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Immunological Paradigms, Mechanisms, and Models: Conceptual Understanding Is a Prerequisite to Effective Modeling

Frontiers in immunology, 2019-11, Vol.10, p.2522-2522

Grossman, Zvi

2019

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Dynamic Tuning of Lymphocytes: Physiological Basis, Mechanisms, and Function

Annual review of immunology, 2015-03, Vol.33 (1), p.677-713

2015

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An integrative systems biology view of host-pathogen interactions: The regulation of immunity and homeostasis is concomitant, flexible, and smart

Frontiers in immunology, 2023-01, Vol.13, p.1061290-1061290

2023

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Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells

PLoS biology, 2011-10, Vol.9 (10), p.e1001171

2011

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HIV Infection Rapidly Induces and Maintains a Substantial Suppression of Thymocyte Proliferation

Immunity (Cambridge, Mass.), 2004-12, Vol.21 (6), p.757-768

2004

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Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3318-3323

2011

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Tuberculosis incidence in HIV/AIDS patients in Israel, 1983-2010

PloS one, 2013-11, Vol.8 (11), p.e79691-e79691

2013

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Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3312-3317

2011

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Altered thymic function during interferon therapy in HCV-infected patients

PloS one, 2012-04, Vol.7 (4), p.e34326

2012

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Relaxation of adaptive evolution during the HIV-1 infection owing to reduction of CD4+ T cell counts

PloS one, 2012-06, Vol.7 (6), p.e39776-e39776

2012

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Immune reconstitution in HIV infection: how to measure thymic function?

Clinical immunology (Orlando, Fla.), 2005-05, Vol.115 (2), p.115-117

Grossman, Zvi

2005

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Tuning of Activation Thresholds Explains Flexibility in the Selection and Development of T Cells in the Thymus

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14747-14752

1996

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High Production Rates Sustain In Vivo Levels of PD-1high Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance

Journal of Virology, 2013-09, Vol.87 (17), p.9836-9844

2013

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Tuberculosis Treatment in HIV Infected Ugandans with CD4 Counts >350 Cells/mm3 Reduces Immune Activation with No Effect on HIV Load or CD4 Count

PloS one, 2010-02, Vol.5 (2), p.e9138

2010

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Multiple Modes of Cellular Activation and Virus Transmission in HIV Infection: A Role for Chronically and Latently Infected Cells in Sustaining Viral Replication

Proceedings of the National Academy of Sciences - PNAS, 1998-05, Vol.95 (11), p.6314-6319

1998

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‘Rinse and Replace’: Boosting T Cell Turnover To Reduce HIV-1 Reservoirs

Trends in immunology, 2020-06, Vol.41 (6), p.466-480

2020

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Pathogenesis of HIV infection: what the virus spares is as important as what it destroys

Nature medicine, 2006-03, Vol.12 (3), p.289-295

2006

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Looking at HIV-infected lymph nodes

Blood, 2007-05, Vol.109 (10), p.4116-4117

Grossman, Zvi

2007

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Perspectives of (/memorandum for) systems thinking on COVID‐19 pandemic and pathology

Journal of evaluation in clinical practice, 2023-04, Vol.29 (3), p.415-429

2023

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HIV preferentially infects HIV-specific CD4 + T cells

Nature (London), 2002-05, Vol.417 (6884), p.95-98

2002

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Autoreactivity, dynamic tuning and selectivity

Current opinion in immunology, 2001-12, Vol.13 (6), p.687-698

2001

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HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

The Journal of experimental medicine, 2003-12, Vol.198 (12), p.1909-1922

2003

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Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

The Journal of experimental medicine, 2007-09, Vol.204 (9), p.2171-2185

2007

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CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load

The Journal of immunology (1950), 2002-09, Vol.169 (6), p.3400-3406

2002

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Immune activation, viral replication and mucosal depletion

Retrovirology, 2006-12, Vol.3 (Suppl 1), p.S72-S72, Article S72

Grossman, Zvi

2006

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Immunological Paradigms, Mechanisms, and Models: Conceptual Understanding Is a Prerequisite to Effective Modeling

Dynamic Tuning of Lymphocytes: Physiological Basis, Mechanisms, and Function

An integrative systems biology view of host-pathogen interactions: The regulation of immunity and homeostasis is concomitant, flexible, and smart

Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells

HIV Infection Rapidly Induces and Maintains a Substantial Suppression of Thymocyte Proliferation

Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number

Tuberculosis incidence in HIV/AIDS patients in Israel, 1983-2010

Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number

Altered thymic function during interferon therapy in HCV-infected patients

Relaxation of adaptive evolution during the HIV-1 infection owing to reduction of CD4+ T cell counts

Immune reconstitution in HIV infection: how to measure thymic function?

Tuning of Activation Thresholds Explains Flexibility in the Selection and Development of T Cells in the Thymus

High Production Rates Sustain In Vivo Levels of PD-1high Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance

Tuberculosis Treatment in HIV Infected Ugandans with CD4 Counts >350 Cells/mm3 Reduces Immune Activation with No Effect on HIV Load or CD4 Count

Multiple Modes of Cellular Activation and Virus Transmission in HIV Infection: A Role for Chronically and Latently Infected Cells in Sustaining Viral Replication

‘Rinse and Replace’: Boosting T Cell Turnover To Reduce HIV-1 Reservoirs

Pathogenesis of HIV infection: what the virus spares is as important as what it destroys

Looking at HIV-infected lymph nodes

Perspectives of (/memorandum for) systems thinking on COVID‐19 pandemic and pathology

HIV preferentially infects HIV-specific CD4 + T cells

Autoreactivity, dynamic tuning and selectivity

HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load

Immune activation, viral replication and mucosal depletion

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