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G-quadruplexes in viruses: function and potential therapeutic applications

Nucleic acids research, 2014-11, Vol.42 (20), p.12352

2014

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Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV‑1 Integrase and Reverse Transcriptase Ribonuclease H Domain

Journal of medicinal chemistry, 2015-02, Vol.58 (4), p.1915-1928

2015

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Correction to 4‑Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV‑1

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6885-6885

2014

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Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)

Molecular pharmacology, 2011-10, Vol.80 (4), p.565-572

2011

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Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7315-7332

2017

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Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV‑1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8579-8598

2021

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6‑(1-Benzyl‑1H‑pyrrol-2-yl)-2,4-dioxo-5-hexenoic Acids as Dual Inhibitors of Recombinant HIV‑1 Integrase and Ribonuclease H, Synthesized by a Parallel Synthesis Approach

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8588-8598

2013

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Template requirements of Zika RNA polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA

Biochimie, 2022-04, Vol.195, p.71-76

2022

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Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration

Molecules (Basel, Switzerland), 2021-09, Vol.26 (17), p.5423

2021

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Biochemical and Pharmacological Analyses of HIV-1 Integrase Flexible Loop Mutants Resistant to Raltegravir

Biochemistry (Easton), 2010-05, Vol.49 (17), p.3715-3722

2010

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HIV Integrase Inhibitors: 20-Year Landmark and Challenges

Advances in Pharmacology, 2013, Vol.67, p.75-105

2013

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Bicyclic 1‑Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-Containing HIV‑1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant Integrase Mutants

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1573-1582

2014

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Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV‑1 Ribonuclease H Function of Reverse Transcriptase

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.798-805

2020

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4‑Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV‑1

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5190-5202

2014

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Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase

Journal of medicinal chemistry, 2014-04, Vol.57 (8), p.3223-3234

2014

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N‑Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase

Journal of medicinal chemistry, 2015-06, Vol.58 (11), p.4610-4623

2015

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Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.411-419

2012

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De novo RNA synthesis catalyzed by the Zika Virus RNA polymerase domain

Scientific reports, 2017-06, Vol.7 (1), p.2697-9, Article 2697

2017

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HIV-1 IN inhibitors: 2010 update and perspectives

Current topics in medicinal chemistry, 2009-08, Vol.9 (11), p.1016

2009

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Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75

Nucleic acids research, 2021-11, Vol.49 (19), p.11241

2021

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Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (28), p.1-e2202370119

2022

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Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening

Molecules (Basel, Switzerland), 2019-10, Vol.24 (20), p.3675

2019

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Resistance to integrase inhibitors

Viruses, 2010-07, Vol.2 (7), p.1347-1366

2010

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Cell-Permeable Stapled Peptides Based on HIV‑1 Integrase Inhibitors Derived from HIV‑1 Gene Products

ACS chemical biology, 2013-10, Vol.8 (10), p.2235-2244

2013

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Anticancer molecule AS1411 exhibits low nanomolar antiviral activity against HIV-1

Biochimie, 2015-11, Vol.118, p.173-175

2015

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G-quadruplexes in viruses: function and potential therapeutic applications

Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV‑1 Integrase and Reverse Transcriptase Ribonuclease H Domain

Correction to 4‑Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV‑1

Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)

Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors

Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV‑1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase

6‑(1-Benzyl‑1H‑pyrrol-2-yl)-2,4-dioxo-5-hexenoic Acids as Dual Inhibitors of Recombinant HIV‑1 Integrase and Ribonuclease H, Synthesized by a Parallel Synthesis Approach

Template requirements of Zika RNA polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA

Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration

Biochemical and Pharmacological Analyses of HIV-1 Integrase Flexible Loop Mutants Resistant to Raltegravir

HIV Integrase Inhibitors: 20-Year Landmark and Challenges

Bicyclic 1‑Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-Containing HIV‑1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant Integrase Mutants

Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV‑1 Ribonuclease H Function of Reverse Transcriptase

4‑Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV‑1

Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase

N‑Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase

Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity

De novo RNA synthesis catalyzed by the Zika Virus RNA polymerase domain

HIV-1 IN inhibitors: 2010 update and perspectives

Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75

Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction

Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening

Resistance to integrase inhibitors

Cell-Permeable Stapled Peptides Based on HIV‑1 Integrase Inhibitors Derived from HIV‑1 Gene Products

Anticancer molecule AS1411 exhibits low nanomolar antiviral activity against HIV-1

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