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Hot topics in opioid pharmacology: mixed and biased opioids

British journal of anaesthesia : BJA, 2019-06, Vol.122 (6), p.e136-e145

2019

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Ketamine; history and role in anesthetic pharmacology

Neuropharmacology, 2022-09, Vol.216, p.109171-109171, Article 109171

2022

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Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

Molecules (Basel, Switzerland), 2020-08, Vol.25 (17), p.3870

2020

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Mixed mu-nociceptin/orphanin FQ opioid receptor agonists and the search for the analgesic holy grail

British journal of anaesthesia : BJA, 2019-06, Vol.122 (6), p.e95-e97

Lambert, David G.

2019

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Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis

BJA open, 2023-06, Vol.6, p.100141-100141, Article 100141

Lambert, David G.

2023

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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

PloS one, 2022-09, Vol.17 (9), p.e0274080-e0274080

2022

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Soluble Vascular Adhesion Protein 1 (sVAP-1) as a biomarker for pregnancy complications: A pilot study

PloS one, 2023-05, Vol.18 (5), p.e0284412-e0284412

2023

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Preclinical discovery and development of oliceridine (Olinvyk®) for the treatment of post-operative pain

Expert opinion on drug discovery, 2022-03, Vol.17 (3), p.215-223

2022

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Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors

PloS one, 2021-01, Vol.16 (4), p.e0250011-e0250011

2021

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Opioids and the COVID-19 pandemic: does chronic opioid use or misuse increase clinical vulnerability?

British journal of anaesthesia : BJA, 2020-10, Vol.125 (4), p.e382-e383

Lambert, David G.

2020

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Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12700

2022

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Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation

Molecules (Basel, Switzerland), 2020-12, Vol.26 (1), p.13

2020

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Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)

PloS one, 2016-06, Vol.11 (6), p.e0156897-e0156897

2016

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The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

Nature reviews. Drug discovery, 2008-08, Vol.7 (8), p.694-710

Lambert, David G

2008

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Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13)

European journal of pharmacology, 2017-01, Vol.794, p.115-126

2017

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Opioids, gliosis and central immunomodulation

Journal of anesthesia, 2018-10, Vol.32 (5), p.756-767

2018

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Danavorexton (TAK-925): an orexin receptor 2 agonist as a new ‘arousal’ agent

British journal of anaesthesia : BJA, 2024-03, Vol.132 (3), p.466-468

2024

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Opioids and cancer survival: are we looking in the wrong place?

BJA open, 2022-06, Vol.2, p.100010-100010, Article 100010

2022

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The Nociceptin/Orphanin FQ system is modulated in patients admitted to ICU with sepsis and after cardiopulmonary bypass

PloS one, 2013-10, Vol.8 (10), p.e76682-e76682

2013

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Can anesthetic techniques or drugs affect cancer recurrence in patients undergoing cancer surgery?

Journal of anesthesia, 2013-10, Vol.27 (5), p.731-741

2013

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Anaesthesiology in China. Response to Br J Anaesth 2019; 123: 559–64

British journal of anaesthesia : BJA, 2019-11, Vol.123 (5), p.e521-e522

Lambert, David G.

2019

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Anaesthesia-related drugs and SARS-CoV-2 infection

British journal of anaesthesia : BJA, 2021-07, Vol.127 (1), p.e32-e34

2021

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Propofol and SARS-CoV-2 infection

British journal of anaesthesia : BJA, 2020-12, Vol.125 (6), p.e475-e476

2020

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Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

BJA open, 2022-12, Vol.4, p.100110-100110, Article 100110

2022

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Properdin levels in human sepsis

Frontiers in immunology, 2015-02, Vol.6, p.24-24

2015

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Hot topics in opioid pharmacology: mixed and biased opioids

Ketamine; history and role in anesthetic pharmacology

Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

Mixed mu-nociceptin/orphanin FQ opioid receptor agonists and the search for the analgesic holy grail

Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

Soluble Vascular Adhesion Protein 1 (sVAP-1) as a biomarker for pregnancy complications: A pilot study

Preclinical discovery and development of oliceridine (Olinvyk®) for the treatment of post-operative pain

Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors

Opioids and the COVID-19 pandemic: does chronic opioid use or misuse increase clinical vulnerability?

Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation

Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13)

Opioids, gliosis and central immunomodulation

Danavorexton (TAK-925): an orexin receptor 2 agonist as a new ‘arousal’ agent

Opioids and cancer survival: are we looking in the wrong place?

The Nociceptin/Orphanin FQ system is modulated in patients admitted to ICU with sepsis and after cardiopulmonary bypass

Can anesthetic techniques or drugs affect cancer recurrence in patients undergoing cancer surgery?

Anaesthesiology in China. Response to Br J Anaesth 2019; 123: 559–64

Anaesthesia-related drugs and SARS-CoV-2 infection

Propofol and SARS-CoV-2 infection

Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

Properdin levels in human sepsis

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