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Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy

Angewandte Chemie (International ed.), 2016-03, Vol.55 (14), p.4497-4499

International ed. in English, 2016

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A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs

Angewandte Chemie (International ed.), 2018-07, Vol.57 (28), p.8458-8462

International ed. in English, 2018

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Cytochrome‐P450‐Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs

Angewandte Chemie (International ed.), 2018-03, Vol.57 (13), p.3391-3395

International ed. in English, 2018

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Structure and Function of an NADPH-Cytochrome P450 Oxidoreductase in an Open Conformation Capable of Reducing Cytochrome P450

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11374-11384

2009

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A Model of the Membrane-bound Cytochrome b5-Cytochrome P450 Complex from NMR and Mutagenesis Data

The Journal of biological chemistry, 2013-07, Vol.288 (30), p.22080-22095

2013

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Probing the Transmembrane Structure and Dynamics of Microsomal NADPH-cytochrome P450 oxidoreductase by Solid-State NMR

Biophysical journal, 2014-05, Vol.106 (10), p.2126-2133

2014

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Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases

Endocrinology (Philadelphia), 2020-08, Vol.161 (8)

2020

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Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles

Scientific reports, 2013-08, Vol.3 (1), p.2556-2556, Article 2556

2013

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Substrate mediated redox partner selectivity of cytochrome P450

Chemical communications (Cambridge, England), 2018, Vol.54 (45), p.5780-5783

2018

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Lipid-exchange in nanodiscs discloses membrane boundaries of cytochrome-P450 reductase

Chemical communications (Cambridge, England), 2018-06, Vol.54 (49), p.6336-6339

2018

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Cytochrome b5 Increases the Rate of Product Formation by Cytochrome P450 2B4 and Competes with Cytochrome P450 Reductase for a Binding Site on Cytochrome P450 2B4

The Journal of biological chemistry, 2007-10, Vol.282 (41), p.29766-29776

2007

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Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding

The Journal of biological chemistry, 2011-05, Vol.286 (18), p.16246-16260

2011

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Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy

Scientific reports, 2013-08, Vol.3 (1), p.2538, Article 2538

2013

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The interaction of microsomal cytochrome P450 2B4 with its redox partners, cytochrome P450 reductase and cytochrome b5

Archives of biochemistry and biophysics, 2011-03, Vol.507 (1), p.144-153

2011

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Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c

Scientific reports, 2017-08, Vol.7 (1), p.7793-15, Article 7793

2017

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Temperature-Resistant Bicelles for Structural Studies by Solid-State NMR Spectroscopy

Langmuir, 2015-02, Vol.31 (4), p.1496-1504

2015

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Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs

Chemical communications (Cambridge, England), 2018-08, Vol.54 (69), p.9615-9618

2018

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Distinct conformational behaviors of four mammalian dual‐flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles

The FEBS journal, 2014-12, Vol.281 (23), p.5325-5340

2014

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Bicelle-Enabled Structural Studies on a Membrane-Associated Cytochrome b₅ by Solid-State MAS NMR Spectroscopy

Angewandte Chemie (International ed.), 2008-09, Vol.47 (41), p.7864-7867

2008

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Non-Ionic Inulin-Based Polymer Nanodiscs Enable Functional Reconstitution of a Redox Complex Composed of Oppositely Charged CYP450 and CPR in a Lipid Bilayer Membrane

Analytical chemistry (Washington), 2022-08, Vol.94 (34), p.11908-11915

2022

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Cytochrome b5 Inhibits Electron Transfer from NADPH-Cytochrome P450 Reductase to Ferric Cytochrome P450 2B4

The Journal of biological chemistry, 2008-02, Vol.283 (9), p.5217-5225

2008

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Influence of cholesterol on kinetic parameters for human aromatase (P450 19A1) in phospholipid nanodiscs

Journal of inorganic biochemistry, 2023-10, Vol.247, p.112340-112340, Article 112340

2023

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Cellular solid-state NMR investigation of a membrane protein using dynamic nuclear polarization

Biochimica et biophysica acta, 2015-01, Vol.1848 (1), p.342-349

2015

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Solid-State NMR Reveals Structural and Dynamical Properties of a Membrane-Anchored Electron-Carrier Protein, Cytochrome b5

Journal of the American Chemical Society, 2007-05, Vol.129 (21), p.6670-6671

2007

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Kinetics of Intermediate Release Enhances P450 11B2-Catalyzed Aldosterone Synthesis

Biochemistry (Easton), 2024-04, Vol.63 (8), p.1026-1037

2024

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Reconstitution of the Cytb5-CytP450 Complex in Nanodiscs for Structural Studies using NMR Spectroscopy

A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs

Cytochrome‐P450‐Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs

Structure and Function of an NADPH-Cytochrome P450 Oxidoreductase in an Open Conformation Capable of Reducing Cytochrome P450

A Model of the Membrane-bound Cytochrome b5-Cytochrome P450 Complex from NMR and Mutagenesis Data

Probing the Transmembrane Structure and Dynamics of Microsomal NADPH-cytochrome P450 oxidoreductase by Solid-State NMR

Expression in Escherichia Coli, Purification, and Functional Reconstitution of Human Steroid 5α-Reductases

Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles

Substrate mediated redox partner selectivity of cytochrome P450

Lipid-exchange in nanodiscs discloses membrane boundaries of cytochrome-P450 reductase

Cytochrome b5 Increases the Rate of Product Formation by Cytochrome P450 2B4 and Competes with Cytochrome P450 Reductase for a Binding Site on Cytochrome P450 2B4

Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding

Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy

The interaction of microsomal cytochrome P450 2B4 with its redox partners, cytochrome P450 reductase and cytochrome b5

Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c

Temperature-Resistant Bicelles for Structural Studies by Solid-State NMR Spectroscopy

Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs

Distinct conformational behaviors of four mammalian dual‐flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles

Bicelle-Enabled Structural Studies on a Membrane-Associated Cytochrome b₅ by Solid-State MAS NMR Spectroscopy

Non-Ionic Inulin-Based Polymer Nanodiscs Enable Functional Reconstitution of a Redox Complex Composed of Oppositely Charged CYP450 and CPR in a Lipid Bilayer Membrane

Cytochrome b5 Inhibits Electron Transfer from NADPH-Cytochrome P450 Reductase to Ferric Cytochrome P450 2B4

Influence of cholesterol on kinetic parameters for human aromatase (P450 19A1) in phospholipid nanodiscs

Cellular solid-state NMR investigation of a membrane protein using dynamic nuclear polarization

Solid-State NMR Reveals Structural and Dynamical Properties of a Membrane-Anchored Electron-Carrier Protein, Cytochrome b5

Kinetics of Intermediate Release Enhances P450 11B2-Catalyzed Aldosterone Synthesis

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