terminated liquid silicones on the cure characteristics, morphology, and release of a model protein from silicone elastomer-covered rods

Journal of applied polymer science, 2012-04, Vol.124 (1), p.805-812

2012

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Intravaginal rings for continuous low-dose administration of cervical ripening agents

International journal of pharmaceutics, 2018-10, Vol.549 (1-2), p.124-132

2018

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Physicochemical considerations in the formulation development of silicone elastomer vaginal rings releasing 5-nitroimidazole drugs for the treatment of bacterial vaginosis

Sustained Release of the CCR5 Inhibitors CMPD167 and Maraviroc from Vaginal Rings in Rhesus Macaques

Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations

First-in-human study to assess the pharmacokinetics, tolerability, and safety of single-dose oxybutynin hydrochloride administered via a microprocessor-controlled intravaginal ring

Dapivirine-releasing vaginal rings produced by plastic freeforming additive manufacturing

Editorial: Multipurpose prevention technologies for HIV, STIs and pregnancies

A temperature-monitoring vaginal ring for measuring adherence

Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers

Vaginal rings for delivery of HIV microbicides

Non-aqueous silicone elastomer gels as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc

Characterization of the Rheological, Mucoadhesive, and Drug Release Properties of Highly Structured Gel Platforms for Intravaginal Drug Delivery

Modified Silicone Elastomer Vaginal Gels for Sustained Release of Antiretroviral HIV Microbicides

Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel

Persistence of antimicrobial activity through sustained release of triclosan from pegylated silicone elastomers

Development of liposome gel based formulations for intravaginal delivery of the recombinant HIV-1 envelope protein CN54gp140

In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel

Microbicide vaginal rings: Technological challenges and clinical development

Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings

The ex vivo pharmacology of HIV-1 antiretrovirals differs between macaques and humans

Rheological evaluation of the isothermal cure characteristics of medical grade silicone elastomers

Development of polylactide and polyethylene vinyl acetate blends for the manufacture of vaginal rings

The ins and outs of drug-releasing vaginal rings: a literature review of expulsions and removals

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

Effect of the incorporation of hydroxy-terminated liquid silicones on the cure characteristics, morphology, and release of a model protein from silicone elastomer-covered rods

Intravaginal rings for continuous low-dose administration of cervical ripening agents

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