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Wnt signalling regulates adult hippocampal neurogenesis

Nature, 2005-10, Vol.437 (7063), p.1370-1375

2005

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A novel DYRK1A (Dual specificity tyrosine phosphorylation‐regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro

Journal of neurochemistry, 2015-05, Vol.133 (3), p.440-451

2015

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DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

The Journal of experimental medicine, 2015-06, Vol.212 (6), p.953-970

2015

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Etazolate, a neuroprotective drug linking GABAA receptor pharmacology to amyloid precursor protein processing

Journal of neurochemistry, 2008-07, Vol.106 (1), p.392-404

2008

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Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer

Endocrine-related cancer, 2011-04, Vol.18 (2), p.207-219

2011

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RAC1 Inhibition Targets Amyloid Precursor Protein Processing by γ-Secretase and Decreases Aβ Production in Vitro and in Vivo

The Journal of biological chemistry, 2005-11, Vol.280 (45), p.37516-37525

2005

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An Unusual Binding Model of the Methyl 9‑Anilinothiazolo[5,4‑f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases

Journal of medicinal chemistry, 2016-11, Vol.59 (22), p.10315-10321

2016

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Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part I

Molecules (Basel, Switzerland), 2014-09, Vol.19 (10), p.15546-15571

2014

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Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac

Blood, 2010-04, Vol.115 (14), p.2938-2946

2010

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Rap1-Rac1 circuits potentiate platelet activation

Arteriosclerosis, thrombosis, and vascular biology, 2012-02, Vol.32 (2), p.434

2012

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Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II

Molecules (Basel, Switzerland), 2014-09, Vol.19 (10), p.15411-15439

2014

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Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer

Oncotarget, 2017-03, Vol.8 (13), p.21806-21817

2017

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Plaie transfixiante de l'avant-bras par implantation d'un objet tranchant inhabituel: à propos d’un cas

The Pan African medical journal, 2021-07, Vol.39

2021

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Rare association of thermal burns of the knee and ankle with wounds of the patellar and achilles tendons

Burns open : an international open access journal for burn injuries, 2023-07, Vol.7 (3), p.64-67

2023

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Multiplex Antibody Detection for Noninvasive Genus-Level Diagnosis of Prosthetic Joint Infection

Journal of clinical microbiology, 2016-04, Vol.54 (4), p.1065-1073

2016

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Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease

Journal of Alzheimer's disease, 2012-01, Vol.32 (1), p.169

2012

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O3-05-02: EHT-0202: A neuroprotective and procognitive alpha-secretase stimulator targeted towards Alzheimer disease therapy

Alzheimer's & dementia, 2008-07, Vol.4 (4), p.T168-T168

2008

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Blood transcriptomic biomarkers of Alzheimer's disease patients treated with EHT 0202

Journal of Alzheimer's disease, 2013-01, Vol.34 (2), p.469

2013

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A Novel Immersive Anatomy Education System (Anat_Hub): Redefining Blended Learning for the Musculoskeletal System

Applied sciences, 2022-06, Vol.12 (11), p.5694

2022

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Assessment of the novel tubulin-binding agent EHT 6706 in combination with ionizing radiation or chemotherapy

Investigational new drugs, 2012-12, Vol.30 (6), p.2173-2186

2012

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Abstract 2620: 3D multicellular pancreatic cancer spheroids as drug screening tool for pharmacological evaluation of EHT 5372 and other Mirk/DYRK1B inhibitors

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.2620-2620

2014

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Structure–activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5594-5598

2009

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Vascular disrupting activity and the mechanism of action of EHT 6706, a novel anticancer tubulin polymerization inhibitor

Investigational new drugs, 2013-04, Vol.31 (2), p.304-319

2013

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Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

The American journal of pathology, 2012-02, Vol.180 (2), p.526-540

2012

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Abstract 1260: Alternative splicing studies for the identification of novel cancer markers and targets for antibody-based therapy

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1260-1260

2012

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Wnt signalling regulates adult hippocampal neurogenesis

A novel DYRK1A (Dual specificity tyrosine phosphorylation‐regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

Etazolate, a neuroprotective drug linking GABAA receptor pharmacology to amyloid precursor protein processing

Inhibition of the Rho GTPase, Rac1, decreases estrogen receptor levels and is a novel therapeutic strategy in breast cancer

RAC1 Inhibition Targets Amyloid Precursor Protein Processing by γ-Secretase and Decreases Aβ Production in Vitro and in Vivo

An Unusual Binding Model of the Methyl 9‑Anilinothiazolo[5,4‑f] quinazoline-2-carbimidates (EHT 1610 and EHT 5372) Confers High Selectivity for Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases

Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part I

Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac

Rap1-Rac1 circuits potentiate platelet activation

Design and synthesis of thiazolo[5,4-f]quinazolines as DYRK1A inhibitors, part II

Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer

Plaie transfixiante de l'avant-bras par implantation d'un objet tranchant inhabituel: à propos d’un cas

Rare association of thermal burns of the knee and ankle with wounds of the patellar and achilles tendons

Multiplex Antibody Detection for Noninvasive Genus-Level Diagnosis of Prosthetic Joint Infection

Validation of AclarusDx™, a blood-based transcriptomic signature for the diagnosis of Alzheimer's disease

O3-05-02: EHT-0202: A neuroprotective and procognitive alpha-secretase stimulator targeted towards Alzheimer disease therapy

Blood transcriptomic biomarkers of Alzheimer's disease patients treated with EHT 0202

A Novel Immersive Anatomy Education System (Anat_Hub): Redefining Blended Learning for the Musculoskeletal System

Assessment of the novel tubulin-binding agent EHT 6706 in combination with ionizing radiation or chemotherapy

Abstract 2620: 3D multicellular pancreatic cancer spheroids as drug screening tool for pharmacological evaluation of EHT 5372 and other Mirk/DYRK1B inhibitors

Structure–activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding

Vascular disrupting activity and the mechanism of action of EHT 6706, a novel anticancer tubulin polymerization inhibitor

Rac1b Increases with Progressive Tau Pathology within Cholinergic Nucleus Basalis Neurons in Alzheimer's Disease

Abstract 1260: Alternative splicing studies for the identification of novel cancer markers and targets for antibody-based therapy

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