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Lytic cell death in metabolic liver disease

Journal of hepatology, 2020-08, Vol.73 (2), p.394-408

2020

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A positive feedback loop between RIP3 and JNK controls non‐alcoholic steatohepatitis

EMBO molecular medicine, 2014-08, Vol.6 (8), p.1062-1074

2014

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Histidine‐rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

Hepatology (Baltimore, Md.), 2016-04, Vol.63 (4), p.1310-1324

2016

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Mediators of necroptosis: from cell death to metabolic regulation

EMBO molecular medicine, 2024-01, Vol.16 (2), p.219-237

2024

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RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8- and JNK-Dependent Compensatory Cell Proliferation

Cell reports (Cambridge), 2013-08, Vol.4 (4), p.776-790

2013

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Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

BMC medicine, 2022-03, Vol.20 (1), p.95-95, Article 95

2022

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Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis

Disease models & mechanisms, 2020-04, Vol.13 (4)

2020

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The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease

International journal of molecular sciences, 2020-12, Vol.22 (1), p.13

2020

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O-GlcNAc transferase acts as a critical nutritional node for the control of liver homeostasis

JHEP reports, 2024-02, Vol.6 (2), p.100878-100878, Article 100878

2024

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MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression

Cells (Basel, Switzerland), 2022-02, Vol.11 (4), p.617

2022

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The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes

iScience, 2022-10, Vol.25 (10), p.105166-105166, Article 105166

2022

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The scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis

Journal of molecular medicine (Berlin, Germany), 2022-07, Vol.100 (7), p.1039-1042

2022

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In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal

Journal of clinical medicine, 2020-12, Vol.10 (1), p.36

2020

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Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease

Journal of hepatology, 2020-04, Vol.72 (4), p.627-635

2020

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NF-κB-Related Genetic Diseases

1st ed. 2016, 2016

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Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5931

2020

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Multiple functions of MLKL in liver fibrosis, from necroptosis to hepatic stellate cell activation

Theranostics, 2022-01, Vol.12 (13), p.5820-5823

2022

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miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib

Journal of hepatology, 2017-11, Vol.67 (5), p.966-978

2017

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RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

Cardiovascular research, 2014-07, Vol.103 (2), p.206-216

2014

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RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer

Cancer cell, 2017-01, Vol.31 (1), p.94-109

2017

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Receptor interacting protein kinase 1 (RIPK1) in hepatocytes does not mediate murine acetaminophen toxicity

Hepatology (Baltimore, Md.), 2016-07, Vol.64 (1), p.306-308

2016

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IKK-related genetic diseases: probing NF-κB functions in humans and other matters

Cellular and molecular life sciences : CMLS, 2015-04, Vol.72 (7), p.1275-1287

2015

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Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1236

2023

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Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis

Hepatology (Baltimore, Md.), 2022-11, Vol.76 (5), p.1360-1375

2022

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The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

Nature communications, 2016-06, Vol.7 (1), p.11869-16, Article 11869

2016

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Lytic cell death in metabolic liver disease

A positive feedback loop between RIP3 and JNK controls non‐alcoholic steatohepatitis

Histidine‐rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

Mediators of necroptosis: from cell death to metabolic regulation

RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8- and JNK-Dependent Compensatory Cell Proliferation

Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis

The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease

O-GlcNAc transferase acts as a critical nutritional node for the control of liver homeostasis

MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression

The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes

The scaffold-dependent function of RIPK1 in experimental non-alcoholic steatohepatitis

In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal

Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease

NF-κB-Related Genetic Diseases

Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury

Multiple functions of MLKL in liver fibrosis, from necroptosis to hepatic stellate cell activation

miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction

RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer

Receptor interacting protein kinase 1 (RIPK1) in hepatocytes does not mediate murine acetaminophen toxicity

IKK-related genetic diseases: probing NF-κB functions in humans and other matters

Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases

Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

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