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Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol

International Journal of Endocrinology, 2015-01, Vol.2015, p.479157-7

2015

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Role of FTO in Adipocyte Development and Function: Recent Insights

International Journal of Endocrinology, 2015-01, Vol.2015, p.521381-7

2015

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Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State

International Journal of Endocrinology, 2015-01, Vol.2015, p.915243-9

2015

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The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

eLife, 2015-03, Vol.4

2015

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Synthesis, function, and regulation of sterol and nonsterol isoprenoids

Frontiers in molecular biosciences, 2022-10, Vol.9, p.1006822-1006822

2022

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Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1

eLife, 2021-11, Vol.10

2021

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Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

Molecular biology of the cell, 2013-02, Vol.24 (3), p.169-183

2013

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Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency

eLife, 2020-03, Vol.9

2020

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Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20503-20508

2011

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Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

Critical reviews in biochemistry and molecular biology, 2010-06, Vol.45 (3), p.185-198

2010

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Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

The Journal of biological chemistry, 2011-04, Vol.286 (17), p.15022-15031

2011

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Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice

eLife, 2019-02, Vol.8

2019

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Multiple Signaling Pathways Regulating Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression: More Complicated than We Thought

Molecular endocrinology (Baltimore, Md.), 2005-11, Vol.19 (11), p.2647-2659

2005

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Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi[S]

Journal of lipid research, 2016-07, Vol.57 (7), p.1286-1299

2016

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Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells

Molecular biology of the cell, 2013-11, Vol.24 (21), p.3300-3308

2013

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Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling

Journal of endocrinology, 2007-04, Vol.193 (1), p.53-63

2007

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Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

Journal of lipid research, 2013-04, Vol.54 (4), p.1011-1022

2013

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cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation

Journal of molecular endocrinology, 2006-08, Vol.37 (1), p.81-95

2006

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Molecular Mechanisms of Insulin-like Growth Factor-I Mediated Regulation of the Steroidogenic Acute Regulatory Protein in Mouse Leydig Cells

Molecular endocrinology (Baltimore, Md.), 2006-02, Vol.20 (2), p.362-378

2006

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Regulation of Lipid Metabolism and Beyond

International Journal of Endocrinology, 2016-01, Vol.2016, p.5415767-2

2016

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Complex Role of the Mitochondrial Targeting Signal in the Function of Steroidogenic Acute Regulatory Protein Revealed by Bacterial Artificial Chromosome Transgenesis in Vivo

Molecular endocrinology (Baltimore, Md.), 2008-04, Vol.22 (4), p.951-964

2008

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Post-Translational Regulation of HMG CoA Reductase

Cold Spring Harbor perspectives in biology, 2022-12, Vol.14 (12)

2022

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Regulation of Steroidogenesis and Steroidogenic Acute Regulatory Protein in R2C Cells by DAX-1 (Dosage-Sensitive Sex Reversal, Adrenal Hypoplasia Congenita, Critical Region on the X Chromosome, Gene-1)

Endocrinology (Philadelphia), 2004-12, Vol.145 (12), p.5629-5637

2004

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The Vitamin K2Synthetic Enzyme UBIAD1 Moonlights as a Key Regulator of Cholesterol Synthesis

The FASEB journal, 2022-05, Vol.36, p.n/a

2022

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Inhibition of Cyclooxygenase-2 Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells

Endocrinology (Philadelphia), 2003-08, Vol.144 (8), p.3368-3375

2003

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Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol

Role of FTO in Adipocyte Development and Function: Recent Insights

Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

Synthesis, function, and regulation of sterol and nonsterol isoprenoids

Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes

Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice

Multiple Signaling Pathways Regulating Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression: More Complicated than We Thought

Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi[S]

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells

Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling

Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells

cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation

Molecular Mechanisms of Insulin-like Growth Factor-I Mediated Regulation of the Steroidogenic Acute Regulatory Protein in Mouse Leydig Cells

Regulation of Lipid Metabolism and Beyond

Complex Role of the Mitochondrial Targeting Signal in the Function of Steroidogenic Acute Regulatory Protein Revealed by Bacterial Artificial Chromosome Transgenesis in Vivo

Post-Translational Regulation of HMG CoA Reductase

Regulation of Steroidogenesis and Steroidogenic Acute Regulatory Protein in R2C Cells by DAX-1 (Dosage-Sensitive Sex Reversal, Adrenal Hypoplasia Congenita, Critical Region on the X Chromosome, Gene-1)

The Vitamin K2Synthetic Enzyme UBIAD1 Moonlights as a Key Regulator of Cholesterol Synthesis

Inhibition of Cyclooxygenase-2 Activity Enhances Steroidogenesis and Steroidogenic Acute Regulatory Gene Expression in MA-10 Mouse Leydig Cells

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