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Novel Prodrugs of SN38 Using Multiarm Poly(ethylene glycol) Linkers

Bioconjugate chemistry, 2008-04, Vol.19 (4), p.849-859

2008

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Biodistribution and excretion of radiolabeled 40 kDa polyethylene glycol following intravenous administration in mice

Journal of pharmaceutical sciences, 2013-07, Vol.102 (7), p.2362-2370

2013

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Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11–Refractory Model

Clinical cancer research, 2008-03, Vol.14 (6), p.1888-1896

2008

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Expanding the Roles for Pregnane X Receptor in Cancer: Proliferation and Drug Resistance in Ovarian Cancer

Clinical cancer research, 2008-09, Vol.14 (17), p.5332-5340

2008

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High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

The Journal of infectious diseases, 2011-01, Vol.203 (2), p.175-179

2011

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Biodistribution and Excretion of Radiolabeled 40kDa Polyethylene Glycol Following Intravenous Administration in Mice

Journal of pharmaceutical sciences, 2013-07, Vol.102 (7), p.2362-2370

2013

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Utility of Poly(ethylene glycol) Conjugation To Create Prodrugs of Amphotericin B

Bioconjugate chemistry, 2003-05, Vol.14 (3), p.661-666

2003

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Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase

Microbiology (Society for General Microbiology), 2000-12, Vol.146 Pt 12, p.3129

2000

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Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding

FEMS microbiology letters, 2000-02, Vol.183 (2), p.209-214

2000

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Synthesis and Mode of Action of Hydrophobic Derivatives of the Glycopeptide Antibiotic Eremomycin and Des-(N-methyl-d-leucyl)eremomycin against Glycopeptide-Sensitive and -Resistant Bacteria

Journal of medicinal chemistry, 2002-03, Vol.45 (6), p.1340-1347

2002

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An unexpected amide bond cleavage: poly (ethylene glycol) transport forms of vancomycin. 2

European journal of medicinal chemistry, 2005-08, Vol.40 (8), p.798-804

2005

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Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation

Bioconjugate chemistry, 2006-05, Vol.17 (3), p.618-630

2006

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Differential antibacterial activity of moenomycin analogues on gram-positive bacteria

Bioorganic & medicinal chemistry letters, 2000-10, Vol.10 (20), p.2251-2254

2000

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PEG prodrugs of 6-mercaptopurine for parenteral administration using benzyl elimination of thiols

Oncology research, 2004, Vol.14 (9), p.455

2004

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Intestinal transport of gentamicin with a novel, glycosteroid drug transport agent

Pharmaceutical research, 1998-12, Vol.15 (12), p.1876-1881

1998

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Tumor Imaging with Technetium-99m-Labeled Hydrazinonicotinamide-Fab' Conjugates

The Journal of nuclear medicine (1978), 1997-01, Vol.38 (1), p.133-138

1997

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Tailoring structure–function and pharmacokinetic properties of single‐chain Fv proteins by site‐specific PEGylation

Protein engineering, 2003-10, Vol.16 (10), p.761-770

2003

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Engineering an Arginine Catabolizing Bioconjugate: Biochemical and Pharmacological Characterization of PEGylated Derivatives of Arginine Deiminase from Mycoplasma arthritidis

Bioconjugate chemistry, 2006-11, Vol.17 (6), p.1447-1459

2006

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Releasable PEGylation of Mesothelin Targeted Immunotoxin SS1P Achieves Single Dosage Complete Regression of a Human Carcinoma in Mice

Bioconjugate chemistry, 2007-05, Vol.18 (3), p.773-784

2007

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Marked Therapeutic Efficacy of a Novel Polyethyleneglycol-SN38 Conjugate, EZN-2208, in Xenograft Models of Non-Hodgkin's Lymphoma

Blood, 2007-11, Vol.110 (11), p.1397-1397

2007

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High-level conjugation of chelating agents onto immunoglobulins: use of an intermediary poly( l-lysine)-diethylenetriaminepentaacetic acid carrier

Biochimica et biophysica acta, 1986-10, Vol.883 (3), p.460-467

1986

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Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy

Journal of controlled release, 2007-06, Vol.119 (2), p.143-152

2007

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Rees-Mogg, gentleman thunderer

Sunday times (London, England : 1931), 2012-02, p.4-4

Longley, Clifford

2012

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Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding

FEMS microbiology letters, 2000-02, Vol.183 (2), p.209-214

2000

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Cationic Facial Amphiphiles: A Promising Class of Transfection Agents

Proceedings of the National Academy of Sciences - PNAS, 1996-02, Vol.93 (4), p.1585-1590

1996

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Novel Prodrugs of SN38 Using Multiarm Poly(ethylene glycol) Linkers

Biodistribution and excretion of radiolabeled 40 kDa polyethylene glycol following intravenous administration in mice

Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11–Refractory Model

Expanding the Roles for Pregnane X Receptor in Cancer: Proliferation and Drug Resistance in Ovarian Cancer

High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

Biodistribution and Excretion of Radiolabeled 40kDa Polyethylene Glycol Following Intravenous Administration in Mice

Utility of Poly(ethylene glycol) Conjugation To Create Prodrugs of Amphotericin B

Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase

Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding

Synthesis and Mode of Action of Hydrophobic Derivatives of the Glycopeptide Antibiotic Eremomycin and Des-(N-methyl-d-leucyl)eremomycin against Glycopeptide-Sensitive and -Resistant Bacteria

An unexpected amide bond cleavage: poly (ethylene glycol) transport forms of vancomycin. 2

Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation

Differential antibacterial activity of moenomycin analogues on gram-positive bacteria

PEG prodrugs of 6-mercaptopurine for parenteral administration using benzyl elimination of thiols

Intestinal transport of gentamicin with a novel, glycosteroid drug transport agent

Tumor Imaging with Technetium-99m-Labeled Hydrazinonicotinamide-Fab' Conjugates

Tailoring structure–function and pharmacokinetic properties of single‐chain Fv proteins by site‐specific PEGylation

Engineering an Arginine Catabolizing Bioconjugate: Biochemical and Pharmacological Characterization of PEGylated Derivatives of Arginine Deiminase from Mycoplasma arthritidis

Releasable PEGylation of Mesothelin Targeted Immunotoxin SS1P Achieves Single Dosage Complete Regression of a Human Carcinoma in Mice

Marked Therapeutic Efficacy of a Novel Polyethyleneglycol-SN38 Conjugate, EZN-2208, in Xenograft Models of Non-Hodgkin's Lymphoma

High-level conjugation of chelating agents onto immunoglobulins: use of an intermediary poly( l-lysine)-diethylenetriaminepentaacetic acid carrier

Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy

Rees-Mogg, gentleman thunderer

Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding

Cationic Facial Amphiphiles: A Promising Class of Transfection Agents

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