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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Cell stem cell, 2017-01, Vol.20 (1), p.135-148

2017

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Can cell and gene therapies improve cognitive symptoms in Parkinson's disease?

Journal of integrative neuroscience, 2022-04, Vol.21 (3), p.78-78

Lelos, Mariah J

2022

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Defining the unknowns for cell therapies in Parkinson's disease

Disease models & mechanisms, 2022-10, Vol.15 (10)

2022

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Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

Development (Cambridge), 2013-01, Vol.140 (2), p.301-312

2013

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Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Scientific reports, 2023-10, Vol.13 (1), p.17697-17697, Article 17697

2023

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Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Behavioural brain research, 2012-03, Vol.228 (1), p.30-43

2012

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Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2

EMBO molecular medicine, 2023-11, Vol.15 (11), p.e15984-e15984

2023

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Investigating cell therapies in animal models of Parkinson's and Huntington's disease: Current challenges and considerations

International review of neurobiology, 2022, Vol.166, p.159

Lelos, Mariah J

2022

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Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology

Biochemical and biophysical research communications, 2011-12, Vol.415 (4), p.656-661

2011

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Rethinking Functional Outcome Measures: The Development of a Novel Upper Limb Token Transfer Test to Assess Basal Ganglia Dysfunction

Frontiers in neuroscience, 2018-05, Vol.12, p.366-366

2018

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Do foetal transplant studies continue to be justified in Huntington's disease?

Neuronal signaling, 2021-12, Vol.5 (4), p.NS20210019-NS20210019

2021

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Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development

iScience, 2024-01, Vol.27 (1), p.108670-108670, Article 108670

2024

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c-Fos expression reveals aberrant neural network activity during cued fear conditioning in APPswe transgenic mice

Neurobiology of learning and memory, 2012-07, Vol.98 (1), p.1-11

2012

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Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function

Cell transplantation, 2016-04, Vol.25 (4), p.665-675

2016

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[ 18 F]Difluorocarbene for positron emission tomography

Nature (London), 2022-06, Vol.606 (7912), p.102-108

2022

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Spontaneous Graft‐Induced Dyskinesias Are Independent of 5‐HT Neurons and Levodopa Priming in a Model of Parkinson's Disease

Movement disorders, 2022-03, Vol.37 (3), p.613-619

2022

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Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

Experimental neurology, 2016-08, Vol.282, p.19-26

2016

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Neurite Outgrowth and Gene Expression Profile Correlate with Efficacy of Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts

Stem cells and development, 2023-07, Vol.32 (13-14), p.387

2023

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Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease

Cellular and molecular neurobiology, 2023-07, Vol.43 (5), p.2377-2384

2023

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β-Amyloid pathology alters neural network activation during retrieval of contextual fear memories in a mouse model of Alzheimer's disease

The European journal of neuroscience, 2014-05, Vol.39 (10), p.1690-1703

2014

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Do alpha-synuclein vector injections provide a better model of Parkinson's disease than the classic 6-hydroxydopamine model?

Experimental neurology, 2012-09, Vol.237 (1), p.36-42

2012

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Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats

Experimental neurology, 2013-09, Vol.247, p.485-495

2013

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Challenges in progressing cell therapies to the clinic for Huntington's disease: A review of the progress made with pluripotent stem cell derived medium spiny neurons

International review of neurobiology, 2022, Vol.166, p.1

2022

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Impaired sensitivity to Pavlovian stimulus–outcome learning after excitotoxic lesion of the ventrolateral neostriatum

Behavioural brain research, 2011-12, Vol.225 (2), p.522-528

2011

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Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?

Progress in Brain Research, 2012, Vol.200, p.113-142

2012

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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Can cell and gene therapies improve cognitive symptoms in Parkinson's disease?

Defining the unknowns for cell therapies in Parkinson's disease

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2

Investigating cell therapies in animal models of Parkinson's and Huntington's disease: Current challenges and considerations

Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology

Rethinking Functional Outcome Measures: The Development of a Novel Upper Limb Token Transfer Test to Assess Basal Ganglia Dysfunction

Do foetal transplant studies continue to be justified in Huntington's disease?

Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development

c-Fos expression reveals aberrant neural network activity during cued fear conditioning in APPswe transgenic mice

Direct Comparison of Rat- and Human-Derived Ganglionic Eminence Tissue Grafts on Motor Function

[ 18 F]Difluorocarbene for positron emission tomography

Spontaneous Graft‐Induced Dyskinesias Are Independent of 5‐HT Neurons and Levodopa Priming in a Model of Parkinson's Disease

Cognitive training modifies disease symptoms in a mouse model of Huntington's disease

Neurite Outgrowth and Gene Expression Profile Correlate with Efficacy of Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts

Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease

β-Amyloid pathology alters neural network activation during retrieval of contextual fear memories in a mouse model of Alzheimer's disease

Do alpha-synuclein vector injections provide a better model of Parkinson's disease than the classic 6-hydroxydopamine model?

Dopamine-rich grafts alleviate deficits in contralateral response space induced by extensive dopamine depletion in rats

Challenges in progressing cell therapies to the clinic for Huntington's disease: A review of the progress made with pluripotent stem cell derived medium spiny neurons

Impaired sensitivity to Pavlovian stimulus–outcome learning after excitotoxic lesion of the ventrolateral neostriatum

Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?

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