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WWC Proteins: Important Regulators of Hippo Signaling in Cancer

Cancers, 2021-01, Vol.13 (2), p.306

2021

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Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

Nature communications, 2021-06, Vol.12 (1), p.3624-17, Article 3624

2021

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The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice

Cell death & disease, 2021-01, Vol.12 (1), p.117-117, Article 117

2021

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Regulation of AMPA Receptor Function by the Human Memory-Associated Gene KIBRA

Neuron (Cambridge, Mass.), 2011-09, Vol.71 (6), p.1022-1029

2011

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Evolutionary and molecular facts link the WWC protein family to Hippo signaling

Molecular biology and evolution, 2014-07, Vol.31 (7), p.1710-1723

2014

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Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice

International journal of molecular sciences, 2021-05, Vol.22 (10), p.5321

2021

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The Vac14-interaction Network Is Linked to Regulators of the Endolysosomal and Autophagic Pathway

Molecular & cellular proteomics, 2014-06, Vol.13 (6), p.1397-1411

2014

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An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

PLoS biology, 2009-11, Vol.7 (11), p.e1000235-e1000235

2009

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Lasp-1 regulates podosome function

PloS one, 2012-04, Vol.7 (4), p.e35340-e35340

2012

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SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA

Journal of neurochemistry, 2008-04, Vol.105 (2), p.351-359

2008

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Characterization of KIBRA, a novel WW domain-containing protein

Biochemical and biophysical research communications, 2003-01, Vol.300 (4), p.862-867

2003

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Essential Role of KIBRA in Co-activator Function of Dynein Light Chain 1 in Mammalian Cells

The Journal of biological chemistry, 2006-07, Vol.281 (28), p.19092-19099

2006

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Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring

Journal of neurochemistry, 2006-03, Vol.96 (6), p.1659-1666

2006

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WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis

The Journal of pathology, 2017-08, Vol.242 (4), p.435-447

2017

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Intrinsic disorder and amino acid specificity modulate binding of the WW2 domain in kidney and brain protein (KIBRA) to synaptopodin

The Journal of biological chemistry, 2019-11, Vol.294 (46), p.17383-17394

2019

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The Nebulin Family LIM and SH3 Proteins Regulate Postsynaptic Development and Function

The Journal of neuroscience, 2020-01, Vol.40 (3), p.526-541

2020

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KIBRA: In the brain and beyond

Cellular signalling, 2014-07, Vol.26 (7), p.1392-1399

2014

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Expression of synaptopodin in endothelial cells exposed to laminar shear stress and its role in endothelial wound healing

FEBS letters, 2014-03, Vol.588 (6), p.1024-1030

2014

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Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)–ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration

Cellular signalling, 2014-02, Vol.26 (2), p.343-351

2014

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WWC2 expression in the testis: Implications for spermatogenesis and male fertility

The FASEB journal, 2023-05, Vol.37 (5), p.e22912-n/a

2023

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WW and C2 domain–containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway

Hepatology (Baltimore, Md.), 2018-04, Vol.67 (4), p.1546-1559

2018

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WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma

Journal of cellular and molecular medicine, 2017-12, Vol.21 (12), p.3718-3729

2017

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KIBRA connects Hippo signaling and cancer

Experimental cell research, 2021-06, Vol.403 (2), p.112613-112613, Article 112613

2021

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Nuclear YAP localization as a key regulator of podocyte function

Cell death & disease, 2018-08, Vol.9 (9), p.850-14, Article 850

2018

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WWC3 inhibits epithelial-mesenchymal transition of lung cancer by activating Hippo-YAP signaling

OncoTargets and therapy, 2018-01, Vol.11, p.2581-2591

2018

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WWC Proteins: Important Regulators of Hippo Signaling in Cancer

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice

Regulation of AMPA Receptor Function by the Human Memory-Associated Gene KIBRA

Evolutionary and molecular facts link the WWC protein family to Hippo signaling

Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice

The Vac14-interaction Network Is Linked to Regulators of the Endolysosomal and Autophagic Pathway

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

Lasp-1 regulates podosome function

SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA

Characterization of KIBRA, a novel WW domain-containing protein

Essential Role of KIBRA in Co-activator Function of Dynein Light Chain 1 in Mammalian Cells

Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring

WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis

Intrinsic disorder and amino acid specificity modulate binding of the WW2 domain in kidney and brain protein (KIBRA) to synaptopodin

The Nebulin Family LIM and SH3 Proteins Regulate Postsynaptic Development and Function

KIBRA: In the brain and beyond

Expression of synaptopodin in endothelial cells exposed to laminar shear stress and its role in endothelial wound healing

Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)–ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration

WWC2 expression in the testis: Implications for spermatogenesis and male fertility

WW and C2 domain–containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway

WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma

KIBRA connects Hippo signaling and cancer

Nuclear YAP localization as a key regulator of podocyte function

WWC3 inhibits epithelial-mesenchymal transition of lung cancer by activating Hippo-YAP signaling

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