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Signaling mechanisms that regulate smooth muscle cell differentiation

Arteriosclerosis, thrombosis, and vascular biology, 2011-07, Vol.31 (7), p.1495

Mack, Christopher P

2011

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Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

The Journal of biological chemistry, 2017-02, Vol.292 (6), p.2065-2079

2017

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GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis

Nature communications, 2023-12, Vol.14 (1), p.8187-8187, Article 8187

2023

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The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension

Nature communications, 2013-12, Vol.4 (1), p.2910-2910, Article 2910

2013

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Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain

Biochemical journal, 2011-10, Vol.439 (1), p.57-65

2011

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Skeletal Muscle Differentiation and Fusion Are Regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF1

The Journal of biological chemistry, 2011-07, Vol.286 (29), p.25903-25921

2011

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GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes

Cells (Basel, Switzerland), 2024-03, Vol.13 (5), p.448

2024

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A Primer on Repeated Sitting Exposure and the Cardiovascular System: Considerations for Study Design, Analysis, Interpretation, and Translation

Frontiers in cardiovascular medicine, 2021-08, Vol.8, p.716938

2021

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Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors

American journal of physiology. Heart and circulatory physiology, 2007-02, Vol.292 (2), p.H1170-H1180

2007

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Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury

Arteriosclerosis, thrombosis, and vascular biology, 2012-04, Vol.32 (4), p.924

2012

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Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation

Arteriosclerosis, thrombosis, and vascular biology, 2010-09, Vol.30 (9), p.1779

2010

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Sphingosine 1-Phosphate Stimulates Smooth Muscle Cell Differentiation and Proliferation by Activating Separate Serum Response Factor Co-factors

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42422-42430

2004

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Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility

JCI insight, 2023-03, Vol.8 (5)

2023

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Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload–Induced Hypertrophy

Circulation research, 2006-09, Vol.99 (6), p.636-645

2006

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Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype

Arteriosclerosis, thrombosis, and vascular biology, 2011-02, Vol.31 (2), p.360

2011

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RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

Nucleic acids research, 2018-09, Vol.46 (16), p.8232

2018

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Transient Expression of FRNK Reveals Stage-Specific Requirement for Focal Adhesion Kinase Activity in Cardiac Growth

Circulation research, 2009-05, Vol.104 (10), p.1201-1208

2009

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The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation

American journal of physiology. Heart and circulatory physiology, 2021-11, Vol.321 (5), p.H893-H904

2021

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Focal adhesion kinase is essential for cardiac looping and multichamber heart formation

Genesis (New York, N.Y. : 2000), 2010-08, Vol.48 (8), p.492-504

2010

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FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury

Arteriosclerosis, thrombosis, and vascular biology, 2008-12, Vol.28 (12), p.2115

2008

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Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment

Molecular and Cellular Biology, 2007-08, Vol.27 (15), p.5352-5364

2007

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Druggable targets in the Rho pathway and their promise for therapeutic control of blood pressure

Pharmacology & therapeutics (Oxford), 2019-01, Vol.193, p.121-134

2019

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Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature

Arteriosclerosis, thrombosis, and vascular biology, 2011-10, Vol.31 (10), p.2193

2011

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Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype

Arteriosclerosis, thrombosis, and vascular biology, 2015-11, Vol.35 (11), p.2374

2015

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The Histone Demethylase, Jmjd1a, Interacts With the Myocardin Factors to Regulate SMC Differentiation Marker Gene Expression

Circulation research, 2007-12, Vol.101 (12), p.e115-e123

2007

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Signaling mechanisms that regulate smooth muscle cell differentiation

Focal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth

GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis

The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension

Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain

Skeletal Muscle Differentiation and Fusion Are Regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF1

GRAF1 Acts as a Downstream Mediator of Parkin to Regulate Mitophagy in Cardiomyocytes

A Primer on Repeated Sitting Exposure and the Cardiovascular System: Considerations for Study Design, Analysis, Interpretation, and Translation

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors

Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury

Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation

Sphingosine 1-Phosphate Stimulates Smooth Muscle Cell Differentiation and Proliferation by Activating Separate Serum Response Factor Co-factors

Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility

Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload–Induced Hypertrophy

Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype

RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

Transient Expression of FRNK Reveals Stage-Specific Requirement for Focal Adhesion Kinase Activity in Cardiac Growth

The actin depolymerizing factor destrin serves as a negative feedback inhibitor of smooth muscle cell differentiation

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation

FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury

Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment

Druggable targets in the Rho pathway and their promise for therapeutic control of blood pressure

Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature

Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype

The Histone Demethylase, Jmjd1a, Interacts With the Myocardin Factors to Regulate SMC Differentiation Marker Gene Expression

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