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PML nuclear bodies: new players in familial amyotrophic lateral sclerosis-frontotemporal dementia?

Neural regeneration research, 2024-09, Vol.19 (9), p.1875-1876

2024

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NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

Glia, 2015-12, Vol.63 (12), p.2260-2273

2015

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The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins

Cell death and differentiation, 2017-10, Vol.24 (10), p.1655-1671

2017

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Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

Nature biotechnology, 2010-03, Vol.28 (3), p.256-263

2010

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Inhibition of Proteasomal Function by Curcumin Induces Apoptosis through Mitochondrial Pathway

The Journal of biological chemistry, 2004-03, Vol.279 (12), p.11680-11685

2004

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Co-chaperone CHIP Associates with Expanded Polyglutamine Protein and Promotes Their Degradation by Proteasomes

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11635-11640

2005

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The Ubiquitin Ligase E6-AP Is Induced and Recruited to Aggresomes in Response to Proteasome Inhibition and May Be Involved in the Ubiquitination of Hsp70-bound Misfolded Proteins

The Journal of biological chemistry, 2009-04, Vol.284 (16), p.10537-10545

2009

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Aspirin Induces Apoptosis through the Inhibition of Proteasome Function

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.29228-29235

2006

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Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

The Journal of biological chemistry, 2009-05, Vol.284 (19), p.13153-13164

2009

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Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP)

Cells (Basel, Switzerland), 2023-04, Vol.12 (7), p.1094

2023

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Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation

Cell death & disease, 2021-05, Vol.12 (5), p.466-466, Article 466

2021

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Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism

Human molecular genetics, 2008-10, Vol.17 (20), p.3223-3235

2008

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Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)

Brain, behavior, & immunity. Health, 2023-11, Vol.33, p.100686, Article 100686

2023

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Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis

Annals of clinical and translational neurology, 2019-12, Vol.6 (12), p.2384-2394

2019

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Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia

Cell death discovery, 2023-07, Vol.9 (1), p.248-248, Article 248

2023

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Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction

Biochemical and biophysical research communications, 2006-03, Vol.342 (1), p.184-190

2006

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ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT

Molecular neurodegeneration, 2012-08, Vol.7 (1), p.43-43, Article 43

2012

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Cetuximab Induces Eme1-Mediated DNA Repair: a Novel Mechanism for Cetuximab Resistance

Neoplasia (New York, N.Y.), 2014-03, Vol.16 (3), p.207-220.e4

2014

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NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

Glia, 2015-12, Vol.63 (12), p.2260-2273

2015

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Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS

Brain (London, England : 1878), 2023-10, Vol.146 (10), p.4088-4104

2023

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Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction

Biochemical and biophysical research communications, 2006-04, Vol.342 (4), p.1323-1328

2006

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Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction

Journal of neurochemistry, 2009-02, Vol.108 (3), p.787-795

2009

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The Mono-ADP-Ribosyltransferase ARTD10 Regulates KV1.1 through PKCD

Biophysical journal, 2018-02, Vol.114 (3), p.295a-295a

2018

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PML nuclear bodies: new players in familial amyotrophic lateral sclerosis-frontotemporal dementia?

NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation

The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins

FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy

Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein

Inhibition of Proteasomal Function by Curcumin Induces Apoptosis through Mitochondrial Pathway

Co-chaperone CHIP Associates with Expanded Polyglutamine Protein and Promotes Their Degradation by Proteasomes

The Ubiquitin Ligase E6-AP Is Induced and Recruited to Aggresomes in Response to Proteasome Inhibition and May Be Involved in the Ubiquitination of Hsp70-bound Misfolded Proteins

Aspirin Induces Apoptosis through the Inhibition of Proteasome Function

Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP)

Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation

Blocking acid-sensing ion channel 1 alleviates Huntington's disease pathology via an ubiquitin-proteasome system-dependent mechanism

Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)

Phenotypes and malignancy risk of different FUS mutations in genetic amyotrophic lateral sclerosis

Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction

ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT

Cetuximab Induces Eme1-Mediated DNA Repair: a Novel Mechanism for Cetuximab Resistance

NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS

Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction

Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction

The Mono-ADP-Ribosyltransferase ARTD10 Regulates KV1.1 through PKCD

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