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Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands

Developmental cell, 2017-01, Vol.40 (2), p.193-201

2017

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Nanodomains can persist at physiologic temperature in plasma membrane vesicles and be modulated by altering cell lipids[S]

Journal of lipid research, 2020-05, Vol.61 (5), p.758-766

2020

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Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation

Journal of lipid research, 2022-01, Vol.63 (1), p.100155-100155, Article 100155

2022

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Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6331), p.1320-1324

2017

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Induction of Ordered Lipid Raft Domain Formation by Loss of Lipid Asymmetry

Biophysical journal, 2020-08, Vol.119 (3), p.483-492

2020

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Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2

The Journal of biological chemistry, 2020-10, Vol.295 (43), p.14710-14722

2020

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Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity

PloS one, 2019-10, Vol.14 (10), p.e0223572-e0223572

2019

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Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)

Hepatology (Baltimore, Md.), 2016-02, Vol.63 (2), p.550-565

2016

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O-Glucose Trisaccharide Is Present at High but Variable Stoichiometry at Multiple Sites on Mouse Notch1

The Journal of biological chemistry, 2011-09, Vol.286 (36), p.31623-31637

2011

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A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

Science (American Association for the Advancement of Science), 2012-11, Vol.338 (6111), p.1229-1232

2012

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Analyzing the posttranslational modification status of Notch using mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2014-01, Vol.1187, p.209

2014

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O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function

PloS one, 2014-02, Vol.9 (2), p.e88571-e88571

2014

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HNK-1 Glyco-epitope Regulates the Stability of the Glutamate Receptor Subunit GluR2 on the Neuronal Cell Surface

The Journal of biological chemistry, 2009-10, Vol.284 (44), p.30209-30217

2009

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Expression and Function of the HNK-1 Carbohydrate

Journal of biochemistry (Tokyo), 2008-06, Vol.143 (6), p.719-724

2008

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Cyclodextrin phospholipid exchange alters viral membrane properties and infectivity

Biophysical journal, 2024-02, Vol.123 (3), p.97a-97a

2024

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Preparation and utility of asymmetric lipid vesicles for studies of perfringolysin O-lipid interactions

Methods in enzymology, 2021, Vol.649, p.253

2021

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What Determines Fringe Specificity for a Notch EGF?

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Nanodomains Persist to much Higher Temperatures than Large Scale Phase Separation in Giant Plasma Membrane Vesicles and Can Respond Differently to Alterations of Plasma Membrane Lipid Composition

Biophysical journal, 2020-02, Vol.118 (3), p.226a-227a

2020

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Structural Basis for Acceptor Substrate Recognition of a Human Glucuronyltransferase, GlcAT-P, an Enzyme Critical in the Biosynthesis of the Carbohydrate Epitope HNK-1

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22693-22703

2004

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Laminin-1 is a novel carrier glycoprotein for the nonsulfated HNK-1 epitope in mouse kidney

Glycobiology (Oxford), 2008-04, Vol.18 (4), p.331-338

2008

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Involvement of HNK-1 glyco-epitope in the spine morphogenesis

Neuroscience research, 2009, Vol.65, p.S82-S82

2009

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Efficient Replacement of Outer Leaflet Lipids of Plasma Membrane using Exogenous Lipids with Minimal Cell Damage

Biophysical journal, 2019-02, Vol.116 (3), p.363a-363a

2019

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Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

Developmental biology, 2022-07, Vol.487, p.42-56

2022

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Purification and characterization of two recombinant human glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate in Escherichia coli

Protein expression and purification, 2004-05, Vol.35 (1), p.111-119

2004

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Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion

Developmental biology, 2016-08, Vol.416 (1), p.111-122

2016

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Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands

Nanodomains can persist at physiologic temperature in plasma membrane vesicles and be modulated by altering cell lipids[S]

Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

Induction of Ordered Lipid Raft Domain Formation by Loss of Lipid Asymmetry

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2

Replacing plasma membrane outer leaflet lipids with exogenous lipid without damaging membrane integrity

Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)

O-Glucose Trisaccharide Is Present at High but Variable Stoichiometry at Multiple Sites on Mouse Notch1

A Mutation in EGF Repeat-8 of Notch Discriminates Between Serrate/Jagged and Delta Family Ligands

Analyzing the posttranslational modification status of Notch using mass spectrometry

O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function

HNK-1 Glyco-epitope Regulates the Stability of the Glutamate Receptor Subunit GluR2 on the Neuronal Cell Surface

Expression and Function of the HNK-1 Carbohydrate

Cyclodextrin phospholipid exchange alters viral membrane properties and infectivity

Preparation and utility of asymmetric lipid vesicles for studies of perfringolysin O-lipid interactions

What Determines Fringe Specificity for a Notch EGF?

Nanodomains Persist to much Higher Temperatures than Large Scale Phase Separation in Giant Plasma Membrane Vesicles and Can Respond Differently to Alterations of Plasma Membrane Lipid Composition

Structural Basis for Acceptor Substrate Recognition of a Human Glucuronyltransferase, GlcAT-P, an Enzyme Critical in the Biosynthesis of the Carbohydrate Epitope HNK-1

Laminin-1 is a novel carrier glycoprotein for the nonsulfated HNK-1 epitope in mouse kidney

Involvement of HNK-1 glyco-epitope in the spine morphogenesis

Efficient Replacement of Outer Leaflet Lipids of Plasma Membrane using Exogenous Lipids with Minimal Cell Damage

Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

Purification and characterization of two recombinant human glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate in Escherichia coli

Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion

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