UB Paderborn / Katalog / Suche / in CDI

Learn from failures and stay hopeful to GPR40, a GPCR target with robust efficacy, for therapy of metabolic disorders

Frontiers in pharmacology, 2022-10, Vol.13, p.1043828-1043828

2022

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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Science (American Association for the Advancement of Science), 2017-08, Vol.357 (6350), p.507-511

2017

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Glucagon receptor antagonism induces increased cholesterol absorption[S]

Journal of lipid research, 2015-11, Vol.56 (11), p.2183-2195

2015

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The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

PloS one, 2016-10, Vol.11 (10), p.e0164133-e0164133

2016

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A futile metabolic cycle activated in adipocytes by antidiabetic agents

Nature medicine, 2002-10, Vol.8 (10), p.1122-1128

2002

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Physiological Expression of AMPKγ2 Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice

The Journal of biological chemistry, , Vol.291 (45), p.23428-23439

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Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24644-24652

2009

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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

ACS medicinal chemistry letters, 2018-01, Vol.9 (1), p.39-44

2018

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Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Journal of lipid research, 2013-10, Vol.54 (10), p.2615-2622

2013

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Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

PloS one, 2017-01, Vol.12 (1), p.e0170721-e0170721

2017

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PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

American journal of physiology: endocrinology and metabolism, 2007-12, Vol.293 (6), p.E1736-E1745

2007

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Corepressors selectively control the transcriptional activity of PPARγ in adipocytes

Genes & development, 2005-02, Vol.19 (4), p.453-461

2005

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PPARγ regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

The Journal of clinical investigation, 2005-08, Vol.115 (8), p.2244-2256

2005

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Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα

Cell metabolism, 2005-05, Vol.1 (5), p.297-308

2005

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Factors Affecting Insulin-Regulated Hepatic Gene Expression

Progress in Molecular Biology and Translational Science, 2014, Vol.121, p.165-215

2014

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Reply to "A "futile cycle" induced by thiazolidinediones in human adipose tissue?"

Nature medicine, 2003-07, Vol.9 (7), p.812-812

2003

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Synphilin in normal human brains and in synucleinopathies: studies with new antibodies

Acta neuropathologica, 2003-02, Vol.105 (2), p.177-184

2003

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Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis

Hepatology (Baltimore, Md.), 2021-04, Vol.73 (4), p.1290-1306

2021

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Identification of a metabolic, transcriptomic and molecular signature of PNPLA3-mediated acceleration of steatohepatitis

Hepatology (Baltimore, Md.), 2020-11

2020

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Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice

The Journal of biological chemistry, 2016-11, Vol.291 (45), p.23428-23439

2016

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A rabbit model of pediatric nonalcoholic steatohepatitis： The role of adiponectin

World journal of gastroenterology : WJG, 2009-02, Vol.15 (8), p.912-918

2009

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PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

American journal of physiology: endocrinology and metabolism, 2007-12, Vol.293 (6), p.E1736-E1745

2007

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PPAR{gamma} regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

American journal of physiology: endocrinology and metabolism, 2007-12, Vol.293 (6), p.E1736

2007

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PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

American journal of physiology: endocrinology and metabolism, 2007, Vol.56 (6)

2007

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Learn from failures and stay hopeful to GPR40, a GPCR target with robust efficacy, for therapy of metabolic disorders

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Glucagon receptor antagonism induces increased cholesterol absorption[S]

The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

A futile metabolic cycle activated in adipocytes by antidiabetic agents

Physiological Expression of AMPKγ2 Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice

Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys

PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

Corepressors selectively control the transcriptional activity of PPARγ in adipocytes

PPARγ regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1

Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver

Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRα

Factors Affecting Insulin-Regulated Hepatic Gene Expression

Reply to "A "futile cycle" induced by thiazolidinediones in human adipose tissue?"

Synphilin in normal human brains and in synucleinopathies: studies with new antibodies

Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis

Identification of a metabolic, transcriptomic and molecular signature of PNPLA3-mediated acceleration of steatohepatitis

Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice

A rabbit model of pediatric nonalcoholic steatohepatitis： The role of adiponectin

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

PPAR{gamma} regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

PPARγ regulates adipose triglyceride lipase in adipocytes in vitro and in vivo

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