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Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma

Blood, 2010-07, Vol.116 (3), p.406-417

2010

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ETV6–NTRK3 as a therapeutic target of small molecule inhibitor PKC412

Biochemical and biophysical research communications, 2012-12, Vol.429 (1-2), p.87-92

2012

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Phase II study of FLAGM (fludarabine + high-dose cytarabine + granulocyte colony-stimulating factor + mitoxantrone) for relapsed or refractory acute myeloid leukemia

International journal of hematology, 2019-04, Vol.109 (4), p.418-425

2019

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Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells

PloS one, 2013-06, Vol.8 (6), p.e66378

2013

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The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activity in Vitro and in Vivo by Down-regulating the Expression of Class I Histone Deacetylases

The Journal of biological chemistry, 2013-08, Vol.288 (35), p.25593-25602

2013

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Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies

PloS one, 2014-03, Vol.9 (3), p.e90675

2014

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Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma

Journal of investigative dermatology, 2008-06, Vol.128 (6), p.1506-1516

2008

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Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding

PloS one, 2013-04, Vol.8 (4), p.e60649-e60649

2013

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Apaf-1 Is a Mediator of E2F-1-induced Apoptosis

The Journal of biological chemistry, 2002-10, Vol.277 (42), p.39760-39768

2002

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Preventive effect of Kampo medicine (Hangeshashin-to) against irinotecan-induced diarrhea in advanced non-small-cell lung cancer

Cancer chemotherapy and pharmacology, 2003-05, Vol.51 (5), p.403-406

2003

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Phosphorylation of Bcl-2 Protein by CDC2 Kinase during G2/M Phases and Its Role in Cell Cycle Regulation

The Journal of biological chemistry, 2000-07, Vol.275 (28), p.21661-21667

2000

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The Cytotoxic Effects of Gemtuzumab Ozogamicin (Mylotarg) in Combination with Conventional Antileukemic Agents by Isobologram Analysis In Vitro

Anticancer research, 2009-11, Vol.29 (11), p.4589-4596

2009

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Phase II study of weekly chemotherapy with paclitaxel and gemcitabine as second-line treatment for advanced non-small cell lung cancer after treatment with platinum-based chemotherapy

Cancer chemotherapy and pharmacology, 2007-07, Vol.60 (2), p.189-195

2007

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Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells

Oncogene, 2001-12, Vol.20 (57), p.8249-8257

2001

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Relative importance of apoptosis and cell cycle blockage in the synergistic effect of combined R115777 and imatinib treatment in BCR/ABL-positive cell lines

Biochemical pharmacology, 2005-06, Vol.69 (11), p.1585-1594

2005

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Depsipeptide Enhances Imatinib Mesylate-induced Apoptosis of Bcr-Abl-positive Cells and Ectopic Expression of Cyclin D1, c-Myc or Active MEK Abrogates this Effect

Anticancer research, 2004-09, Vol.24 (5A), p.2705-2712

2004

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Phase I Trial of FLAGM with High Doses of Cytosine Arabinoside for Relapsed, Refractory Acute Myeloid Leukemia : Study of the Japan Adult Leukemia Study Group (JALSG)

International journal of hematology, 2007-11, Vol.86 (4), p.343-347

2007

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Schedule-dependent synergism and antagonism between pemetrexed and paclitaxel in human carcinoma cell lines in vitro

Cancer chemotherapy and pharmacology, 2004-12, Vol.54 (6), p.505-513

2004

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Schedule‐dependent Synergism and Antagonism between Raltitrexed (“Tomudex”) and Methotrexate in Human Colon Cancer Cell Lines in vitro

Cancer science, 2001-01, Vol.92 (1), p.74-82

2001

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Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells

Leukemia research, 2004-06, Vol.28 (6), p.623-629

2004

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In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents

Blood, 2001-04, Vol.97 (7), p.1999-2007

2001

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In vitro schedule-dependent interaction between paclitaxel and SN-38 (the active metabolite of irinotecan) in human carcinoma cell lines

Cancer chemotherapy and pharmacology, , Vol.42 (2), p.91-98

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Simultaneous Intraluminal Thermobrachytherapy: An in vitro Study

Cancer science, 2001-08, Vol.92 (8), p.904-910

2001

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Synergistic antitumor activity of the novel SN‐38‐incorporating polymeric micelles, NK012, combined with 5‐fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5‐fluorouracil

International journal of cancer, 2008-05, Vol.122 (9), p.2148-2153

2008

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Establishment and characterization of A novel Philadelphia-chromosome positive chronic myeloid leukemia cell line, TCC-S, expressing P210 and P190 BCR/ABL transcripts but missing normal ABL gene

Human cell : official journal of Human Cell Research Society, 2005-03, Vol.18 (1), p.25-33

2005

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Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma

ETV6–NTRK3 as a therapeutic target of small molecule inhibitor PKC412

Phase II study of FLAGM (fludarabine + high-dose cytarabine + granulocyte colony-stimulating factor + mitoxantrone) for relapsed or refractory acute myeloid leukemia

Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells

The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activity in Vitro and in Vivo by Down-regulating the Expression of Class I Histone Deacetylases

Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies

Transcriptional Modulation Using HDACi Depsipeptide Promotes Immune Cell-Mediated Tumor Destruction of Murine B16 Melanoma

Homopiperazine derivatives as a novel class of proteasome inhibitors with a unique mode of proteasome binding

Apaf-1 Is a Mediator of E2F-1-induced Apoptosis

Preventive effect of Kampo medicine (Hangeshashin-to) against irinotecan-induced diarrhea in advanced non-small-cell lung cancer

Phosphorylation of Bcl-2 Protein by CDC2 Kinase during G2/M Phases and Its Role in Cell Cycle Regulation

The Cytotoxic Effects of Gemtuzumab Ozogamicin (Mylotarg) in Combination with Conventional Antileukemic Agents by Isobologram Analysis In Vitro

Phase II study of weekly chemotherapy with paclitaxel and gemcitabine as second-line treatment for advanced non-small cell lung cancer after treatment with platinum-based chemotherapy

Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells

Relative importance of apoptosis and cell cycle blockage in the synergistic effect of combined R115777 and imatinib treatment in BCR/ABL-positive cell lines

Depsipeptide Enhances Imatinib Mesylate-induced Apoptosis of Bcr-Abl-positive Cells and Ectopic Expression of Cyclin D1, c-Myc or Active MEK Abrogates this Effect

Phase I Trial of FLAGM with High Doses of Cytosine Arabinoside for Relapsed, Refractory Acute Myeloid Leukemia : Study of the Japan Adult Leukemia Study Group (JALSG)

Schedule-dependent synergism and antagonism between pemetrexed and paclitaxel in human carcinoma cell lines in vitro

Schedule‐dependent Synergism and Antagonism between Raltitrexed (“Tomudex”) and Methotrexate in Human Colon Cancer Cell Lines in vitro

Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells

In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents

In vitro schedule-dependent interaction between paclitaxel and SN-38 (the active metabolite of irinotecan) in human carcinoma cell lines

Simultaneous Intraluminal Thermobrachytherapy: An in vitro Study

Synergistic antitumor activity of the novel SN‐38‐incorporating polymeric micelles, NK012, combined with 5‐fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5‐fluorouracil

Establishment and characterization of A novel Philadelphia-chromosome positive chronic myeloid leukemia cell line, TCC-S, expressing P210 and P190 BCR/ABL transcripts but missing normal ABL gene

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