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Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis

PLoS biology, 2020-12, Vol.18 (12), p.e3001032-e3001032

2020

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Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis

Cell reports (Cambridge), 2016-05, Vol.15 (5), p.911-918

2016

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A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion

EMBO reports, 2011-11, Vol.12 (11), p.1144-1152

2011

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Wnt Ligands as a Part of the Stem Cell Niche in the Intestine and the Liver

Progress in molecular biology and translational science, 2018-01, Vol.153, p.1-19

2018

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Wingless secretion promotes and requires retromer-dependent cycling of Wntless

Nature cell biology, 2008-02, Vol.10 (2), p.178-185

2008

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The hedgehog signaling pathway: where did it come from?

PLoS biology, 2009-06, Vol.7 (6), p.e1000146-e1000146

2009

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Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells

Nature communications, 2021-03, Vol.12 (1), p.1368-1368, Article 1368

2021

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The many faces and functions of β-catenin

The EMBO journal, 2012-06, Vol.31 (12), p.2714-2736

2012

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The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription

Development (Cambridge), 2013-06, Vol.140 (11), p.2377-2386

2013

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GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells

Nature (London), 2018-06, Vol.558 (7710), p.449-453

2018

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β-Catenin hits chromatin: regulation of Wnt target gene activation

Nature reviews. Molecular cell biology, 2009-04, Vol.10 (4), p.276-286

2009

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Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model

iScience, 2021-12, Vol.24 (12), p.103369-103369, Article 103369

2021

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WNT secretion and signalling in human disease

Trends in molecular medicine, 2012-08, Vol.18 (8), p.483-493

2012

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Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein–protein interfaces of nuclear factors

British journal of pharmacology, 2017-12, Vol.174 (24), p.4600-4610

2017

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The Conserved SOCS Box Motif in Suppressors of Cytokine Signaling Binds to Elongins B and C and May Couple Bound Proteins to Proteasomal Degradation

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (5), p.2071-2076

1999

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Parafibromin/Hyrax Activates Wnt/Wg Target Gene Transcription by Direct Association with β-catenin/Armadillo

Cell, 2006-04, Vol.125 (2), p.327-341

2006

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Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells

Cell, 2006-05, Vol.125 (3), p.509-522

2006

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Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage

Cell reports (Cambridge), 2021-08, Vol.36 (5), p.109484-109484, Article 109484

2021

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Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (34), p.1

2021

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A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation

Science signaling, 2017-02, Vol.10 (465)

2017

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Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members

EMBO reports, 2023-09, Vol.24 (9), p.e56454-e56454

2023

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Helping Wingless take flight: how WNT proteins are secreted

Nature reviews. Molecular cell biology, 2007-04, Vol.8 (4), p.331-336

2007

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Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

Genes & development, 2014-09, Vol.28 (17), p.1879-1884

2014

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WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma

Oncogene, 2018-07, Vol.37 (27), p.3753-3762

2018

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Cryo-EM structure of the Hedgehog release protein Dispatched

Science advances, 2020-04, Vol.6 (16), p.eaay7928-eaay7928

2020

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Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis

Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis

A genome-wide RNA interference screen uncovers two p24 proteins as regulators of Wingless secretion

Wnt Ligands as a Part of the Stem Cell Niche in the Intestine and the Liver

Wingless secretion promotes and requires retromer-dependent cycling of Wntless

The hedgehog signaling pathway: where did it come from?

Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells

The many faces and functions of β-catenin

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription

GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells

β-Catenin hits chromatin: regulation of Wnt target gene activation

Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model

WNT secretion and signalling in human disease

Pharmacological interventions in the Wnt pathway: inhibition of Wnt secretion versus disrupting the protein–protein interfaces of nuclear factors

The Conserved SOCS Box Motif in Suppressors of Cytokine Signaling Binds to Elongins B and C and May Couple Bound Proteins to Proteasomal Degradation

Parafibromin/Hyrax Activates Wnt/Wg Target Gene Transcription by Direct Association with β-catenin/Armadillo

Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells

Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage

Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation

Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members

Helping Wingless take flight: how WNT proteins are secreted

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma

Cryo-EM structure of the Hedgehog release protein Dispatched

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