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Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer

Frontiers in oncology, 2017-11, Vol.7, p.286-286

2017

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Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (43), p.E9066-E9075

2017

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Mitochondrial Diseases Part I: mouse models of OXPHOS deficiencies caused by defects in respiratory complex subunits or assembly factors

Mitochondrion, 2015-03, Vol.21, p.76-91

2015

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Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer

Scientific reports, 2022-05, Vol.12 (1), p.8020-8020, Article 8020

2022

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Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses

Nature communications, 2019-02, Vol.10 (1), p.903-903, Article 903

2019

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New Insights on Rotenone Resistance of Complex I Induced by the m.11778G>A/ MT-ND4 Mutation Associated with Leber's Hereditary Optic Neuropathy

Molecules (Basel, Switzerland), 2022-02, Vol.27 (4), p.1341

2022

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Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes

The international journal of biochemistry & cell biology, 2013-01, Vol.45 (1), p.47-63

2013

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NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate

Cell reports (Cambridge), 2021-04, Vol.35 (3), p.109002-109002, Article 109002

2021

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Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer

International journal of cancer, 2018-10, Vol.143 (7), p.1706-1719

2018

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Haplogroup J mitogenomes are the most sensitive to the pesticide rotenone: Relevance for human diseases

Neurobiology of disease, 2018-06, Vol.114, p.129-139

2018

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Lithium and Not Acetoacetate Influences the Growth of Cells Treated with Lithium Acetoacetate

International journal of molecular sciences, 2019-06, Vol.20 (12), p.3104

2019

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Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.9001-9006

2007

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NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors

Open biology, 2022-11, Vol.12 (11), p.220198

2022

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The Oncojanus Paradigm of Respiratory Complex I

Genes, 2018-05, Vol.9 (5), p.243

2018

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Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization

International journal of molecular sciences, 2018-03, Vol.19 (3), p.764

2018

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The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes

Human molecular genetics, 2013-06, Vol.22 (11), p.2141-2151

2013

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The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity

PloS one, 2009-11, Vol.4 (11), p.e7922-e7922

2009

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Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome

Cells (Basel, Switzerland), 2021-10, Vol.10 (11), p.2920

2021

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Mitochondrial metabolism and energy sensing in tumor progression

Biochimica et biophysica acta. Bioenergetics, 2017-08, Vol.1858 (8), p.582-590

2017

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The multifaceted contribution of α-ketoglutarate to tumor progression: An opportunity to exploit?

Seminars in cell & developmental biology, 2020-02, Vol.98, p.26-33

2020

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Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer

Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer

Mitochondrial Diseases Part I: mouse models of OXPHOS deficiencies caused by defects in respiratory complex subunits or assembly factors

Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses

New Insights on Rotenone Resistance of Complex I Induced by the m.11778G>A/ MT-ND4 Mutation Associated with Leber's Hereditary Optic Neuropathy

Complex I impairment in mitochondrial diseases and cancer: Parallel roads leading to different outcomes

Peculiar combinations of individually non-pathogenic missense mitochondrial DNA variants cause low penetrance Leber's hereditary optic neuropathy

NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate

Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer

Haplogroup J mitogenomes are the most sensitive to the pesticide rotenone: Relevance for human diseases

Lithium and Not Acetoacetate Influences the Growth of Cells Treated with Lithium Acetoacetate

Mice harbouring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity

Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors

NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors

The Oncojanus Paradigm of Respiratory Complex I

Rare primary mitochondrial DNA mutations and probable synergistic variants in Leber's hereditary optic neuropathy

Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization

The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes

The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity

Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome

MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer

Mitochondrial metabolism and energy sensing in tumor progression

Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

The multifaceted contribution of α-ketoglutarate to tumor progression: An opportunity to exploit?

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