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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Nature reviews. Endocrinology, 2016-11, Vol.12 (11), p.633

2016

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Cell metabolism, 2011-11, Vol.14 (5), p.612-622

2011

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Exercising your fat (metabolism) into shape: a muscle-centred view

Diabetologia, 2020-08, Vol.63 (8), p.1453-1463

2020

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Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes

Diabetologia, 2017-03, Vol.60 (3), p.490-498

2017

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Effects of exercise training on intrahepatic lipid content in humans

Diabetologia, 2016-10, Vol.59 (10), p.2068-2079

2016

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Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

Annals of the New York Academy of Sciences, 2013-07, Vol.1290 (1), p.83-89

2013

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Elevated Plasma Branched-Chain Amino Acid Levels Correlate With Type 2 Diabetes–Related Metabolic Disturbances

The journal of clinical endocrinology and metabolism, 2021-04, Vol.106 (4), p.e1827-e1836

2021

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Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.572-579

2010

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794

2018

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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Diabetes (New York, N.Y.), 2008-11, Vol.57 (11), p.2943-2949

2008

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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Diabetologia, 2021-02, Vol.64 (2), p.424-436

2021

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Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

Nature medicine, 2015-08, Vol.21 (8), p.863

2015

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Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Nature medicine, 2013-08, Vol.19 (8), p.1039

2013

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Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2679-2690

2012

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Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial

Diabetes care, 2016-12, Vol.39 (12), p.2211-2217

2016

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Nature communications, 2022-06, Vol.13 (1), p.3508-3508, Article 3508

2022

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Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

Diabetes (New York, N.Y.), 2010-09, Vol.59 (9), p.2117-2125

2010

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Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes

Diabetes (New York, N.Y.), 2004-06, Vol.53 (6), p.1412-1417

2004

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ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

eLife, 2015-10, Vol.4

2015

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Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

The journal of clinical endocrinology and metabolism, 2013-04, Vol.98 (4), p.1694-1702

2013

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Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Trends in molecular medicine, 2021-11, Vol.27 (11), p.1033-1044

2021

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Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial

Diabetes care, 2021-06, Vol.44 (6), p.1334-1343

2021

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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4915-4925

2014

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Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes

Clinical science (1979), 2017-08, Vol.131 (15), p.1905

2017

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Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

Diabetes (New York, N.Y.), 2015-04, Vol.64 (4), p.1193-1201

2015

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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Exercising your fat (metabolism) into shape: a muscle-centred view

Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes

Effects of exercise training on intrahepatic lipid content in humans

Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

Elevated Plasma Branched-Chain Amino Acid Levels Correlate With Type 2 Diabetes–Related Metabolic Disturbances

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial

A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial

Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

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