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Making waves: A proposed new role for myosin-binding protein C in regulating oscillatory contractions in vertebrate striated muscle

The Journal of general physiology, 2021-03, Vol.153 (3), p.1

Harris, Samantha P

2021

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A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

PloS one, 2016-12, Vol.11 (12), p.e0168407

2016

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MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy

PloS one, 2017-06, Vol.12 (6), p.e0180064-e0180064

2017

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The Myosin-binding Protein C Motif Binds to F-actin in a Phosphorylation-sensitive Manner

The Journal of biological chemistry, 2009-05, Vol.284 (18), p.12318-12327

2009

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N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament

Structure (London), 2018-12, Vol.26 (12), p.1604-1611.e4

2018

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Effects of Cardiac Myosin Binding Protein-C on Actin Motility Are Explained with a Drag-Activation-Competition Model

Biophysical journal, 2015-01, Vol.108 (1), p.10-13

2015

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An Anatomic Investigation of the Mandibular First Molar Using Micro–Computed Tomography

Journal of endodontics, 2013-11, Vol.39 (11), p.1374-1378

2013

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A Novel “Cut and Paste” Method for In Situ Replacement of cMyBP-C Reveals a New Role for cMyBP-C in the Regulation of Contractile Oscillations

Circulation research, 2020-03, Vol.126 (6), p.737-749

2020

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Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

Scientific reports, 2023-01, Vol.13 (1), p.32-11, Article 32

2023

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Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads

Nature communications, 2024-03, Vol.15 (1), p.2628-2628

2024

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Ambulatory electrocardiography, heart rate variability, and pharmacologic stress testing in cats with subclinical hypertrophic cardiomyopathy

Scientific reports, 2022-02, Vol.12 (1), p.1963-1963, Article 1963

2022

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Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C

Scientific reports, 2023-06, Vol.13 (1), p.10319-10319, Article 10319

2023

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C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (6), p.1558-1563

2016

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Myosin binding protein-C: Everything, everywhere, all at once

Biophysical journal, 2023-02, Vol.122 (3), p.7a-7a

Harris, Samantha P.

2023

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Synergistic inhibitory effects of clopidogrel and rivaroxaban on platelet function and platelet‐dependent thrombin generation in cats

Journal of veterinary internal medicine, 2023-07, Vol.37 (4), p.1390-1400

2023

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Cardiac Myosin-Binding Protein C Decorates F-Actin: Implications for Cardiac Function

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18360-18365

2008

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The genetic basis of hypertrophic cardiomyopathy in cats and humans

Journal of veterinary cardiology, 2015-12, Vol.17 (Suppl 1), p.S53-S73

2015

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Mechanical Unfolding of Cardiac Myosin Binding Protein-C by Atomic Force Microscopy

Biophysical journal, 2011-10, Vol.101 (8), p.1968-1977

2011

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Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A Pilot Study

Animals (Basel), 2023-10, Vol.13 (20), p.3184

2023

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Cross-Species Mechanical Fingerprinting of Cardiac Myosin Binding Protein-C

Biophysical journal, 2013-06, Vol.104 (11), p.2465-2475

2013

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Cardiac Effects of a Single Dose of Pimobendan in Cats With Hypertrophic Cardiomyopathy; A Randomized, Placebo-Controlled, Crossover Study

Frontiers in veterinary science, 2019-02, Vol.6, p.15-15

2019

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Myofibril relaxation with mavacamten is modified by cMyBP-c

Biophysical journal, 2023-02, Vol.122 (3), p.402a-403a

2023

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Hypertrophic Cardiomyopathy in Cardiac Myosin Binding Protein-C Knockout Mice

Circulation research, 2002-03, Vol.90 (5), p.594-601

2002

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In the Thick of It: HCM-Causing Mutations in Myosin Binding Proteins of the Thick Filament

Circulation research, 2011-03, Vol.108 (6), p.751-764

2011

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Orientation of Myosin Binding Protein C in the Cardiac Muscle Sarcomere Determined by Domain-Specific Immuno-EM

Journal of molecular biology, 2015-01, Vol.427 (2), p.274-286

2015

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Making waves: A proposed new role for myosin-binding protein C in regulating oscillatory contractions in vertebrate striated muscle

A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy

The Myosin-binding Protein C Motif Binds to F-actin in a Phosphorylation-sensitive Manner

N-Terminal Domains of Cardiac Myosin Binding Protein C Cooperatively Activate the Thin Filament

Effects of Cardiac Myosin Binding Protein-C on Actin Motility Are Explained with a Drag-Activation-Competition Model

An Anatomic Investigation of the Mandibular First Molar Using Micro–Computed Tomography

A Novel “Cut and Paste” Method for In Situ Replacement of cMyBP-C Reveals a New Role for cMyBP-C in the Regulation of Contractile Oscillations

Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads

Ambulatory electrocardiography, heart rate variability, and pharmacologic stress testing in cats with subclinical hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C

C0 and C1 N-terminal Ig domains of myosin binding protein C exert different effects on thin filament activation

Myosin binding protein-C: Everything, everywhere, all at once

Synergistic inhibitory effects of clopidogrel and rivaroxaban on platelet function and platelet‐dependent thrombin generation in cats

Cardiac Myosin-Binding Protein C Decorates F-Actin: Implications for Cardiac Function

The genetic basis of hypertrophic cardiomyopathy in cats and humans

Mechanical Unfolding of Cardiac Myosin Binding Protein-C by Atomic Force Microscopy

Multi-Omic, Histopathologic, and Clinicopathologic Effects of Once-Weekly Oral Rapamycin in a Naturally Occurring Feline Model of Hypertrophic Cardiomyopathy: A Pilot Study

Cross-Species Mechanical Fingerprinting of Cardiac Myosin Binding Protein-C

Cardiac Effects of a Single Dose of Pimobendan in Cats With Hypertrophic Cardiomyopathy; A Randomized, Placebo-Controlled, Crossover Study

Myofibril relaxation with mavacamten is modified by cMyBP-c

Hypertrophic Cardiomyopathy in Cardiac Myosin Binding Protein-C Knockout Mice

In the Thick of It: HCM-Causing Mutations in Myosin Binding Proteins of the Thick Filament

Orientation of Myosin Binding Protein C in the Cardiac Muscle Sarcomere Determined by Domain-Specific Immuno-EM

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