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Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

Clinical science (1979), 2017-10, Vol.131 (19), p.2451

2017

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Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment

Journal of neuroinflammation, 2020-12, Vol.17 (1), p.367-367, Article 367

2020

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Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators

Journal of cerebral blood flow and metabolism, 2018-08, Vol.38 (8), p.1354-1370

2018

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Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

Scientific reports, 2018-08, Vol.8 (1), p.12552-14, Article 12552

2018

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The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

Neuron (Cambridge, Mass.), 2012-05, Vol.74 (3), p.543-556

2012

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Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (1), p.E1-E2

2011

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Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

Glia, 2018-01, Vol.66 (1), p.34-46

2018

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Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion

Journal of neuroinflammation, 2017-04, Vol.14 (1), p.81-81, Article 81

2017

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Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

Scientific reports, 2017-06, Vol.7 (1), p.4299-11, Article 4299

2017

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The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

Journal of cerebral blood flow and metabolism, 2018-01, Vol.38 (1), p.151-165

2018

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4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

Human molecular genetics, 2019-02, Vol.28 (4), p.628-638

2019

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Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion

The Journal of neuroscience, 2011-12, Vol.31 (49), p.18185-18194

2011

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Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment

Brain research bulletin, 2020-10, Vol.163, p.72-83

2020

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Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory

Journal of cerebral blood flow and metabolism, 2016-09, Vol.36 (9), p.1592-1602

2016

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Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment

Frontiers in aging neuroscience, 2022-01, Vol.13, p.788519-788519

2022

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Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion

Acta neuropathologica communications, 2024-02, Vol.12 (1), p.29-29

2024

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Selective white matter pathology induces a specific impairment in spatial working memory

Neurobiology of aging, 2011-12, Vol.32 (12), p.2324.e7-2324.e12

2011

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Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

PloS one, 2014-02, Vol.9 (2), p.e87227-e87227

2014

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Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice

PloS one, 2014-02, Vol.9 (2), p.e89970-e89970

2014

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Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

The European journal of neuroscience, 2007-03, Vol.25 (6), p.1832-1842

2007

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Proteomic Analysis of Mitochondria in APOE Transgenic Mice and in Response to an Ischemic Challenge

Journal of cerebral blood flow and metabolism, 2012-01, Vol.32 (1), p.164-176

2012

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White matter degeneration in vascular and other ageing‐related dementias

Journal of neurochemistry, 2018-03, Vol.144 (5), p.617-633

2018

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Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

Brain research, 2004-01, Vol.997 (1), p.15-23

2004

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Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse

American journal of translational research, 2012-01, Vol.4 (2), p.151-164

2012

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Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease

American journal of translational research, 2011-02, Vol.3 (2), p.197-208

2011

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Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment

Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators

Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion

Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion

Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment

Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory

Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment

Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion

Selective white matter pathology induces a specific impairment in spatial working memory

Restoration of oligodendrocyte pools in a mouse model of chronic cerebral hypoperfusion

Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice

Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia

Proteomic Analysis of Mitochondria in APOE Transgenic Mice and in Response to an Ischemic Challenge

White matter degeneration in vascular and other ageing‐related dementias

Extension of cerebral hypoperfusion and ischaemic pathology beyond MCA territory after intraluminal filament occlusion in C57Bl/6J mice

Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse

Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease

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