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The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

Progress in neuro-psychopharmacology & biological psychiatry, 2011-04, Vol.35 (3), p.702-721

2011

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C.03.03 New pharmacotherapeutic opportunities for the treatment of depression

European neuropsychopharmacology, 2013-10, Vol.23, p.S632-S632

Leonard, B.E

2013

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C.10.01 Evolved thinking in mood disorders: new insights into disease pathophysiology

European neuropsychopharmacology, 2012-10, Vol.22, p.S448-S448

Leonard, B.E

2012

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The HPA and immune axes in stress: the involvement of the serotonergic system

European psychiatry, 2005-10, Vol.20 Suppl 3, p.S302

Leonard, B E

2005

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C.07.01 Innovative antidepressant treatment targets

European neuropsychopharmacology, 2010, Vol.20, p.S641-S642

Leonard, B.E

2010

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Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients

Brain, behavior, and immunity, 2011-11, Vol.25 (8), p.1576-1581

2011

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The olfactory bulbectomized rat as a model of depression: An update

Pharmacology & therapeutics (Oxford), 1997, Vol.74 (3), p.299-316

1997

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P.1.08 Differential immune response to maternal separation stress in male and female prenatally-stressed juvenile rats

European neuropsychopharmacology, 2009, Vol.19, p.S9-S9

2009

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Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats

Pharmacology & therapeutics (Oxford), 1990, Vol.47 (1), p.21-34

1990

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S.1.1 Animal modeling of depressive disorders

European neuropsychopharmacology, 2005, Vol.15, p.S89-S91

Leonard, B.E.

2005

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Effects of antidepressants on cytokine production and actions

Brain, behavior, and immunity, 2002-10, Vol.16 (5), p.569-574

2002

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Inflammation Effects on Glutamate as a Pathway to Neuroprogression in Mood Disorders

Modern trends in pharmacopsychiatry, 2017, Vol.31, p.37

2017

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Innate Immune Memory: Implications for Microglial Function and Neuroprogression

Modern trends in pharmacopsychiatry, 2017, Vol.31, p.67

2017

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Towards an Integrated View of Early Molecular Changes Underlying Vulnerability to Social Stress in Psychosis

Modern trends in pharmacopsychiatry, 2017, Vol.31, p.96

2017

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An assessment of the effects of central interleukin-1 β, -2, -6, and tumor necrosis factor- α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat

Neuroscience, 1998-02, Vol.84 (3), p.923-933

1998

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The neuroprotective effect of tacrine on trimethyltin induced memory and muscarinic receptor dysfunction in the rat

Neurochemistry international, 1994-12, Vol.25 (6), p.555-566

1994

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Role of Inflammation in Depression: Implications for Phenomenology, Pathophysiology and Treatment

Inflammation in Psychiatry, 2013, Vol.28, p.33-48

2013

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Role of paroxetine in interferon-α-induced immune and behavioural changes in male Wistar rats

Journal of psychopharmacology (Oxford), 2007-11, Vol.21 (8), p.843-850

2007

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Cytokines and depression

European neuropsychopharmacology, 1998-11, Vol.8, p.S102-S103

Leonard, B.E.

1998

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Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls

Journal of affective disorders, 1994-04, Vol.30 (4), p.283-288

1994

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Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test

Psychoneuroendocrinology, 2003-04, Vol.28 (3), p.332-347

2003

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P.2.d.014 Effect of the selective COX-2 inhibitor, celecoxib, on brain cytokines in the olfactory bulbectomised rat model of depression

European neuropsychopharmacology, 2006, Vol.16, p.S340-S340

2006

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Cytokines, glucocorticoids and memory

Psychoneuroendocrinology, 2000, Vol.25, p.S30-S30

2000

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Sigma receptors, stress and immunomodulation

Psychoneuroendocrinology, 2000, Vol.25, p.S31-S31

2000

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Mechanisms of Action of Antidepressants

CNS drugs, 1995, Vol.4 (Supplement 1), p.1-12

Leonard, B.E.

1995

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The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

C.03.03 New pharmacotherapeutic opportunities for the treatment of depression

C.10.01 Evolved thinking in mood disorders: new insights into disease pathophysiology

The HPA and immune axes in stress: the involvement of the serotonergic system

C.07.01 Innovative antidepressant treatment targets

Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients

The olfactory bulbectomized rat as a model of depression: An update

P.1.08 Differential immune response to maternal separation stress in male and female prenatally-stressed juvenile rats

Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats

S.1.1 Animal modeling of depressive disorders

Effects of antidepressants on cytokine production and actions

Inflammation Effects on Glutamate as a Pathway to Neuroprogression in Mood Disorders

Innate Immune Memory: Implications for Microglial Function and Neuroprogression

Towards an Integrated View of Early Molecular Changes Underlying Vulnerability to Social Stress in Psychosis

An assessment of the effects of central interleukin-1 β, -2, -6, and tumor necrosis factor- α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat

The neuroprotective effect of tacrine on trimethyltin induced memory and muscarinic receptor dysfunction in the rat

Role of Inflammation in Depression: Implications for Phenomenology, Pathophysiology and Treatment

Role of paroxetine in interferon-α-induced immune and behavioural changes in male Wistar rats

Cytokines and depression

Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls

Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test

P.2.d.014 Effect of the selective COX-2 inhibitor, celecoxib, on brain cytokines in the olfactory bulbectomised rat model of depression

Cytokines, glucocorticoids and memory

Sigma receptors, stress and immunomodulation

Mechanisms of Action of Antidepressants

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