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Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

Nature (London), 2014-12, Vol.516 (7529), p.126-130

2014

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X-ray structure of the mammalian GIRK2-βγ G-protein complex

Nature (London), 2013-06, Vol.498 (7453), p.190-197

2013

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Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Science (American Association for the Advancement of Science), 2009-12, Vol.326 (5960), p.1668-1674

2009

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Cryo-electron microscopy structure of the Slo2.2 Na+-activated K+ channel

Nature (London), 2015-11, Vol.527 (7577), p.198-203

2015

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Molecular structures of the human Slo1 K + channel in complex with β4

eLife, 2019-12, Vol.8

2019

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Molecular structure of an open human KATP channel

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (48)

2021

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Chemistry of ion coordination and hydration revealed by a K + channel-Fab complex at 2.0 resolution

Nature (London), 2001-11, Vol.414 (6859), p.43-48

2001

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Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels

eLife, 2016-04, Vol.5

2016

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The mechanism of Gαq regulation of PLCβ-catalyzed PIP2 hydrolysis

Biophysical journal, 2024-02, Vol.123 (3), p.451a-451a

2024

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Ligand-Dependent Structural States of a K+Channel Analyzed by Cryo-EM

Biophysical journal, 2017-02, Vol.112 (3), p.14a-14a

MacKinnon, Roderick

2017

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The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (21), p.e2301985120

2023

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Determining native-like membrane protein structures from cell membrane-derived vesicles

Biophysical journal, 2024-02, Vol.123 (3), p.299a-299a

2024

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Structural Basis of Inward Rectification: Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 Å Resolution

Cell, 2002-12, Vol.111 (7), p.957-965

2002

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The mechanism of Gα q regulation of PLCβ3 -catalyzed PIP2 hydrolysis

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (48), p.e2315011120

2023

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Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surface

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (20), p.e2301121120-e2301121120

2023

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Structure of the Human BK Channel Ca²⁺-Activation Apparatus at 3.0 Å Resolution

Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5988), p.182-186

2010

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Structural basis for gating the highconductance Ca^sup 2+^-activated K^sup +^ channel

Nature (London), 2017-01, Vol.541 (7635), p.52

2017

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Cryo-EM structure of the open highconductance Ca^sup 2+^-activated K^sup +^ channel

Nature (London), 2017-01, Vol.541 (7635), p.46

2017

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The Structural Basis of Voltage Sensing

Biophysical journal, 2010-01, Vol.98 (3), p.754a-754a

MacKinnon, Roderick

2010

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Purification and Characterization of Three Inhibitors of Voltage-Dependent K+ Channels from Leiurus Quinquestriatus var. Hebraeus Venom

Biochemistry (Easton), 1994-06, Vol.33 (22), p.6834-6839

1994

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Structural Response of the Piezo Channel to Force Application at Different Frequencies

Biophysical journal, 2021-02, Vol.120 (3), p.234a-234a

2021

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X-ray structure of the mammalian GIRK2-[beta][gamma] G-protein complex

Nature (London), 2013-06, Vol.498 (7453), p.190

2013

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X-ray structure of a CIC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Nature (London), 2002-01, Vol.415 (6869), p.287-294

2002

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Structural Response of the Piezo Channel Upon Application of Force

Biophysical journal, 2019-02, Vol.116 (3), p.301a-301a

2019

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Structure of the voltage-gated K⁺ channel Eagl reveals an alternative voltage sensing mechanism

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6300), p.664-669

2016

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Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel

X-ray structure of the mammalian GIRK2-βγ G-protein complex

Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 Å Resolution

Cryo-electron microscopy structure of the Slo2.2 Na+-activated K+ channel

Molecular structures of the human Slo1 K + channel in complex with β4

Molecular structure of an open human KATP channel

Chemistry of ion coordination and hydration revealed by a K + channel-Fab complex at 2.0 resolution

Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels

The mechanism of Gαq regulation of PLCβ-catalyzed PIP2 hydrolysis

Ligand-Dependent Structural States of a K+Channel Analyzed by Cryo-EM

The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel

Determining native-like membrane protein structures from cell membrane-derived vesicles

Structural Basis of Inward Rectification: Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 Å Resolution

The mechanism of Gα q regulation of PLCβ3 -catalyzed PIP2 hydrolysis

Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on the membrane surface

Structure of the Human BK Channel Ca²⁺-Activation Apparatus at 3.0 Å Resolution

Structural basis for gating the highconductance Ca^sup 2+^-activated K^sup +^ channel

Cryo-EM structure of the open highconductance Ca^sup 2+^-activated K^sup +^ channel

The Structural Basis of Voltage Sensing

Purification and Characterization of Three Inhibitors of Voltage-Dependent K+ Channels from Leiurus Quinquestriatus var. Hebraeus Venom

Structural Response of the Piezo Channel to Force Application at Different Frequencies

X-ray structure of the mammalian GIRK2-[beta][gamma] G-protein complex

X-ray structure of a CIC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity

Structural Response of the Piezo Channel Upon Application of Force

Structure of the voltage-gated K⁺ channel Eagl reveals an alternative voltage sensing mechanism

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