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Theodor Fontane und das Erbe der Aufklärung

1, 2021

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Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale

Chemical communications (Cambridge, England), 2012-01, Vol.48 (48), p.6001-6003

2012

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Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Microbial cell factories, 2015-06, Vol.14 (1), p.82-82, Article 82

2015

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Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1H-indazole (benzpyrazole)

Journal of analytical science and technology, 2017-04, Vol.8 (1), p.1-7, Article 10

2017

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Recombinant human cytochrome P450 monooxygenases for drug metabolite synthesis

Biotechnology and bioengineering, 2010-08, Vol.106 (5), p.699-706

2010

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Gas-Phase Rearrangement of the O -Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N -Glucuronide

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.189-193

2019

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Chemo-enzymatic approaches for the creation of novel chiral building blocks and reagents for pharmaceutical applications

Journal of molecular catalysis. B, Enzymatic, 2002-12, Vol.19-20, p.55-66

2002

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Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid

Advanced synthesis & catalysis, 2003-06, Vol.345 (6-7), p.825-829

2003

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A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s

Biotechnology and bioengineering, 2018-09, Vol.115 (9), p.2156-2166

2018

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Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis

Journal of biotechnology, 2016-10, Vol.235, p.3-10

2016

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Non‐clinical characterization of the disposition of EMA401, a novel small molecule angiotensin II type 2 receptor (AT2R) antagonist

Biopharmaceutics & drug disposition, 2020-04, Vol.41 (4-5), p.166-183

2020

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Metabolism and disposition of the metabotropic glutamate receptor 5 antagonist (mGluR5) mavoglurant (AFQ056) in healthy subjects

Drug metabolism and disposition, 2013-09, Vol.41 (9), p.1626

2013

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Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans

Drug metabolism and disposition, 2016-05, Vol.44 (5), p.653-664

2016

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Syk inhibitors with high potency in presence of blood

Bioorganic & medicinal chemistry letters, 2014-05, Vol.24 (10), p.2278-2282

2014

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Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589)

Drug metabolism and disposition, 2012-05, Vol.40 (5), p.1041

2012

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Production of Recombinant Human Aldehyde Oxidase in Escherichia coli and Optimization of Its Application for the Preparative Synthesis of Oxidized Drug Metabolites

ChemCatChem, 2014-04, Vol.6 (4), p.1028-1042

2014

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Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scaleElectronic supplementary information (ESI) available. See DOI: 10.1039/c2cc17878h

2012-05

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Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

New biotechnology, 2014-07, Vol.31, p.S82-S82

2014

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Preparation of 10,11-Epoxy-carbamazepine and 10,11-Dihydro-10-hydroxy-carbamazepine by Microbial Epoxidation and Hydroxylation

Bioscience, biotechnology, and biochemistry, 1993, Vol.57 (9), p.1589-1590

1993

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Preparation of Drug Metabolites Using Fungal and Bacterial Strains

Modern Biooxidation, 2007, p.211-232

2007

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Reaction engineering aspects of activated sugar production. CMP-Neu5Ac as an example

Annals of the New York Academy of Sciences, 1996-10, Vol.799 (1), p.577-583

1996

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N-Acetylneuraminic Acid From a Rare Chemical from Natural Sources to a Multikilogram Enzymatic Synthesis for Industrial Application

Annals of the New York Academy of Sciences, 1995-03, Vol.750 (1), p.300-305

1995

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Isolation and characterization of N-acetyldehydroleucine acylase, a new enzyme from Zoogloea ramigera

Journal of fermentation and bioengineering, 1992-01, Vol.73 (2), p.99-107

1992

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Oxidations

Practical Methods for Biocatalysis and Biotransformations 3, 2016, p.1-1

2016

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Isolation and classification of acetic acid bacteria from high percentage vinegar fermentations

Applied microbiology and biotechnology, 1989, Vol.30 (1), p.47-52

1989

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Theodor Fontane und das Erbe der Aufklärung

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1H-indazole (benzpyrazole)

Recombinant human cytochrome P450 monooxygenases for drug metabolite synthesis

Gas-Phase Rearrangement of the O -Glucuronide of Vildagliptin Forms Product-Ion Fragments Suggesting Wrongly an N -Glucuronide

Chemo-enzymatic approaches for the creation of novel chiral building blocks and reagents for pharmaceutical applications

Preparative Enzymatic Synthesis of the Acylglucuronide of Mycophenolic Acid

A novel cytochrome P450 mono‐oxygenase from Streptomyces platensis resembles activities of human drug metabolizing P450s

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis

Non‐clinical characterization of the disposition of EMA401, a novel small molecule angiotensin II type 2 receptor (AT2R) antagonist

Metabolism and disposition of the metabotropic glutamate receptor 5 antagonist (mGluR5) mavoglurant (AFQ056) in healthy subjects

Identification of Three Novel Ring Expansion Metabolites of KAE609, a New Spiroindolone Agent for the Treatment of Malaria, in Rats, Dogs, and Humans

Syk inhibitors with high potency in presence of blood

Biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589)

Production of Recombinant Human Aldehyde Oxidase in Escherichia coli and Optimization of Its Application for the Preparative Synthesis of Oxidized Drug Metabolites

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scaleElectronic supplementary information (ESI) available. See DOI: 10.1039/c2cc17878h

Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

Preparation of 10,11-Epoxy-carbamazepine and 10,11-Dihydro-10-hydroxy-carbamazepine by Microbial Epoxidation and Hydroxylation

Preparation of Drug Metabolites Using Fungal and Bacterial Strains

Reaction engineering aspects of activated sugar production. CMP-Neu5Ac as an example

N-Acetylneuraminic Acid From a Rare Chemical from Natural Sources to a Multikilogram Enzymatic Synthesis for Industrial Application

Isolation and characterization of N-acetyldehydroleucine acylase, a new enzyme from Zoogloea ramigera

Oxidations

Isolation and classification of acetic acid bacteria from high percentage vinegar fermentations

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