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Human genetics of Type 2 Diabetes and Its Clinical Implications

Journal of the Japan Diabetes Society, 2022/04/30, Vol.65(4), pp.179-182

Imamura, Minako

2022

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Genetics of type 2 diabetes: the GWAS era and future perspectives [Review]

Endocrine Journal, 2011, Vol.58(9), pp.723-739

2011

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Perspectives on genetic studies of type 2 diabetes from the genome‐wide association studies era to precision medicine

Journal of diabetes investigation, 2024-04, Vol.15 (4), p.410-422

2024

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Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin

Endocrinology (Philadelphia), 2015-06, Vol.156 (6), p.1982-1994

2015

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Susceptible Genes for Diabetic Retinopathy

Journal of the Japan Diabetes Society, 2019/11/30, Vol.62(11), pp.702-706

2019

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Profile of gut microbiota and serum metabolites associated with metabolic syndrome in a remote island most afflicted by obesity in Japan

Scientific reports, 2022-10, Vol.12 (1), p.17292-17292, Article 17292

2022

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A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes

PloS one, 2018-12, Vol.13 (12), p.e0208654-e0208654

2018

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Impact of anti-diabetic sodium-glucose cotransporter 2 inhibitors on tumor growth of intractable hematological malignancy in humans

Biomedicine & pharmacotherapy, 2022-05, Vol.149, p.112864-112864, Article 112864

2022

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Glucose-Dependent Transcriptional Regulation by an Evolutionarily Conserved Glucose-Sensing Module

Diabetes (New York, N.Y.), 2006-05, Vol.55 (5), p.1179-1189

2006

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Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)

Biochemical and biophysical research communications, 2010-05, Vol.395 (3), p.395-400

2010

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Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population

PloS one, 2013-09, Vol.8 (9), p.e76317-e76317

2013

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Assessing the Clinical Utility of a Genetic Risk Score Constructed Using 49 Susceptibility Alleles for Type 2 Diabetes in a Japanese Population

The journal of clinical endocrinology and metabolism, 2013-10, Vol.98 (10), p.E1667-E1673

2013

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Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies

PloS one, 2016-04, Vol.11 (4), p.e0154093-e0154093

2016

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Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes

PloS one, 2015-05, Vol.10 (5), p.e0126363-e0126363

2015

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A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population

PloS one, 2012-09, Vol.7 (9), p.e46263-e46263

2012

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ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts

American journal of physiology: endocrinology and metabolism, 2002-10, Vol.283 (4), p.E775-E783

2002

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The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes

PloS one, 2013-01, Vol.8 (1), p.e54064-e54064

2013

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Accumulation of 8-Hydroxy-2′-Deoxyguanosine and Mitochondrial DNA Deletion in Kidney of Diabetic Rats

Diabetes (New York, N.Y.), 2002-05, Vol.51 (5), p.1588-1595

2002

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Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population

Journal of human genetics, 2013-07, Vol.58 (7), p.490-493

2013

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Adenovirus-Mediated High Expression of Resistin Causes Dyslipidemia in Mice

Endocrinology (Philadelphia), 2005-01, Vol.146 (1), p.273-279

2005

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Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes

Clinical and experimental nephrology, 2013-12, Vol.17 (6), p.866-871

2013

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Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago

Molecular biology and evolution, 2021-05, Vol.38 (5), p.2045-2056

2021

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Expression of Adipose Differentiation-Related Protein (ADRP) Is Conjointly Regulated by PU.1 and AP-1 in Macrophages

Journal of biochemistry (Tokyo), 2005-10, Vol.138 (4), p.399-412

2005

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Replication study of the association of rs7578597 in THADA, rs10886471 in GRK5, and rs7403531 in RASGRP1 with susceptibility to type 2 diabetes among a Japanese population

Diabetology international, 2015-12, Vol.6 (4), p.306-312

2015

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Human genetics of Type 2 Diabetes and Its Clinical Implications

Genetics of type 2 diabetes: the GWAS era and future perspectives [Review]

Perspectives on genetic studies of type 2 diabetes from the genome‐wide association studies era to precision medicine

Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin

Genome-wide association study identifies three novel loci for type 2 diabetes

Susceptible Genes for Diabetic Retinopathy

Profile of gut microbiota and serum metabolites associated with metabolic syndrome in a remote island most afflicted by obesity in Japan

A variant within the FTO confers susceptibility to diabetic nephropathy in Japanese patients with type 2 diabetes

Impact of anti-diabetic sodium-glucose cotransporter 2 inhibitors on tumor growth of intractable hematological malignancy in humans

Glucose-Dependent Transcriptional Regulation by an Evolutionarily Conserved Glucose-Sensing Module

Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)

Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population

Assessing the Clinical Utility of a Genetic Risk Score Constructed Using 49 Susceptibility Alleles for Type 2 Diabetes in a Japanese Population

Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies

Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes

A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population

ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts

The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes

Accumulation of 8-Hydroxy-2′-Deoxyguanosine and Mitochondrial DNA Deletion in Kidney of Diabetic Rats

Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population

Adenovirus-Mediated High Expression of Resistin Causes Dyslipidemia in Mice

Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes

Fine-Scale Genetic Structure and Demographic History in the Miyako Islands of the Ryukyu Archipelago

Expression of Adipose Differentiation-Related Protein (ADRP) Is Conjointly Regulated by PU.1 and AP-1 in Macrophages

Replication study of the association of rs7578597 in THADA, rs10886471 in GRK5, and rs7403531 in RASGRP1 with susceptibility to type 2 diabetes among a Japanese population

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