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Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase

Journal of the American Chemical Society, 2020-10, Vol.142 (41), p.17413-17424

2020

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The impact of the clinical CYP11B2 mutation V386A strongly depends on the enzyme’s genetic background

Endocrine Journal, 2017, Vol.64(4), pp.457-461

2017

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Kinetic solvent isotope effect in steady-state turnover by CYP19A1 suggests involvement of Compound 1 for both hydroxylation and aromatization steps

FEBS letters, 2014-08, Vol.588 (17), p.3117-3122

2014

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A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56

Organic & biomolecular chemistry, 2016-01, Vol.14 (13), p.3385-3393

2016

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Regioselective hydroxylation of norisoprenoids by CYP109D1 from Sorangium cellulosum So ce56

Applied microbiology and biotechnology, 2010-09, Vol.88 (2), p.485-495

2010

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Investigating the effect of available redox protein ratios for the conversion of a steroid by a myxobacterial CYP260A1

FEBS letters, 2017-04, Vol.591 (8), p.1126-1140

2017

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Investigating the effect of available redox protein ratios for the conversion of a steroid by a myxobacterial CYP 260A1

FEBS letters, 2017-04, Vol.591 (8), p.1126-1140

2017

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Biocatalytic role of cytochrome P450s to produce antibiotics: A review

Biotechnology and bioengineering, 2023-12, Vol.120 (12), p.3465-3492

2023

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Identification of new substrates for the CYP106A1-mediated 11-oxidation and investigation of the reaction mechanism

FEBS letters, 2015-08, Vol.589 (18), p.2320-2326

2015

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Conversions of tricyclic antidepressants and antipsychotics with selected P450s from Sorangium cellulosum So ce56

Drug metabolism and disposition, 2015-03, Vol.43 (3), p.392-399

2015

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Investigating the roles of T224 and T232 in the oxidation of cinnamaldehyde catalyzed by myxobacterial CYP260B1

FEBS letters, 2017-01, Vol.591 (1), p.39-46

2017

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Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1)

The Journal of steroid biochemistry and molecular biology, 2017-06, Vol.170, p.2-18

2017

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Genome Mining in Sorangium cellulosum So ce56

The Journal of biological chemistry, 2009-10, Vol.284 (42), p.28590-28598

2009

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Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis

Applied microbiology and biotechnology, 2010-06, Vol.87 (2), p.595-607

2010

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Investigating the roles of T224 and T232 in the oxidation of cinnamaldehyde catalyzed by myxobacterial CYP 260B1

FEBS letters, 2017-01, Vol.591 (1), p.39-46

2017

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Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases

Angewandte Chemie (International ed.), 2023-05, Vol.62 (20), p.e202210254-n/a

International ed. in English, 2023

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Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1α‐hydroxylation of a mineralocorticoid

FEBS letters, 2016-12, Vol.590 (24), p.4638-4648

2016

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Epoxidation and Late-Stage C–H Functionalization by P450 TamI Are Mediated by Variant Heme-Iron Oxidizing Species

ACS catalysis, 2022-03, Vol.12 (6), p.3731-3742

2022

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Kinetic Solvent Isotope Effect in Human P450 CYP17A1-Mediated Androgen Formation: Evidence for a Reactive Peroxoanion Intermediate

Journal of the American Chemical Society, 2013-11, Vol.135 (44), p.16245-16247

2013

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Active site proton delivery and the lyase activity of human CYP17A1

Biochemical and biophysical research communications, 2014-01, Vol.443 (1), p.179-184

2014

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Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C–H Functionalization and Epoxidation of Tirandamycin Antibiotics

ACS catalysis, 2021-07, Vol.11 (13), p.8304-8316

2021

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Substrate Hunting for the Myxobacterial CYP260A1 Revealed New 1[alpha]-Hydroxylated Products from C-19 Steroids

Chembiochem : a European journal of chemical biology, 2016-01, Vol.17 (1), p.90

2016

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Engineered Production of Hapalindole Alkaloids in the Cyanobacterium Synechococcus sp. UTEX 2973

ACS synthetic biology, 2019-08, Vol.8 (8), p.1941-1951

2019

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CYP267A1 and CYP267B1 from Sorangium cellulosum So ce56 are Highly Versatile Drug Metabolizers

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.495-504

2016

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A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs

ACS chemical biology, 2020-02, Vol.15 (2), p.524-532

2020

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Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase

The impact of the clinical CYP11B2 mutation V386A strongly depends on the enzyme’s genetic background

Kinetic solvent isotope effect in steady-state turnover by CYP19A1 suggests involvement of Compound 1 for both hydroxylation and aromatization steps

A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56

Regioselective hydroxylation of norisoprenoids by CYP109D1 from Sorangium cellulosum So ce56

Investigating the effect of available redox protein ratios for the conversion of a steroid by a myxobacterial CYP260A1

Investigating the effect of available redox protein ratios for the conversion of a steroid by a myxobacterial CYP 260A1

Biocatalytic role of cytochrome P450s to produce antibiotics: A review

Identification of new substrates for the CYP106A1-mediated 11-oxidation and investigation of the reaction mechanism

Conversions of tricyclic antidepressants and antipsychotics with selected P450s from Sorangium cellulosum So ce56

Investigating the roles of T224 and T232 in the oxidation of cinnamaldehyde catalyzed by myxobacterial CYP260B1

Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1)

Genome Mining in Sorangium cellulosum So ce56

Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis

Investigating the roles of T224 and T232 in the oxidation of cinnamaldehyde catalyzed by myxobacterial CYP 260B1

Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases

Structural characterization of CYP260A1 from Sorangium cellulosum to investigate the 1α‐hydroxylation of a mineralocorticoid

Epoxidation and Late-Stage C–H Functionalization by P450 TamI Are Mediated by Variant Heme-Iron Oxidizing Species

Kinetic Solvent Isotope Effect in Human P450 CYP17A1-Mediated Androgen Formation: Evidence for a Reactive Peroxoanion Intermediate

Active site proton delivery and the lyase activity of human CYP17A1

Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C–H Functionalization and Epoxidation of Tirandamycin Antibiotics

Substrate Hunting for the Myxobacterial CYP260A1 Revealed New 1[alpha]-Hydroxylated Products from C-19 Steroids

Engineered Production of Hapalindole Alkaloids in the Cyanobacterium Synechococcus sp. UTEX 2973

CYP267A1 and CYP267B1 from Sorangium cellulosum So ce56 are Highly Versatile Drug Metabolizers

A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs

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