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Recent Advances in Endogenous and Exogenous Stimuli-Responsive Nanocarriers for Drug Delivery and Therapeutics

Chemical and Pharmaceutical Bulletin, 2017/07/01, Vol.65(7), pp.612-617

Hatakeyama, Hiroto

2017

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The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

Biological and Pharmaceutical Bulletin, 2013/06/01, Vol.36(6), pp.892-899

2013

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Recent Advances in Endogenous and Exogenous Stimuli-Responsive Nanocarriers for Drug Delivery and Therapeutics

Chemical and Pharmaceutical Bulletin, 2017-07, Vol.65 (7), p.612-617

Hiroto Hatakeyama

2017

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A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

Journal of controlled release, 2012-11, Vol.163 (3), p.267-276

2012

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Investigation of Metabolomic Changes in Sunitinib-Resistant Human Renal Carcinoma 786-O Cells by Capillary Electrophoresis-Time of Flight Mass Spectrometry

Biological and Pharmaceutical Bulletin, 2018/04/01, Vol.41(4), pp.619-627

2018

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Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system

Archives of Pharmacal Research, 2014, 37(1), , pp.4-15

2014

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Dual-ligand modification of PEGylated liposomes shows better cell selectivity and efficient gene delivery

Journal of controlled release, 2011-07, Vol.153 (2), p.141-148

2011

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Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress

Scientific reports, 2021-07, Vol.11 (1), p.14726-14726, Article 14726

2021

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Comparative Study of the Sensitivities of Cancer Cells to Doxorubicin, and Relationships between the Effect of the Drug-Efflux Pump P-gp

Biological and Pharmaceutical Bulletin, 2014/12/01, Vol.37(12), pp.1926-1935

2014

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Combined nano cancer immunotherapy based on immune status in a tumor microenvironment

Journal of controlled release, 2022-05, Vol.345, p.200-213

2022

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Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Cancer science, 2022-05, Vol.113 (5), p.1855-1867

2022

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Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines

Biological and Pharmaceutical Bulletin, 2024/03/26, Vol.47(3), pp.698-707

2024

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HSP70 Inhibition Synergistically Enhances the Effects of Magnetic Fluid Hyperthermia in Ovarian Cancer

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.966-976

2017

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RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system

Journal of controlled release, 2014-01, Vol.173, p.110-118

2014

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The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice

Journal of controlled release, 2014-01, Vol.173, p.43-50

2014

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Effects of ceramide kinase knockout on lipopolysaccharide-treated sepsis-model mice: Changes in serum cytokine/chemokine levels and increased lethality

Journal of pharmacological sciences, 2022-09, Vol.150 (1), p.1-8

2022

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Advances in an active and passive targeting to tumor and adipose tissues

Expert opinion on drug delivery, 2015-01, Vol.12 (1), p.41-52

2015

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Trichostatin A modulates cellular metabolism in renal cell carcinoma to enhance sunitinib sensitivity

European journal of pharmacology, 2019-03, Vol.847, p.143-157

2019

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Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas

Molecular pharmaceutics, 2014-08, Vol.11 (8), p.2713-2719

2014

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Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles

Advanced healthcare materials, 2023-04, Vol.12 (9), p.e2202528-n/a

2023

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Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA

Biomaterials, 2011-08, Vol.32 (24), p.5733-5742

2011

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Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors

Cancers, 2020-12, Vol.12 (12), p.3630

2020

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Size-dependent specific targeting and efficient gene silencing in peritoneal macrophages using a pH-sensitive cationic liposomal siRNA carrier

International journal of pharmaceutics, 2015-11, Vol.495 (1), p.171-178

2015

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Lipid Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery to the Pulmonary Endothelium

ACS nano, 2013-09, Vol.7 (9), p.7534-7541

2013

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An apolipoprotein E modified liposomal nanoparticle: Ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells

International journal of pharmaceutics, 2014-04, Vol.465 (1-2), p.77-82

2014

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Recent Advances in Endogenous and Exogenous Stimuli-Responsive Nanocarriers for Drug Delivery and Therapeutics

The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

Recent Advances in Endogenous and Exogenous Stimuli-Responsive Nanocarriers for Drug Delivery and Therapeutics

A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo

Investigation of Metabolomic Changes in Sunitinib-Resistant Human Renal Carcinoma 786-O Cells by Capillary Electrophoresis-Time of Flight Mass Spectrometry

Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system

Dual-ligand modification of PEGylated liposomes shows better cell selectivity and efficient gene delivery

Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress

Comparative Study of the Sensitivities of Cancer Cells to Doxorubicin, and Relationships between the Effect of the Drug-Efflux Pump P-gp

Combined nano cancer immunotherapy based on immune status in a tumor microenvironment

Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell‐specific liposomal siRNA delivery system

Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines

HSP70 Inhibition Synergistically Enhances the Effects of Magnetic Fluid Hyperthermia in Ovarian Cancer

RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system

The systemic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice

Effects of ceramide kinase knockout on lipopolysaccharide-treated sepsis-model mice: Changes in serum cytokine/chemokine levels and increased lethality

Advances in an active and passive targeting to tumor and adipose tissues

Trichostatin A modulates cellular metabolism in renal cell carcinoma to enhance sunitinib sensitivity

Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas

Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles

Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA

Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors

Size-dependent specific targeting and efficient gene silencing in peritoneal macrophages using a pH-sensitive cationic liposomal siRNA carrier

Lipid Envelope-Type Nanoparticle Incorporating a Multifunctional Peptide for Systemic siRNA Delivery to the Pulmonary Endothelium

An apolipoprotein E modified liposomal nanoparticle: Ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells

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